Reviewed, UniProtKB/Swiss-Prot Q483D3 (G6PI2_COLP3)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase 2
      Short name=GPI 2
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase 2
      Short name=PGI 2
    Phosphohexose isomerase 2
      Short name=PHI 2

Gene names

Name:	pgi2
Ordered Locus Names:	CPS_2108

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]

Taxonomic identifier

167879 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length	551 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 551	551	Glucose-6-phosphate isomerase 2 HAMAP MF_00473		PRO_0000180630
Sites
	Active site	353	1	Proton donor By similarity
	Active site	384	1	By similarity
	Active site	512	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q483D3-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 79AC8B0F995DD572	FASTA	551	60,730
	10 20 30 40 50 60 MDIKKLSSLA HCAKTRSIVS LFDQKERAND FSLSTSHLYL DYSKQNITDV ELEQLIEIAE 70 80 90 100 110 120 DVGLSESITG QFNGDKINNT EGRSVLHTIL RAPQVIKQQI LGDTLANEVE AAELQMAKVV 130 140 150 160 170 180 NDVQKGILTS HTGQRFTDVL AIGIGGSYYG VKVSLSALEH YRDLALSVHV IANVDGGALE 190 200 210 220 230 240 EKLKTLNFET TLVVVISKTF TTQETMLNAK AVKQWMLSCA SVKDLELNNV PLIIEKQWFA 250 260 270 280 290 300 VSSNIEAAKE FGINIKHILP MWDWVGGRFS IWSTVGLPLA LAIGNDNFNK LKQGAYEMDV 310 320 330 340 350 360 HFKSTDFKNN MPVIMALLGI WNRNALEYPT LAILPYAHSL RALPGYLQQT DMESNGKSVS 370 380 390 400 410 420 KSGDKLSWLT APVVFGQEGT NGQHAFMQLM HQSDDIIPTD FIVALKGRSQ YTENHKVLVA 430 440 450 460 470 480 NCFAQSEALM QGKTLTQVES ELEMSALSTA EISLIAPHKT MKGNTPSNTL VMDLLTPETI 490 500 510 520 530 540 GSLLALYEHK IFVQGVLWQV NSFDQWGVEL GKQLGTRILS AIDGAEDDLL SASSQSLIAR 550 FRARSNVTPS V

References

[1]

"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000083 Genomic DNA. Translation: AAZ25825.1.
RefSeq	YP_268834.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3520071.
GenomeReviews	Gene locus CPS_2108 in contig CP000083_GR.
KEGG	cps:CPS_2108.
NMPDR	fig|167879.3.peg.2020.
TIGR	CPS_2108.
Phylogenomic databases
HOGENOM	Q483D3.
OMA	Q483D3. NSPDINF.
Enzyme and pathway databases
BioCyc	CPSY167879:CPS_2108-MON.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI2_COLP3

Accession

Primary (citable) accession number: Q483D3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2005
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)