Q485H4 (GLND_COLP3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	CPS_1549

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]

Taxonomic identifier

167879 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length	878 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 878	878	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_0000192729

Sequences

	Sequence		Length	Mass (Da)
	Q485H4 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 90026DD7C373EF21	FASTA	878	101,844
	10 20 30 40 50 60 MTSHPVSVHI VPSHFINQLA ISADFLSTRD ICQLSQSFNT WLKDVFIEND INDLLSARAV 70 80 90 100 110 120 FVDAILKKLW CQHHLDEFQI TLIAVGGYGR GELHPQSDVD ILLLTQEEVD LELEEKISSF 130 140 150 160 170 180 ITQLWDIKLD IGHSVRSIKE CLKQAVKEVT VATNLMEMRQ VAGNETLTQQ LTPLLSEDVF 190 200 210 220 230 240 WTSEKFFIAK CKEQEARHQQ YRGAAYTLEP NLKANPGGLR DIQTIAWVAK RHFSADSLEE 250 260 270 280 290 300 LVEHDYLYPN EFFELLESQD YLWRMRFALH FVAGRSENRL LFDYQADVAK MMGFGDEGKA 310 320 330 340 350 360 PVERMMKRFF RIIARVTELN TMLLQHFEQA IIKKPELSNI SIINQDFELV DKLINTRNDR 370 380 390 400 410 420 IFMRPVKMIE MFLIIAQEPG IKGIHSHTMR LMRNARRRLI SGLIDYAECR RMFMAIIRHP 430 440 450 460 470 480 RGLGLALTLM HRHSILSSYL PLWRNIAGQM QFDLFHAYSV DEHSYRVIKN LHQFSQKEHN 490 500 510 520 530 540 HKFPLCSKIV QKIRKPEVLY LAGFFHDIGK GRGGDHAKLG AVDALTFCLS HQLSKHDSNM 550 560 570 580 590 600 VAWLVEHHLL MSVTAQRRDI NDENVIRTFG EIVRDEAHLN YLYCLTVADM RGTNESLWNN 610 620 630 640 650 660 WKANLLEELY FNTLSAFRHG LEKPVEVRSK IRENQQQALA LLNENNVDEQ SIKALWREFR 670 680 690 700 710 720 IDYFLRYSPE QIARQCQNIV EHDREKPLVL ISPIPYRGGT EVFIFTKEKN NTFASTVSFL 730 740 750 760 770 780 VTKKLSIHDA KIITTKTGYT VNTFVVLDSR NKPLRERFYT KEMSQALVDR LQQVNICELP 790 800 810 820 830 840 EPKLARHMKK FKVPLRVNFI KIHAKNRTMI EIIALDRPGL LSNISQVFLE ARVNIHSAKI 850 860 870 TTFGEKADDV FTISTEEDDA LTTQEKEALA LRLTQEID

References

[1]

"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 34H / ATCC BAA-681.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000083 Genomic DNA. Translation: AAZ26298.1.
RefSeq	YP_268291.1. NC_003910.7.
3D structure databases
ProteinModelPortal	Q485H4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q485H4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3520548.
GenomeReviews	Gene locus CPS_1549 in contig CP000083_GR.
KEGG	cps:CPS_1549.
NMPDR	fig|167879.3.peg.1810.
PATRIC	21466307. VBIColPsy94388_1405.
TIGR	CPS_1549.
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HBG687872.
OMA	MQHDLFH.
Enzyme and pathway databases
BioCyc	CPSY167879:CPS_1549-MONOMER.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl-transf. [Tree]
InterPro	IPR002912. ACT-bd. IPR010043. GlnD_Uridyltrans. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_COLP3

Accession

Primary (citable) accession number: Q485H4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2005
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program