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Protein

Alkaline phosphatase-like protein

Gene

apl

Organism
Lactococcus lactis subsp. cremoris (strain MG1363)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciLLAC416870:GCDT-1860-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline phosphatase-like protein
Gene namesi
Name:apl
Ordered Locus Names:llmg_1854
OrganismiLactococcus lactis subsp. cremoris (strain MG1363)
Taxonomic identifieri416870 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
ProteomesiUP000000364 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321HelicalSequence AnalysisAdd
BLAST
Transmembranei48 – 6821HelicalSequence AnalysisAdd
BLAST
Transmembranei141 – 16121HelicalSequence AnalysisAdd
BLAST
Transmembranei177 – 19721HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 214214Alkaline phosphatase-like proteinPRO_0000161409Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi416870.llmg_1854.

Structurei

3D structure databases

ProteinModelPortaliQ48630.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DedA family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0586.
HOGENOMiHOG000105369.
KOiK01077.
OMAiKMKMSRF.
OrthoDBiEOG68DD4N.

Sequencei

Sequence statusi: Complete.

Q48630-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQEIIIQVMN QFGYFGVAFL IMIENIFPPI PSEVILTFGG FMTTYSELGI
60 70 80 90 100
IGMIIAATIG SVLGALILYF VGRLLSVERL ERLVSGRLGK VLRLKPEDIT
110 120 130 140 150
KAEKWFLKRG YATIFFCRFI PLIRSLISVP AGSAKMKLPS FLILTTLGTL
160 170 180 190 200
IWNIVLVSLG AALGDNWEMI AGILDSYSSV VVAILGVIFI LGLLLFVKKR
210
FFPKNKNYSP DSEK
Length:214
Mass (Da):23,760
Last modified:May 1, 2007 - v2
Checksum:i8CC155CF4211CEDC
GO

Sequence cautioni

The sequence CAA82306.1 differs from that shown. Reason: Frameshift at position 205. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z29065 Genomic DNA. Translation: CAA82306.1. Frameshift.
AM406671 Genomic DNA. Translation: CAL98425.1.
PIRiS39339.
RefSeqiWP_011835619.1. NC_009004.1.

Genome annotation databases

EnsemblBacteriaiCAL98425; CAL98425; llmg_1854.
KEGGillm:llmg_1854.
PATRICi22284889. VBILacLac4574_1898.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z29065 Genomic DNA. Translation: CAA82306.1. Frameshift.
AM406671 Genomic DNA. Translation: CAL98425.1.
PIRiS39339.
RefSeqiWP_011835619.1. NC_009004.1.

3D structure databases

ProteinModelPortaliQ48630.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi416870.llmg_1854.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL98425; CAL98425; llmg_1854.
KEGGillm:llmg_1854.
PATRICi22284889. VBILacLac4574_1898.

Phylogenomic databases

eggNOGiCOG0586.
HOGENOMiHOG000105369.
KOiK01077.
OMAiKMKMSRF.
OrthoDBiEOG68DD4N.

Enzyme and pathway databases

BioCyciLLAC416870:GCDT-1860-MONOMER.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and sequencing of a gene (apl) from Lactococcus lactis that can complement a phoA mutation in Escherichia coli."
    Venema K., Haandrikman A., Leenhouts K., Kok J., Venema G.
    Submitted (DEC-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363."
    Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.
    J. Bacteriol. 189:3256-3270(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MG1363.

Entry informationi

Entry nameiAPL_LACLM
AccessioniPrimary (citable) accession number: Q48630
Secondary accession number(s): A2RM98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 1, 2007
Last modified: July 22, 2015
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.