Q48451 (YOR5_KLEPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Putative low molecular weight protein-tyrosine-phosphatase EC=3.1.3.48 Alternative name(s): ORF5
Organism	Klebsiella pneumoniae
Taxonomic identifier	573 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length	144 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Sequence similarities	Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Keywords
Molecular function	Hydrolase Protein phosphatase
Gene Ontology (GO)
Biological_process	peptidyl-tyrosine dephosphorylation Inferred from electronic annotation. Source: GOC
Molecular_function	protein tyrosine phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 144	144	Putative low molecular weight protein-tyrosine-phosphatase		PRO_0000046580
Sites
	Active site	9	1	Nucleophile By similarity
	Active site	14	1	By similarity
	Active site	115	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q48451 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 6F1F43503371DFF1	FASTA	144	16,141
	10 20 30 40 50 60 MFSTILIVCT GNICRSPIGE RYLQQLLPSK NISSAGTQAL VDHEADQSAV EVARKNGISL 70 80 90 100 110 120 AGHLGRQFTS KLSKEYELIL VMEKNHIEQI SNIAPEARGK TMLFGHWLEQ RDIPDPYRKS 130 140 EEAFASVFKL IEQSALLWAE KLKA

References

[1]

"Genomic organization of the Klebsiella pneumoniae cps region responsible for serotype K2 capsular polysaccharide synthesis in the virulent strain Chedid." Arakawa Y., Wacharotayankun R., Nagatsuka T., Ito H., Kato N., Ohta M. J. Bacteriol. 177:1788-1796(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Chedid.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D21242 Genomic DNA. Translation: BAA04776.1.
3D structure databases
ProteinModelPortal	Q48451.
SMR	Q48451. Positions 1-144.
ModBase	Search...
Protein family/group databases
PptaseDB	P3D0409134.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR023485. Ptyr_pPase_SF. IPR000106. Tyr_phospatase/Ars_reductase. IPR017867. Tyr_phospatase_low_mol_wt. [Graphical view]
PANTHER	PTHR11717. PTHR11717. 1 hit.
Pfam	PF01451. LMWPc. 1 hit. [Graphical view]
PRINTS	PR00719. LMWPTPASE.
SMART	SM00226. LMWPc. 1 hit. [Graphical view]
SUPFAM	SSF52788. Tyr_Pase_low_mol_wt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

YOR5_KLEPN

Accession

Primary (citable) accession number: Q48451

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	April 3, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program