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Q47VY2 (GPMI_COLP3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=iPGM
EC=5.4.2.12
Gene names
Name:gpmI
Synonyms:gpmA
Ordered Locus Names:CPS_4391
OrganismColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]
Taxonomic identifier167879 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia

Protein attributes

Sequence length520 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP-Rule MF_01038

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP-Rule MF_01038

Cofactor

Binds 2 manganese ions per subunit By similarity. HAMAP-Rule MF_01038

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP-Rule MF_01038

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01038

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandManganese
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_function2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

manganese ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 5205202,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP-Rule MF_01038
PRO_0000212139

Sites

Active site631Phosphoserine intermediate By similarity
Metal binding131Manganese 2 By similarity
Metal binding631Manganese 2 By similarity
Metal binding4091Manganese 1 By similarity
Metal binding4131Manganese 1 By similarity
Metal binding4501Manganese 2 By similarity
Metal binding4511Manganese 2 By similarity
Metal binding4691Manganese 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q47VY2 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 206391609EA74823

FASTA52056,657
        10         20         30         40         50         60 
MANKKSTVLM ILDGWGYREE TSSNAIHQAN TPVLDNLKAK YPNMLIDTSG MAVGLPEGQM 

        70         80         90        100        110        120 
GNSEVGHVNL GAGRVVYQDF TRITKAISDG DFIENPTLCH AVDTATSNNK AVHIFGLLSP 

       130        140        150        160        170        180 
GGVHSHEEHI FAMMELAKKR GAQKVYLHAF LDGRDTPPRS AQASLEKAQQ KFSKLFTETD 

       190        200        210        220        230        240 
TGEGQIASVI GRYYAMDRDQ RWDRVEAAYN LMVNGEGLHQ YNSALDALAA AYERNENDEF 

       250        260        270        280        290        300 
VGASAITSPS GKAIKVNDGD ALIFMNFRAD RARQFSRCFT DTNFNGFERK RIPAISNFVM 

       310        320        330        340        350        360 
LTQYAADIDA PSAFAPTPLT NVMGEWLAKH NKTQLRISET EKYAHVTFFF SGGKEDMFTG 

       370        380        390        400        410        420 
EERILVPSPD VATYDLQPEM NSTLLTDKLV GAIESGKYDF IVCNYPNGDM VGHTGSFDAA 

       430        440        450        460        470        480 
VKACEAVDTC VGRVVKAAQD NGGECLITAD HGNAEQMQDP VSGQAHTAHT CEPVPLIYVG 

       490        500        510        520 
RNASPAASGT LSDISPSVLH LMGMEQPQEM TGSVLMQLIK 

« Hide

References

[1]"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses."
Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. expand/collapse author list , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.
Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 34H / ATCC BAA-681.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000083 Genomic DNA. Translation: AAZ25836.1.
RefSeqYP_271040.1. NC_003910.7.

3D structure databases

ProteinModelPortalQ47VY2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING167879.CPS_4391.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ25836; AAZ25836; CPS_4391.
GeneID3520082.
KEGGcps:CPS_4391.
PATRIC21471627. VBIColPsy94388_3994.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0696.
HOGENOMHOG000223664.
KOK15633.
OMAGVHSHIE.
OrthoDBEOG6HJ22X.
ProtClustDBPRK05434.

Enzyme and pathway databases

BioCycCPSY167879:GI48-4392-MONOMER.
UniPathwayUPA00109; UER00186.

Family and domain databases

Gene3D3.40.1450.10. 1 hit.
3.40.720.10. 2 hits.
HAMAPMF_01038. GpmI.
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR011258. BPG-indep_PGM_N.
IPR006124. Metalloenzyme.
IPR005995. Pgm_bpd_ind.
[Graphical view]
PfamPF06415. iPGM_N. 1 hit.
PF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFPIRSF001492. IPGAM. 1 hit.
SUPFAMSSF53649. SSF53649. 2 hits.
SSF64158. SSF64158. 1 hit.
TIGRFAMsTIGR01307. pgm_bpd_ind. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGPMI_COLP3
AccessionPrimary (citable) accession number: Q47VY2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: September 13, 2005
Last modified: February 19, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways