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Protein

Glutaminase

Gene

glsA

Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei69SubstrateUniRule annotation1
Binding sitei120SubstrateUniRule annotation1
Binding sitei164SubstrateUniRule annotation1
Binding sitei171SubstrateUniRule annotation1
Binding sitei195SubstrateUniRule annotation1
Binding sitei247SubstrateUniRule annotation1
Binding sitei265Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:CPS_4729
OrganismiColwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus)
Taxonomic identifieri167879 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesColwelliaceaeColwellia
Proteomesi
  • UP000000547 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000483341 – 311GlutaminaseAdd BLAST311

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi167879.CPS_4729.

Structurei

3D structure databases

ProteinModelPortaliQ47UZ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiPMNPMVN.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q47UZ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKSPQQPVI QSILDDAYHK FENDTSGKNA DYIPALAKVD SAYFGLAVVT
60 70 80 90 100
PHGKIYTKGD VSQPFSIQSI SKVFTLALAM EQKGPQTIVD KIGVNATGLA
110 120 130 140 150
FNSVTAIELN KARSVNPLVN AGAIATVSLL DGKNEKAKWS ALSAWYDKFA
160 170 180 190 200
NRKLSVLEDV YKSESDTNGH NRAIAELLTS YDRFYGDVDL NLAIYTRQCS
210 220 230 240 250
VAVTTKDLAV MASVFANNGV HPLTDKRLMS SDNVSRVLAV MTTAGLYENS
260 270 280 290 300
GQWAYQVGLP AKSGVGGGII AVSPGKFAVA VFSPRLDSAG NSIRAQKAID
310
YIAEKLHANI F
Length:311
Mass (Da):33,372
Last modified:September 13, 2005 - v1
Checksum:i1018DA985F00CAFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000083 Genomic DNA. Translation: AAZ24857.1.
RefSeqiWP_011045454.1. NC_003910.7.

Genome annotation databases

EnsemblBacteriaiAAZ24857; AAZ24857; CPS_4729.
KEGGicps:CPS_4729.
PATRICi21472273. VBIColPsy94388_4314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000083 Genomic DNA. Translation: AAZ24857.1.
RefSeqiWP_011045454.1. NC_003910.7.

3D structure databases

ProteinModelPortaliQ47UZ9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi167879.CPS_4729.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ24857; AAZ24857; CPS_4729.
KEGGicps:CPS_4729.
PATRICi21472273. VBIColPsy94388_4314.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiPMNPMVN.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_COLP3
AccessioniPrimary (citable) accession number: Q47UZ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.