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Q47X57 (Q47X57_COLP3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acs EMBL AAZ26507.1
Synonyms:acsA HAMAP MF_01123
Ordered Locus Names:CPS_3955
OrganismColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP] EMBL AAZ26507.1
Taxonomic identifier167879 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length648 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5151 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6071N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
Q47X57 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 12B79CF080B776AB

FASTA64871,614
        10         20         30         40         50         60 
MKELKSCYPV SEKAKAHTHI DAATYDAMYK KSIEQPDEFW GEQAKEFIDW YKPWDSVSKV 

        70         80         90        100        110        120 
DLKNSEINWF SGGKLNVSYN CIDRHLATKA NDTAIIFEGD DPNDDSKVTY QELHDHVCRF 

       130        140        150        160        170        180 
ANLLKERGVK KGDRVCIYMP MIPEVGYAML ACARIGAIHS VVFGGFSTES IKARVLDADC 

       190        200        210        220        230        240 
KVVITADQSL RGGKRIPLKS NVDAAVIDCP NVHSVIVVAR TGGDVAWNDK VDINYEEAVA 

       250        260        270        280        290        300 
KQSAICEPEV MDAEDPLFVL YTSGSTGTPK GVVHTCGGYI LYAAMTHKYV FDYKEGEVYW 

       310        320        330        340        350        360 
CTADAGWITG HSYIFYGPLA NGATTLVFEG VPTYPDAGRF WQVCEKHKVN VFYTAPTAIR 

       370        380        390        400        410        420 
ALMSIGDDLV NQADLSSLRL LGTVGEPINP EAWHWYYEVV GKSNCPIVDT WWQTETGGIL 

       430        440        450        460        470        480 
ITSLPGAVDM KPGCAGKPFF GVQPALFDKD GNTLEGENAG LLVMTASWPG QLRTVYGDHN 

       490        500        510        520        530        540 
RFYQTYLGQY PGNYFTGDGA KRDEDGYYWI TGRVDDVLNV SGHRLGTAEI ESALVLHPAV 

       550        560        570        580        590        600 
AEAAVVGYPH EIKGQGVYCY VTLMGNATES DELNVELREF VAKELGRFAK PDYIQWSPGL 

       610        620        630        640 
PKTRSGKIMR RILRKIAEND VDSLGDTSTL ADPSVVENLI DKRIIHGA

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References

[1]"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses."
Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. expand/collapse author list , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000083 Genomic DNA. Translation: AAZ26507.1.
RefSeqYP_270613.1. NC_003910.7.

3D structure databases

ProteinModelPortalQ47X57.
SMRQ47X57. Positions 20-643.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ47X57.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3520759.
GenomeReviewsGene locus CPS_3955 in contig CP000083_GR.
KEGGcps:CPS_3955.
NMPDRfig|167879.3.peg.3952.
PATRIC21470797. VBIColPsy94388_3583.
TIGRCPS_3955.

Phylogenomic databases

eggNOGCOG0365.
HOGENOMHBG547964.
OMADGFYWIL.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ47X57_COLP3
AccessionPrimary (citable) accession number: Q47X57
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info