Q47VY2 (GPMI_COLP3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=iPGM
EC=5.4.2.1

Gene names

Name:	gpmI
Synonyms:	gpmA
Ordered Locus Names:	CPS_4391

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]

Taxonomic identifier

167879 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia › Colwellia psychrerythraea

Protein attributes

Sequence length	520 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP-Rule MF_01038
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP-Rule MF_01038
Cofactor	Binds 2 manganese ions per subunit By similarity.
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP-Rule MF_01038
Subunit structure	Monomer By similarity.
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family.

Ontologies

Keywords
Biological process	Glycolysis
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 520	520	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP-Rule MF_01038		PRO_0000212139
Sites
	Active site	63	1	Phosphoserine intermediate By similarity
	Metal binding	13	1	Manganese 2 By similarity
	Metal binding	63	1	Manganese 2 By similarity
	Metal binding	409	1	Manganese 1 By similarity
	Metal binding	413	1	Manganese 1 By similarity
	Metal binding	450	1	Manganese 2 By similarity
	Metal binding	451	1	Manganese 2 By similarity
	Metal binding	469	1	Manganese 1 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q47VY2 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 206391609EA74823	FASTA	520	56,657
	10 20 30 40 50 60 MANKKSTVLM ILDGWGYREE TSSNAIHQAN TPVLDNLKAK YPNMLIDTSG MAVGLPEGQM 70 80 90 100 110 120 GNSEVGHVNL GAGRVVYQDF TRITKAISDG DFIENPTLCH AVDTATSNNK AVHIFGLLSP 130 140 150 160 170 180 GGVHSHEEHI FAMMELAKKR GAQKVYLHAF LDGRDTPPRS AQASLEKAQQ KFSKLFTETD 190 200 210 220 230 240 TGEGQIASVI GRYYAMDRDQ RWDRVEAAYN LMVNGEGLHQ YNSALDALAA AYERNENDEF 250 260 270 280 290 300 VGASAITSPS GKAIKVNDGD ALIFMNFRAD RARQFSRCFT DTNFNGFERK RIPAISNFVM 310 320 330 340 350 360 LTQYAADIDA PSAFAPTPLT NVMGEWLAKH NKTQLRISET EKYAHVTFFF SGGKEDMFTG 370 380 390 400 410 420 EERILVPSPD VATYDLQPEM NSTLLTDKLV GAIESGKYDF IVCNYPNGDM VGHTGSFDAA 430 440 450 460 470 480 VKACEAVDTC VGRVVKAAQD NGGECLITAD HGNAEQMQDP VSGQAHTAHT CEPVPLIYVG 490 500 510 520 RNASPAASGT LSDISPSVLH LMGMEQPQEM TGSVLMQLIK

References

[1]

"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 34H / ATCC BAA-681.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000083 Genomic DNA. Translation: AAZ25836.1.
RefSeq	YP_271040.1. NC_003910.7.
3D structure databases
ProteinModelPortal	Q47VY2.
ModBase	Search...
Protein-protein interaction databases
STRING	167879.CPS_4391.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAZ25836; AAZ25836; CPS_4391.
GeneID	3520082.
KEGG	cps:CPS_4391.
PATRIC	21471627. VBIColPsy94388_3994.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0696.
HOGENOM	HOG000223664.
KO	K15633.
OMA	NAEQMTD.
ProtClustDB	PRK05434.
Enzyme and pathway databases
BioCyc	CPSY167879:GI48-4400-MONOMER.
UniPathway	UPA00109; UER00186.
Family and domain databases
Gene3D	3.40.1450.10. 1 hit. 3.40.720.10. 2 hits.
HAMAP	MF_01038. GpmI.
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR011258. BPG-indep_PGM_N. IPR006124. Metalloenzyme. IPR005995. Pgm_bpd_ind. [Graphical view]
Pfam	PF06415. iPGM_N. 1 hit. PF01676. Metalloenzyme. 1 hit. [Graphical view]
PIRSF	PIRSF001492. IPGAM. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit. SSF64158. BPG-indep_PGM_N. 1 hit.
TIGRFAMs	TIGR01307. pgm_bpd_ind. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GPMI_COLP3

Accession

Primary (citable) accession number: Q47VY2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	September 13, 2005
Last modified:	May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program