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Protein

TATA-box-binding protein B

Gene

tbpB1

more
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-box-binding protein B
Alternative name(s):
Box A-binding protein B
Short name:
BAP B
TATA sequence-binding protein B
Short name:
TBP B
TATA-box factor B
Gene namesi
Name:tbpB1
Ordered Locus Names:VNG_5052G
AND
Name:tbpB2
Ordered Locus Names:VNG_5245G
AND
Name:tbpB3
Ordered Locus Names:VNG_6050G
AND
Name:tbpB4
Ordered Locus Names:VNG_6476G
Encoded oniPlasmid pNRC1001 Publication
Plasmid pNRC2001 Publication
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componentsi: Plasmid pNRC100, Plasmid pNRC200

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 186186TATA-box-binding protein BPRO_0000154000Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ48325.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati10 – 86771Add
BLAST
Repeati101 – 179792Add
BLAST

Sequence similaritiesi

Belongs to the TBP family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

InParanoidiQ48325.
KOiK03120.
OMAiLTEYRKC.

Family and domain databases

Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q48325-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLADTIHI ENVVASSDLG QELALDQLST DLPGAEYNPE DFPGVVYRLQ
60 70 80 90 100
EPKSATLIFR SGKVVCTGAK SVDDVHEALG IVFGDIRELG IDVTSNPPIE
110 120 130 140 150
VQNIVSSASL EQSLNLNAIA IGLGLEQIEY EPEQFPGLVY RLDDPDVVVL
160 170 180
LFGSGKLVIT GGQNPDEAEQ ALAHVQDRLT ELGLLD
Length:186
Mass (Da):19,938
Last modified:November 1, 1996 - v1
Checksum:i40F54B2CCAF29C97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X93206 Genomic DNA. Translation: CAA63691.1.
AF016485 Genomic DNA. Translation: AAC82955.1.
AF016485 Genomic DNA. Translation: AAC82822.1.
AE004438 Genomic DNA. Translation: AAG21065.1.
AE004438 Genomic DNA. Translation: AAG20743.1.
PIRiT08255.
T44922.
RefSeqiWP_010890411.1. NC_002608.1.

Genome annotation databases

EnsemblBacteriaiAAC82822; AAC82822; AAC82822.
AAC82955; AAC82955; AAC82955.
AAG20743; AAG20743; VNG_6050G.
AAG21065; AAG21065; VNG_6476G.
GeneIDi1449440.
KEGGihal:VNG6050G.
hal:VNG6476G.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X93206 Genomic DNA. Translation: CAA63691.1.
AF016485 Genomic DNA. Translation: AAC82955.1.
AF016485 Genomic DNA. Translation: AAC82822.1.
AE004438 Genomic DNA. Translation: AAG21065.1.
AE004438 Genomic DNA. Translation: AAG20743.1.
PIRiT08255.
T44922.
RefSeqiWP_010890411.1. NC_002608.1.

3D structure databases

ProteinModelPortaliQ48325.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC82822; AAC82822; AAC82822.
AAC82955; AAC82955; AAC82955.
AAG20743; AAG20743; VNG_6050G.
AAG21065; AAG21065; VNG_6476G.
GeneIDi1449440.
KEGGihal:VNG6050G.
hal:VNG6476G.

Phylogenomic databases

InParanoidiQ48325.
KOiK03120.
OMAiLTEYRKC.

Family and domain databases

Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The TATA-box-binding protein (TBP) of Halobacterium salinarum. Cloning of the tbp gene, heterologous production of TBP and folding of TBP into a native conformation."
    Soppa J., Link T.A.
    Eur. J. Biochem. 249:318-324(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid or minichromosome?"
    Ng W.V., Ciufo S.A., Smith T.M., Bumgarner R.E., Baskin D., Faust J., Hall B., Loretz C., Seto J., Slagel J., Hood L., DasSarma S.
    Genome Res. 8:1131-1141(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700922 / JCM 11081 / NRC-1.
    Plasmid: pNRC100
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700922 / JCM 11081 / NRC-1.
    Plasmid: pNRC200

Entry informationi

Entry nameiTBPB_HALSA
AccessioniPrimary (citable) accession number: Q48325
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: November 1, 1996
Last modified: November 11, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.