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Protein

2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Gene

gpmI

Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.UniRule annotation

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotation

Cofactori

Mn2+UniRule annotationNote: Binds 2 manganese ions per subunit.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi13 – 131Manganese 2UniRule annotation
Active sitei63 – 631Phosphoserine intermediateUniRule annotation
Metal bindingi63 – 631Manganese 2UniRule annotation
Metal bindingi409 – 4091Manganese 1UniRule annotation
Metal bindingi413 – 4131Manganese 1UniRule annotation
Metal bindingi450 – 4501Manganese 2UniRule annotation
Metal bindingi451 – 4511Manganese 2UniRule annotation
Metal bindingi469 – 4691Manganese 1UniRule annotation

GO - Molecular functioni

  1. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Source: UniProtKB-HAMAP
  2. manganese ion binding Source: UniProtKB-HAMAP
  3. phosphoglycerate mutase activity Source: TIGR

GO - Biological processi

  1. glucose catabolic process Source: InterPro
  2. glycolytic process Source: TIGR
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciCPSY167879:GI48-4392-MONOMER.
UniPathwayiUPA00109; UER00186.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseUniRule annotation (EC:5.4.2.12UniRule annotation)
Short name:
BPG-independent PGAMUniRule annotation
Short name:
PhosphoglyceromutaseUniRule annotation
Short name:
iPGMUniRule annotation
Gene namesi
Name:gpmIUniRule annotation
Synonyms:gpmA
Ordered Locus Names:CPS_4391
OrganismiColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Taxonomic identifieri167879 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia
ProteomesiUP000000547 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 5205202,3-bisphosphoglycerate-independent phosphoglycerate mutasePRO_0000212139Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi167879.CPS_4391.

Structurei

3D structure databases

ProteinModelPortaliQ47VY2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BPG-independent phosphoglycerate mutase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0696.
HOGENOMiHOG000223664.
KOiK15633.
OMAiIENYMQE.
OrthoDBiEOG6HJ22X.

Family and domain databases

Gene3Di3.40.1450.10. 1 hit.
3.40.720.10. 2 hits.
HAMAPiMF_01038. GpmI.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR011258. BPG-indep_PGM_N.
IPR006124. Metalloenzyme.
IPR005995. Pgm_bpd_ind.
[Graphical view]
PfamiPF06415. iPGM_N. 1 hit.
PF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFiPIRSF001492. IPGAM. 1 hit.
SUPFAMiSSF53649. SSF53649. 2 hits.
SSF64158. SSF64158. 1 hit.
TIGRFAMsiTIGR01307. pgm_bpd_ind. 1 hit.

Sequencei

Sequence statusi: Complete.

Q47VY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANKKSTVLM ILDGWGYREE TSSNAIHQAN TPVLDNLKAK YPNMLIDTSG
60 70 80 90 100
MAVGLPEGQM GNSEVGHVNL GAGRVVYQDF TRITKAISDG DFIENPTLCH
110 120 130 140 150
AVDTATSNNK AVHIFGLLSP GGVHSHEEHI FAMMELAKKR GAQKVYLHAF
160 170 180 190 200
LDGRDTPPRS AQASLEKAQQ KFSKLFTETD TGEGQIASVI GRYYAMDRDQ
210 220 230 240 250
RWDRVEAAYN LMVNGEGLHQ YNSALDALAA AYERNENDEF VGASAITSPS
260 270 280 290 300
GKAIKVNDGD ALIFMNFRAD RARQFSRCFT DTNFNGFERK RIPAISNFVM
310 320 330 340 350
LTQYAADIDA PSAFAPTPLT NVMGEWLAKH NKTQLRISET EKYAHVTFFF
360 370 380 390 400
SGGKEDMFTG EERILVPSPD VATYDLQPEM NSTLLTDKLV GAIESGKYDF
410 420 430 440 450
IVCNYPNGDM VGHTGSFDAA VKACEAVDTC VGRVVKAAQD NGGECLITAD
460 470 480 490 500
HGNAEQMQDP VSGQAHTAHT CEPVPLIYVG RNASPAASGT LSDISPSVLH
510 520
LMGMEQPQEM TGSVLMQLIK
Length:520
Mass (Da):56,657
Last modified:September 13, 2005 - v1
Checksum:i206391609EA74823
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000083 Genomic DNA. Translation: AAZ25836.1.
RefSeqiYP_271040.1. NC_003910.7.

Genome annotation databases

EnsemblBacteriaiAAZ25836; AAZ25836; CPS_4391.
KEGGicps:CPS_4391.
PATRICi21471627. VBIColPsy94388_3994.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000083 Genomic DNA. Translation: AAZ25836.1.
RefSeqiYP_271040.1. NC_003910.7.

3D structure databases

ProteinModelPortaliQ47VY2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi167879.CPS_4391.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ25836; AAZ25836; CPS_4391.
KEGGicps:CPS_4391.
PATRICi21471627. VBIColPsy94388_3994.

Phylogenomic databases

eggNOGiCOG0696.
HOGENOMiHOG000223664.
KOiK15633.
OMAiIENYMQE.
OrthoDBiEOG6HJ22X.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00186.
BioCyciCPSY167879:GI48-4392-MONOMER.

Family and domain databases

Gene3Di3.40.1450.10. 1 hit.
3.40.720.10. 2 hits.
HAMAPiMF_01038. GpmI.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR011258. BPG-indep_PGM_N.
IPR006124. Metalloenzyme.
IPR005995. Pgm_bpd_ind.
[Graphical view]
PfamiPF06415. iPGM_N. 1 hit.
PF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFiPIRSF001492. IPGAM. 1 hit.
SUPFAMiSSF53649. SSF53649. 2 hits.
SSF64158. SSF64158. 1 hit.
TIGRFAMsiTIGR01307. pgm_bpd_ind. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 34H / ATCC BAA-681.

Entry informationi

Entry nameiGPMI_COLP3
AccessioniPrimary (citable) accession number: Q47VY2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: September 13, 2005
Last modified: April 1, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.