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Q48630 (APL_LACLM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alkaline phosphatase-like protein
Gene names
Name:apl
Ordered Locus Names:llmg_1854
OrganismLactococcus lactis subsp. cremoris (strain MG1363) [Complete proteome] [HAMAP]
Taxonomic identifier416870 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus

Protein attributes

Sequence length214 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the DedA family.

Sequence caution

The sequence CAA82306.1 differs from that shown. Reason: Frameshift at position 205.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 214214Alkaline phosphatase-like protein
PRO_0000161409

Regions

Transmembrane3 – 2321Helical; Potential
Transmembrane48 – 6821Helical; Potential
Transmembrane141 – 16121Helical; Potential
Transmembrane177 – 19721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q48630 [UniParc].

Last modified May 1, 2007. Version 2.
Checksum: 8CC155CF4211CEDC

FASTA21423,760
        10         20         30         40         50         60 
MQEIIIQVMN QFGYFGVAFL IMIENIFPPI PSEVILTFGG FMTTYSELGI IGMIIAATIG 

        70         80         90        100        110        120 
SVLGALILYF VGRLLSVERL ERLVSGRLGK VLRLKPEDIT KAEKWFLKRG YATIFFCRFI 

       130        140        150        160        170        180 
PLIRSLISVP AGSAKMKLPS FLILTTLGTL IWNIVLVSLG AALGDNWEMI AGILDSYSSV 

       190        200        210 
VVAILGVIFI LGLLLFVKKR FFPKNKNYSP DSEK 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and sequencing of a gene (apl) from Lactococcus lactis that can complement a phoA mutation in Escherichia coli."
Venema K., Haandrikman A., Leenhouts K., Kok J., Venema G.
Submitted (DEC-1993) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363."
Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.
J. Bacteriol. 189:3256-3270(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MG1363.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z29065 Genomic DNA. Translation: CAA82306.1. Frameshift.
AM406671 Genomic DNA. Translation: CAL98425.1.
PIRS39339.
RefSeqYP_001033126.1. NC_009004.1.

3D structure databases

ProteinModelPortalQ48630.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING416870.llmg_1854.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL98425; CAL98425; llmg_1854.
GeneID4797386.
KEGGllm:llmg_1854.
PATRIC22284889. VBILacLac4574_1898.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0586.
HOGENOMHOG000105369.
KOK01077.
OMAESWNEIV.
OrthoDBEOG68DD4N.

Enzyme and pathway databases

BioCycLLAC416870:GCDT-1860-MONOMER.

Family and domain databases

InterProIPR015414. SNARE_assoc.
[Graphical view]
PfamPF09335. SNARE_assoc. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAPL_LACLM
AccessionPrimary (citable) accession number: Q48630
Secondary accession number(s): A2RM98
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 1, 2007
Last modified: May 14, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families