Reviewed, UniProtKB/Swiss-Prot Q47V69 (SDHD_COLP3)

Names and origin

Protein names

Recommended name:
    Probable D-serine dehydratase
    EC=4.3.1.18
Alternative name(s):
    D-serine deaminase
      Short name=DSD

Gene names

Name:	dsdA
Ordered Locus Names:	CPS_4659

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP]

Taxonomic identifier

167879 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-serine = pyruvate + NH3. HAMAP MF_01030
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the serine/threonine dehydratase family. DsdA subfamily.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	D-amino acid metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	D-serine ammonia-lyase activity Inferred from electronic annotation. Source: EC hydro-lyase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 443	443	Probable D-serine dehydratase HAMAP MF_01030		PRO_0000291724
Amino acid modifications
	Modified residue	118	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q47V69-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: CD37FF43949757BD	FASTA	443	48,450
	10 20 30 40 50 60 MNNDNIAQLI ADFPLIEKMV ELKEVSWFNP NITSLQEGLP YVGLDNNNIQ DASDRLARFA 70 80 90 100 110 120 PYMVKAFPET AITNGIIESD VVEISAMKSQ LEQQYEVEIQ GKLLLKKDSH LPISGSIKAR 130 140 150 160 170 180 GGIYEVLTHA EQLAIKAEVL ELSDDYSKLF TEEFKSFFSQ YSIAVGSTGN LGMSIGIMSA 190 200 210 220 230 240 KLGFSVSVHM SADARQWKKE KLRAHGVNVV EYNEDYSVAV EQGRQEAEND PKCFFIDDEN 250 260 270 280 290 300 SQTLFLGYSV AGERLKQQFD AMHIVVDENN PLFVYLPCGV GGGPGGVAFG LKMAFGDNVH 310 320 330 340 350 360 CIFAEPTHSP CMLLGILTGL HDGIAVQDIG IDNITAADGL AVGRASGFVG RAMERLLDGF 370 380 390 400 410 420 YTISDQRMYD LLGLLNKVEG IQLEPSALAG MLGPIVVTNN DEYLKRINMS NEKLVNATHL 430 440 IWATGGGMVP AIEMEKYLSK AGS

References

[1]

"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000083 Genomic DNA. Translation: AAZ26608.1.
RefSeq	YP_271303.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3520861.
GenomeReviews	Gene locus CPS_4659 in contig CP000083_GR.
KEGG	cps:CPS_4659.
NMPDR	fig|167879.3.peg.3937.
TIGR	CPS_4659.
Phylogenomic databases
HOGENOM	Q47V69.
OMA	Q47V69. DHPLFVY.
Enzyme and pathway databases
BioCyc	CPSY167879:CPS_4659-MON.
Family and domain databases
HAMAP	MF_01030. [Tree]
InterPro	IPR011780. D_Ser_am_lyase. IPR001926. PyrdxlP-dep_enz_bsu. IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS. [Graphical view]
PANTHER	PTHR10314:SF9. D_Ser_am_lyase. 1 hit.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
TIGRFAMs	TIGR02035. D_Ser_am_lyase. 1 hit.
PROSITE	PS00165. DEHYDRATASE_SER_THR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SDHD_COLP3

Accession

Primary (citable) accession number: Q47V69

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)