SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q486J6

- GCSP1_COLP3

UniProt

Q486J6 - GCSP1_COLP3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glycine dehydrogenase (decarboxylating) 1
Gene
gcvP1, CPS_1276
Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine decarboxylation via glycine cleavage system Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciCPSY167879:GI48-1276-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine dehydrogenase (decarboxylating) 1 (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein 1
Glycine decarboxylase 1
Glycine dehydrogenase (aminomethyl-transferring) 1
Gene namesi
Name:gcvP1
Ordered Locus Names:CPS_1276
OrganismiColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Taxonomic identifieri167879 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia
ProteomesiUP000000547: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 965965Glycine dehydrogenase (decarboxylating) 1UniRule annotation
PRO_0000227102Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei713 – 7131N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Protein-protein interaction databases

STRINGi167879.CPS_1276.

Structurei

3D structure databases

ProteinModelPortaliQ486J6.

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family.

Phylogenomic databases

eggNOGiCOG1003.
HOGENOMiHOG000239369.
KOiK00281.
OMAiDSHRNIC.
OrthoDBiEOG6HMXDX.

Family and domain databases

Gene3Di3.40.640.10. 2 hits.
HAMAPiMF_00711. GcvP.
InterProiIPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 2 hits.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 3 hits.
TIGRFAMsiTIGR00461. gcvP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q486J6-1 [UniParc]FASTAAdd to Basket

« Hide

MTSKTIVNSL AELEQTQDFI RRHIGPSESE TQAMLNDLGV ESVDALIDEI    50
VPSDIRLADL PNVEESKTEV QALADLKAVA SLNKVNDTYI GLGYFGTLTP 100
NVILRNVLEN PGWYTAYTPY QPEIAQGRLE SLLNYQQMCI DLTGLELASA 150
SLLDEGTAAA EAMALAKRVS KNKKSNLFFI SDDVYPQTID VVKQRAEMFG 200
FDIVVAPAAD AAEHDIFGAL IQYPGASGQV TDVSELIAKI HDNKGIVAVA 250
ADIMSLVLLK SPGELGADAV IGSSQRFGVP MGYGGPHAAF FTTLDKYKRS 300
LPGRIIGVSK DTRGKNALRM AMQTREQHIR REKANSNVCT AQVLLANMAA 350
FYAVYHGPQG LKTIANRIHR LADILCLGTA TKGLTAVHAN YFDTLTFNVD 400
NKDEIVARAL AANANFRTDV DGQISIALDE TTTRENVAQL FDILLGEGHG 450
LNVSDLDDQI VASGHSSIPA SLVRESAILT HPVFNSYHSE TEMLRYIKRL 500
ENKDLALNHS MISLGSCTMK LNATAQMIPV SWPEFANMHP FAPVNQAQGY 550
KAMIDELAKW LVELTGYDKM SMQPNSGAQG EYAGLIAISK YHESRGDSHR 600
NICLIPASAH GTNPASAMMV DMKIVIVACD KEGNVDMADL KAKAEELADN 650
LACIMITYPS THGVYETTIA EICNIIHDNG GQVYLDGANM NAQVGLTSPG 700
FIGADVSHLN LHKTFAIPHG GGGPGMGPIG VKSHLAPFLP DHALINVDEA 750
TKGNGAVSSA PFGSASILPI TYLYIALLGK KGVTDATKYA ITNANYVSKK 800
LSEHYPILYS GKNGRVAHEC IVDLRPLKAS SGVTEVDMAK RLMDYGFHSP 850
TMSFPVAGTF MIEPTESESK VELDRFIEAM VCIRDEVRKV ESGEWASDNN 900
PLHNAPHTLA DITEPWDRPY SIQEAVFPVV AVTANKFWPT VNRIDDVFGD 950
RNLICSCPPI ESYID 965
Length:965
Mass (Da):104,676
Last modified:September 13, 2005 - v1
Checksum:i2D76B8A433A614DB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000083 Genomic DNA. Translation: AAZ27305.1.
RefSeqiYP_268019.1. NC_003910.7.

Genome annotation databases

EnsemblBacteriaiAAZ27305; AAZ27305; CPS_1276.
GeneIDi3521561.
KEGGicps:CPS_1276.
PATRICi21465787. VBIColPsy94388_1145.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000083 Genomic DNA. Translation: AAZ27305.1 .
RefSeqi YP_268019.1. NC_003910.7.

3D structure databases

ProteinModelPortali Q486J6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167879.CPS_1276.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ27305 ; AAZ27305 ; CPS_1276 .
GeneIDi 3521561.
KEGGi cps:CPS_1276.
PATRICi 21465787. VBIColPsy94388_1145.

Phylogenomic databases

eggNOGi COG1003.
HOGENOMi HOG000239369.
KOi K00281.
OMAi DSHRNIC.
OrthoDBi EOG6HMXDX.

Enzyme and pathway databases

BioCyci CPSY167879:GI48-1276-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 2 hits.
HAMAPi MF_00711. GcvP.
InterProi IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 2 hits.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 3 hits.
TIGRFAMsi TIGR00461. gcvP. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 34H / ATCC BAA-681.

Entry informationi

Entry nameiGCSP1_COLP3
AccessioniPrimary (citable) accession number: Q486J6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi