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Q47Z78

- PUR5_COLP3

UniProt

Q47Z78 - PUR5_COLP3

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Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, CPS_3196
Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPSY167879:GI48-3196-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:CPS_3196
OrganismiColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Taxonomic identifieri167879 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia
ProteomesiUP000000547: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_0000258348Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi167879.CPS_3196.

Structurei

3D structure databases

ProteinModelPortaliQ47Z78.
SMRiQ47Z78. Positions 7-344.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q47Z78-1 [UniParc]FASTAAdd to Basket

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MSEQKQSLSY KDAGVDIDAG NALVENIKGA VKRTTRPEVM GGLGGFGSVC    50
QLPTGYKEPV LVAGTDGVGT KLRLAIDLAK HDTVGIDLVA MCVNDLIVQG 100
AEPLFFLDYY ATAKLDVAVA SSVVEGIAEG CIQSGCALVG GETAEMPGMY 150
HKGDYDIAGF CVGVAEKSRL IDGTNVAAGD QLIALGASGP HSNGFSLIRK 200
VLEVNNTDTN ELLEGKKIAD HLLEPTKIYV KSVLELLKNV DVHALSHITG 250
GGFWENIPRV LPETAQAVIK GDSWQWPSIF NWLQENGNIT EHEMYRTFNC 300
GVGMVIVVPA DKVAQSIEVL TAHGENAWHL GEIADKADGE EQVVFA 346
Length:346
Mass (Da):36,849
Last modified:September 13, 2005 - v1
Checksum:iD2E9B0EFE11AC0DC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000083 Genomic DNA. Translation: AAZ25488.1.
RefSeqiYP_269892.1. NC_003910.7.

Genome annotation databases

EnsemblBacteriaiAAZ25488; AAZ25488; CPS_3196.
GeneIDi3519204.
KEGGicps:CPS_3196.
PATRICi21469377. VBIColPsy94388_2908.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000083 Genomic DNA. Translation: AAZ25488.1 .
RefSeqi YP_269892.1. NC_003910.7.

3D structure databases

ProteinModelPortali Q47Z78.
SMRi Q47Z78. Positions 7-344.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167879.CPS_3196.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ25488 ; AAZ25488 ; CPS_3196 .
GeneIDi 3519204.
KEGGi cps:CPS_3196.
PATRICi 21469377. VBIColPsy94388_2908.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci CPSY167879:GI48-3196-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 34H / ATCC BAA-681.

Entry informationi

Entry nameiPUR5_COLP3
AccessioniPrimary (citable) accession number: Q47Z78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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