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Q483D3 (G6PI2_COLP3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase 2

Short name=GPI 2
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 2
Short name=PGI 2
Phosphohexose isomerase 2
Short name=PHI 2
Gene names
Name:pgi2
Ordered Locus Names:CPS_2108
OrganismColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]
Taxonomic identifier167879 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 551551Glucose-6-phosphate isomerase 2 HAMAP-Rule MF_00473
PRO_0000180630

Sites

Active site3531Proton donor By similarity
Active site3841 By similarity
Active site5121 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q483D3 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 79AC8B0F995DD572

FASTA55160,730
        10         20         30         40         50         60 
MDIKKLSSLA HCAKTRSIVS LFDQKERAND FSLSTSHLYL DYSKQNITDV ELEQLIEIAE 

        70         80         90        100        110        120 
DVGLSESITG QFNGDKINNT EGRSVLHTIL RAPQVIKQQI LGDTLANEVE AAELQMAKVV 

       130        140        150        160        170        180 
NDVQKGILTS HTGQRFTDVL AIGIGGSYYG VKVSLSALEH YRDLALSVHV IANVDGGALE 

       190        200        210        220        230        240 
EKLKTLNFET TLVVVISKTF TTQETMLNAK AVKQWMLSCA SVKDLELNNV PLIIEKQWFA 

       250        260        270        280        290        300 
VSSNIEAAKE FGINIKHILP MWDWVGGRFS IWSTVGLPLA LAIGNDNFNK LKQGAYEMDV 

       310        320        330        340        350        360 
HFKSTDFKNN MPVIMALLGI WNRNALEYPT LAILPYAHSL RALPGYLQQT DMESNGKSVS 

       370        380        390        400        410        420 
KSGDKLSWLT APVVFGQEGT NGQHAFMQLM HQSDDIIPTD FIVALKGRSQ YTENHKVLVA 

       430        440        450        460        470        480 
NCFAQSEALM QGKTLTQVES ELEMSALSTA EISLIAPHKT MKGNTPSNTL VMDLLTPETI 

       490        500        510        520        530        540 
GSLLALYEHK IFVQGVLWQV NSFDQWGVEL GKQLGTRILS AIDGAEDDLL SASSQSLIAR 

       550 
FRARSNVTPS V 

« Hide

References

[1]"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses."
Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. expand/collapse author list , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 34H / ATCC BAA-681.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000083 Genomic DNA. Translation: AAZ25825.1.
RefSeqYP_268834.1. NC_003910.7.

3D structure databases

ProteinModelPortalQ483D3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING167879.CPS_2108.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ25825; AAZ25825; CPS_2108.
GeneID3520071.
KEGGcps:CPS_2108.
PATRIC21467329. VBIColPsy94388_1905.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMAQKERAND.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycCPSY167879:GI48-2108-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI2_COLP3
AccessionPrimary (citable) accession number: Q483D3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: September 13, 2005
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways