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Q47Z40 (SYQ_COLP3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:CPS_3240
OrganismColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]
Taxonomic identifier167879 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_1000095486

Regions

Motif34 – 4411"HIGH" region HAMAP-Rule MF_00126
Motif268 – 2725"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2711ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q47Z40 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: DD3778A8708F20FD

FASTA55663,750
        10         20         30         40         50         60 
MSDTENRPTN FIRNIIDADL DSGKHTGVQT RFPPEPNGFL HIGHAKAICL NFGIAQDYNG 

        70         80         90        100        110        120 
LCNLRFDDTN PEKEDIDYVH AIQKDVKWLG FEWAGEIHYS SNYFDQLHGF AVELIEKGLA 

       130        140        150        160        170        180 
YVCFLNAEET REYRGTLNKP GKNSPYRDTS VEENLALFAK MKNGEFEEGI CALRAKIDMT 

       190        200        210        220        230        240 
SSFMCLRDPI IYRVRFAHHH QTGDKWCIYP MYDFTHCLSD ALEGITHSIC TLEFQDNRRL 

       250        260        270        280        290        300 
YDWVIEQVSV PSTPHQYEFS RLNLEYTLMS KRKLNTLVEE KLVDSWDDPR MPTIAAFRRR 

       310        320        330        340        350        360 
GYTPASMREF AKRIGVTKME NTIEMSVLEA CIREDLNDNA PRAMAVLDPI KLVIENYPED 

       370        380        390        400        410        420 
KNEDLIVKNH PSDDEQGTRI VPFSKELYIE AEDFREEANK KYKRLVIDKA VRLRGAYVVT 

       430        440        450        460        470        480 
ATRCDKDEQG NVTTVYCTYN EDTLGKNPTD GTKPKGVIHW VDANKSLDAI VRLYDRLFTV 

       490        500        510        520        530        540 
PNPAAADDFN SVINPQSLVT ITGAKVEPSL AEAKPEFAYQ FERQGYFCLD NDIKEPGALV 

       550 
FNRTVGLRDT WAKISQ 

« Hide

References

[1]"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses."
Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. expand/collapse author list , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 34H / ATCC BAA-681.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000083 Genomic DNA. Translation: AAZ27222.1.
RefSeqYP_269930.1. NC_003910.7.

3D structure databases

ProteinModelPortalQ47Z40.
SMRQ47Z40. Positions 9-550.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING167879.CPS_3240.

Proteomic databases

PRIDEQ47Z40.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ27222; AAZ27222; CPS_3240.
GeneID3521478.
KEGGcps:CPS_3240.
PATRIC21469457. VBIColPsy94388_2942.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMASREIYID.
OrthoDBEOG6DRPF7.

Enzyme and pathway databases

BioCycCPSY167879:GI48-3240-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_COLP3
AccessionPrimary (citable) accession number: Q47Z40
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries