Reviewed, UniProtKB/Swiss-Prot Q48409 (CASB_KLEOX)

Names and origin

Protein names

Recommended name:
    Phospho-cellobiase
    EC=3.2.1.-

Gene names

Name:

casB

Organism

Klebsiella oxytoca

Taxonomic identifier

571 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length	464 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 1 family.

Ontologies

Keywords
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 464	464	Phospho-cellobiase		PRO_0000063900
Sites
	Active site	172	1	Proton donor Potential
	Active site	361	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q48409-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 92F744FE5ADF6C38	FASTA	464	52,242
	10 20 30 40 50 60 MKTFPQAFLW GGATAANQVE GAYLEDGKGL TTSDVQPRGV FGDVVERVPG DSGIKDIAID 70 80 90 100 110 120 FYHRYPEDIS LFAEMGFNCL RVSIAWARIF PHGDEAQPNE AGLAFYDKLF DEMAKHNITP 130 140 150 160 170 180 LVTLSHYEMP WALVKNYGGW GNRKVIGFFE RYARTVFERY QAKVKLWLTF NEINMSLHAP 190 200 210 220 230 240 MTGVGLPADS SKAEVYQAIH HQLVASALAA KACHDIVPEG KIGNMLLGGL MYPLSCKPDD 250 260 270 280 290 300 IFETLQQNRS WQFFGDVQCR GAYPGYMLRY FRDNGINLDI TDADRAALKE TVDFISFSYY 310 320 330 340 350 360 MTGCVTADEE LNKKARGNIL SMVPNPHLAS SEWGWQIDPL GLRTLLNVLW DRYQKPLFIV 370 380 390 400 410 420 ENGLGAKDKV EADGSINDDY RISYLNDHLV QVREAIEDGV ELMGYTSWGP IDLVSASKAE 430 440 450 460 MSKRYGFIYV DRDDDGNGTL ARSRKKSFWW YKEVIATNGG SLKE

References

[1]

"Cloning of cellobiose phosphoenolpyruvate-dependent phosphotransferase genes: functional expression in recombinant Escherichia coli and identification of a putative binding region for disaccharides." Lai X., Davis F.C., Hespell R.B., Ingram L.O. Appl. Environ. Microbiol. 63:355-363(1997) [PubMed: 9023916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: P2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U61727 Genomic DNA. Translation: AAB51564.1.
3D structure databases
HSSP	HSSP built from PDB template 1PBG based on UniProtKB P11546.
ModBase	Search...
Family and domain databases
InterPro	IPR001360. Glyco_hydro_1. IPR013781. Glyco_hydro_sub_cat. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
PANTHER	PTHR10353. Glyco_hydro_1. 1 hit.
Pfam	PF00232. Glyco_hydro_1. 1 hit. [Graphical view]
PRINTS	PR00131. GLHYDRLASE1.
PROSITE	PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit. PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CASB_KLEOX

Accession

Primary (citable) accession number: Q48409

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	November 25, 2008
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)