Reviewed, UniProtKB/Swiss-Prot Q480H7 (DCD_COLP3)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CPS_2837

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]

Taxonomic identifier

167879 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 198	198	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009710

Sequences

	Sequence		Length	Mass (Da)
	Q480H7-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 806557C89D6B79BA	FASTA	198	22,089
	10 20 30 40 50 60 MRLCDKDIEQ YLDDEKIIIE PKPDSSMISG VSVDIRLGNE FRVFQDHTAP YIDLSAPKGE 70 80 90 100 110 120 VQEAMNSIMS DEIFIADGDA FFLHPGELAL AVTYESVTLP DNIVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WSGQIVLEFY NSGKLPLALR PKMKIAALNF ETMSSSAARP YNKREDAKYR 190 DQKGAVASRI SQDEKVNK

References

[1]

"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000083 Genomic DNA. Translation: AAZ24162.1.
RefSeq	YP_269542.1.
3D structure databases
SMR	Q480H7. Positions 1-193.
ModBase	Search...
Genome annotation databases
GeneID	3519588.
GenomeReviews	Gene locus CPS_2837 in contig CP000083_GR.
KEGG	cps:CPS_2837.
NMPDR	fig|167879.3.peg.2689.
TIGR	CPS_2837.
Phylogenomic databases
HOGENOM	Q480H7.
OMA	Q480H7. GSRYQGQ.
Enzyme and pathway databases
BioCyc	CPSY167879:CPS_2837-MON.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. DeoxyUTPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_COLP3

Accession

Primary (citable) accession number: Q480H7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)