Q486D8 (Q486D8_COLP3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Choline dehydrogenase EMBL AAZ27841.1
EC=1.1.99.1 EMBL AAZ27841.1

Gene names

Name:	betA1 EMBL AAZ27841.1
Ordered Locus Names:	CPS_1334

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP] EMBL AAZ27841.1

Taxonomic identifier

167879 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length	560 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. SAAS SAAS007867
Cofactor	FAD By similarity. SAAS SAAS007867
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. SAAS SAAS007867

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533
Molecular function	Oxidoreductase SAAS SAAS007867 EMBL AAZ27841.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q486D8 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 1142017F844F5828	FASTA	560	62,411
	10 20 30 40 50 60 MKSEKFDYII VGAGSAGCVL ANRLSEDSNN RVLLLETGGS DKSIFIQMPT ALSIPMNTKK 70 80 90 100 110 120 YAWQFETQPE PFLDERRMHC PRGKVLGGSS SINGMVYVRG HARDFDEWQQ SGAQNWDYAH 130 140 150 160 170 180 CLPYFKKAET WAFDGNEYRG KSGPLGVNNG NEMKNPLYQA FVDAGVEAGY FATDDYNAAA 190 200 210 220 230 240 QEGFGPMHMT VKNGVRCSTA NAYLRPAMAR SNLTVITHAL VHKVLLDGKK TVGVRYERKG 250 260 270 280 290 300 QVFDVSVEKE VILSAGPVGS PHLLQLSGIG AKKDLEDAGI EVQHDLPGVG QNLQDHLEFY 310 320 330 340 350 360 FQFKCKKPIS LNGQLGLWNK FLIGSRWFFT KKGLGATNHF ESCGFIRSKA NVEWPDLQYH 370 380 390 400 410 420 FLPAAMRYDG KEAFAGHGFQ VHIGHNKPKS RGSIKAISND PKAHPQIRFN YLEHEEDREG 430 440 450 460 470 480 FRACVRLTRE IINQSALDEY RGEEIQPGIN VQSDEEIDAF VRQFVESAYH PSCSCKMGTD 490 500 510 520 530 540 ELAVVDSETR VHGIEGLRVV DSSIFPTIPN GNLNAPTIMV AERAADLIRG REILAPSQAA 550 560 VKIAPNWQQQ QRANEPKRKI

References

[1]

"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000083 Genomic DNA. Translation: AAZ27841.1.
RefSeq	YP_268077.1. NC_003910.7.
3D structure databases
ProteinModelPortal	Q486D8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q486D8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3522100.
GenomeReviews	Gene locus CPS_1334 in contig CP000083_GR.
KEGG	cps:CPS_1334.
NMPDR	fig|167879.3.peg.1295.
PATRIC	21465891. VBIColPsy94388_1197.
TIGR	CPS_1334.
Phylogenomic databases
eggNOG	COG2303.
HOGENOM	HBG734713.
OMA	HMTVKNG.
ProtClustDB	PRK02106.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q486D8_COLP3

Accession

Primary (citable) accession number: Q486D8

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)