ID   RLMF_COLP3              Reviewed;         301 AA.
AC   Q482M9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 19.
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase F;
DE            EC=2.1.1.48;
DE   AltName: Full=23S rRNA mA1618 methyltransferase;
DE   AltName: Full=rRNA adenine N-6-methyltransferase;
GN   Name=rlmF; OrderedLocusNames=CPS_2268;
OS   Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio
OS   psychroerythus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Colwelliaceae; Colwellia.
OX   NCBI_TaxID=167879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16043709; DOI=10.1073/pnas.0504766102;
RA   Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X.,
RA   Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M.,
RA   Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A.,
RA   Zhou L., Davidsen T.M., Wu M., Huston A.L., Lewis M., Weaver B.,
RA   Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.;
RT   "The psychrophilic lifestyle as revealed by the genome sequence of
RT   Colwellia psychrerythraea 34H through genomic and proteomic
RT   analyses.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005).
CC   -!- FUNCTION: Specifically methylates the adenine in position 1618 of
CC       23S rRNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-
CC       homocysteine + rRNA containing N(6)-methyladenine.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       METT10D/rlmF family.
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DR   EMBL; CP000083; AAZ28550.1; -; Genomic_DNA.
DR   RefSeq; YP_268988.1; -.
DR   GeneID; 3522810; -.
DR   GenomeReviews; CP000083_GR; CPS_2268.
DR   KEGG; cps:CPS_2268; -.
DR   NMPDR; fig|167879.3.peg.2205; -.
DR   TIGR; CPS_2268; -.
DR   HOGENOM; Q482M9; -.
DR   OMA; Q482M9; LNFGGQN.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008988; F:rRNA (adenine-N6-)-methyltransferase activity; IEA:HAMAP.
DR   GO; GO:0000154; P:rRNA modification; IEA:InterPro.
DR   HAMAP; MF_01848; -; 1.
DR   InterPro; IPR016909; S-AdoMet-dep_MeTrfase_YbiN_prd.
DR   InterPro; IPR010286; SAM-Mtase_prd.
DR   PANTHER; PTHR13393; DUF890; 1.
DR   Pfam; PF05971; Methyltransf_10; 1.
DR   PIRSF; PIRSF029038; Mtase_YbiN_prd; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    301       Ribosomal RNA large subunit
FT                                methyltransferase F.
FT                                /FTId=PRO_0000349899.
SQ   SEQUENCE   301 AA;  34029 MW;  A6A8292FC3745B7F CRC64;
     MHKKNRHNQG YNFTALVKAH PGLLQFIIKN QYNNQDTIDF ANPQAVKALN LSLLKSEYHV
     KFWDIPDGYL CPAIPGRVDY IHHLQDLLAA TPKTLLPNKT PINVLDIGTG ASCIYPILGQ
     REYDWHFVAS DVDPISIKVA KHIISSDKSL NRNINCRLQP NSNQIFNGII AEDEFYHLTI
     CNPPFHSSLA EASKGTARKI KNLNKGNHSS KNQDKTLNFG GQKAELWCPG GELAFIGKMI
     KESKAYQKQV LWFTCLVSKK DHLSKLKLSL KKSDAKQIKV IDMAQGQKIS RFIAWSFYDV
     N
//