SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q47W31

- UPPP_COLP3

UniProt

Q47W31 - UPPP_COLP3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Undecaprenyl-diphosphatase

Gene
uppP, CPS_4342
Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity.UniRule annotation

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotation

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dephosphorylation Source: InterPro
  2. peptidoglycan biosynthetic process Source: UniProtKB-KW
  3. regulation of cell shape Source: UniProtKB-KW
  4. response to antibiotic Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciCPSY167879:GI48-4343-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphatase (EC:3.6.1.27)
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:uppP
Ordered Locus Names:CPS_4342
OrganismiColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Taxonomic identifieri167879 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia
ProteomesiUP000000547: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121Helical; Reviewed predictionAdd
BLAST
Transmembranei39 – 5921Helical; Reviewed predictionAdd
BLAST
Transmembranei91 – 11121Helical; Reviewed predictionAdd
BLAST
Transmembranei117 – 13721Helical; Reviewed predictionAdd
BLAST
Transmembranei151 – 17121Helical; Reviewed predictionAdd
BLAST
Transmembranei196 – 21621Helical; Reviewed predictionAdd
BLAST
Transmembranei228 – 24821Helical; Reviewed predictionAdd
BLAST
Transmembranei251 – 27121Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 272272Undecaprenyl-diphosphataseUniRule annotationPRO_0000227614Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi167879.CPS_4342.

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
HOGENOMiHOG000218357.
KOiK06153.
OMAiSDIMRIA.
OrthoDBiEOG6QP13M.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase.
InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00753. undec_PP_bacA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q47W31-1 [UniParc]FASTAAdd to Basket

« Hide

MSTLEIIILA LLQGLTEFLP ISSSAHLILP SQVLGWQDQG LAFDVAVHVG    50
TLLAVMMYFR KELGVMAVAW LGTVGVGPEK GRGGFDAKLS WWILLATIPA 100
GLFGLLGKDF IEEHLRSALV IAMTTLLFGF LLGFADIKAG KRTEHKPMEK 150
LGLKGAMLIG LAQAVALIPG TSRSGITMTI GLMLGLSRDN AARFSFLLSI 200
PAIAMAGSYL TLKLILSTES VDWFAMGLGS LLAFVSAYAC IHYFLILLEK 250
LGMMPFVIYR LILGVGLLWF IL 272
Length:272
Mass (Da):29,374
Last modified:September 13, 2005 - v1
Checksum:i394C6E4B4A423C33
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000083 Genomic DNA. Translation: AAZ28219.1.
RefSeqiWP_011045072.1. NC_003910.7.
YP_270991.1. NC_003910.7.

Genome annotation databases

EnsemblBacteriaiAAZ28219; AAZ28219; CPS_4342.
GeneIDi3522478.
KEGGicps:CPS_4342.
PATRICi21471531. VBIColPsy94388_3946.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000083 Genomic DNA. Translation: AAZ28219.1 .
RefSeqi WP_011045072.1. NC_003910.7.
YP_270991.1. NC_003910.7.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167879.CPS_4342.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ28219 ; AAZ28219 ; CPS_4342 .
GeneIDi 3522478.
KEGGi cps:CPS_4342.
PATRICi 21471531. VBIColPsy94388_3946.

Phylogenomic databases

eggNOGi COG1968.
HOGENOMi HOG000218357.
KOi K06153.
OMAi SDIMRIA.
OrthoDBi EOG6QP13M.

Enzyme and pathway databases

BioCyci CPSY167879:GI48-4343-MONOMER.

Family and domain databases

HAMAPi MF_01006. Undec_diphosphatase.
InterProi IPR003824. UppP.
[Graphical view ]
Pfami PF02673. BacA. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00753. undec_PP_bacA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 34H / ATCC BAA-681.

Entry informationi

Entry nameiUPPP_COLP3
AccessioniPrimary (citable) accession number: Q47W31
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: September 13, 2005
Last modified: September 3, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi