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Q47W31 (UPPP_COLP3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:CPS_4342
OrganismColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]
Taxonomic identifier167879 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 272272Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000227614

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane117 – 13721Helical; Potential
Transmembrane151 – 17121Helical; Potential
Transmembrane196 – 21621Helical; Potential
Transmembrane228 – 24821Helical; Potential
Transmembrane251 – 27121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q47W31 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 394C6E4B4A423C33

FASTA27229,374
        10         20         30         40         50         60 
MSTLEIIILA LLQGLTEFLP ISSSAHLILP SQVLGWQDQG LAFDVAVHVG TLLAVMMYFR 

        70         80         90        100        110        120 
KELGVMAVAW LGTVGVGPEK GRGGFDAKLS WWILLATIPA GLFGLLGKDF IEEHLRSALV 

       130        140        150        160        170        180 
IAMTTLLFGF LLGFADIKAG KRTEHKPMEK LGLKGAMLIG LAQAVALIPG TSRSGITMTI 

       190        200        210        220        230        240 
GLMLGLSRDN AARFSFLLSI PAIAMAGSYL TLKLILSTES VDWFAMGLGS LLAFVSAYAC 

       250        260        270 
IHYFLILLEK LGMMPFVIYR LILGVGLLWF IL 

« Hide

References

[1]"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses."
Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. expand/collapse author list , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 34H / ATCC BAA-681.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000083 Genomic DNA. Translation: AAZ28219.1.
RefSeqYP_270991.1. NC_003910.7.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING167879.CPS_4342.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ28219; AAZ28219; CPS_4342.
GeneID3522478.
KEGGcps:CPS_4342.
PATRIC21471531. VBIColPsy94388_3946.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMASDIMRIA.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycCPSY167879:GI48-4343-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_COLP3
AccessionPrimary (citable) accession number: Q47W31
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families