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Q47VZ2 (PSD_COLP3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:CPS_4381
OrganismColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]
Taxonomic identifier167879 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 258258Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000262101
Chain259 – 29739Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000262102

Sites

Site258 – 2592Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2591Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q47VZ2 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: D74BC60DAF29A443

FASTA29732,503
        10         20         30         40         50         60 
MSSKNSLSDK IKITFQYIMP KHAISRLVGK LAAAKMGWLT TKLISMFIKA YGINMNEAKL 

        70         80         90        100        110        120 
KKASDFDTFN NFFTRELEEG ARIIDNDENT ICYPVDGAIS QQGDIIDGQL IQAKGFNYSV 

       130        140        150        160        170        180 
TSLLGGDEKT AAPFQGGKFS CIYLAPKDYH RIHMPMAATL REMIYVPGEL FSVNPLTAQN 

       190        200        210        220        230        240 
VPDLFARNER VVAIFDTEMG ELAMVLVGAT IVASIETTWA GTITPPAGKD IFRWQYPKDG 

       250        260        270        280        290 
ADAITFEKGD EMGRFKLGST VVSTFAPNMI SEFATDAGPG TVTRLGEIYA ALDKSAS

« Hide

References

[1]"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses."
Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. expand/collapse author list , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 34H / ATCC BAA-681.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000083 Genomic DNA. Translation: AAZ25919.1.
RefSeqYP_271030.1. NC_003910.7.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ47VZ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3520166.
GenomeReviewsGene locus CPS_4381 in contig CP000083_GR.
KEGGcps:CPS_4381.
NMPDRfig|167879.3.peg.4014.
PATRIC21471607. VBIColPsy94388_3984.
TIGRCPS_4381.

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG302256.
OMASMATVWH.

Enzyme and pathway databases

BioCycCPSY167879:CPS_4381-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_COLP3
AccessionPrimary (citable) accession number: Q47VZ2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: September 13, 2005
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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