Q47UK9 (Q47UK9_COLP3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malate synthase G 2 HAMAP MF_00641
EC=2.3.3.9 HAMAP MF_00641

Gene names

Name:	glcB2 HAMAP MF_00641
Ordered Locus Names:	CPS_4874

Organism

Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [Complete proteome] [HAMAP] EMBL AAZ25107.1

Taxonomic identifier

167879 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Colwellia

Protein attributes

Sequence length	729 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP MF_00641 SAAS SAAS006253
Pathway	Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP MF_00641 SAAS SAAS006253
Subunit structure	Monomer By similarity. HAMAP MF_00641 SAAS SAAS006253
Subcellular location	Cytoplasm By similarity HAMAP MF_00641.
Sequence similarities	Belongs to the malate synthase family. GlcB subfamily. HAMAP MF_00641

Ontologies

Keywords
Biological process	Glyoxylate bypass HAMAP MF_00641 SAAS SAAS006253 Tricarboxylic acid cycle HAMAP MF_00641 SAAS SAAS006253
Cellular component	Cytoplasm HAMAP MF_00641 SAAS SAAS006253
Molecular function	Transferase HAMAP MF_00641 SAAS SAAS006253
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate cycle Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	malate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	340	1	Proton acceptor By similarity HAMAP MF_00641
	Active site	637	1	Proton donor By similarity HAMAP MF_00641

Sequences

	Sequence		Length	Mass (Da)
	Q47UK9 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 8C924D50D9A94BC3	FASTA	729	81,005
	10 20 30 40 50 60 MKQRTIKHGY KVAGCLYNLV NHEVLPGLNI HADDFWNSVA EVLAEFTPRN QQLLATRANL 70 80 90 100 110 120 QAHIDVWHTD PANQPFNQQR YELFLKEIGY LVTEKADFTI STQNVDDEVA LIAGPQLVVP 130 140 150 160 170 180 LMNARFSLNA ANARWGSLYD ALYGTDVIGD DNGAKQTKDF NPIRGRRVQA YARRFLDETL 190 200 210 220 230 240 PLTRGSHIDA VKYHIVKKAF TVTLFTGEQV QLKEAQQFVG YKGSTAAPSI LLCRHNGLHI 250 260 270 280 290 300 EIQIDKDNVV GKTDAAAVKD VVLESALSTI QDCEDSIAAV DASDKTSVYR NWLGLMKGDL 310 320 330 340 350 360 AEIIQKGSRT ITRTLNHDRN YLSPDQKEIT LPGRSLQFIR NVGHLMTTNA IVTAKNEKVP 370 380 390 400 410 420 EGIVDGLITS LISLHDLKGT SKFKNSKQGS IYIVKPKMHG PEEVAFSHDL FSAIERHLGL 430 440 450 460 470 480 AQNTIKMGIM DEERRTSANL KECIRAAQTR LAFINTGFLD RTGDEIHTSM HAGAMAQKAL 490 500 510 520 530 540 MKDEPWITAY ENRNVRIGLQ AGLQGKAQIG KGMWAIPDQM SEMVKSKIAH PKSGANCAWV 550 560 570 580 590 600 PSPTAATLHV MHYHKVNVQE IQSAMQAEFS LPGTIDDLSE LLTIPLLKNQ TELSTAAIQK 610 620 630 640 650 660 ELDNNIQGLL GYVVRWVNQG IGCSKVPDID NIARMEDRAT LRISSQHVCN WLHHGVISDS 670 680 690 700 710 720 QVLESLQRMA EVVDQQNAAD SSYIAIGTDF GESIAFKAAK DLIFQGKEQP SGYTEPLLHQ RRQEVKAMY

References

[1]

"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses." Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M. , Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005) [PubMed: 16043709] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000083 Genomic DNA. Translation: AAZ25107.1.
RefSeq	YP_271513.1. NC_003910.7.
3D structure databases
ProteinModelPortal	Q47UK9.
SMR	Q47UK9. Positions 3-728.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47UK9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3518567.
GenomeReviews	Gene locus CPS_4874 in contig CP000083_GR.
KEGG	cps:CPS_4874.
NMPDR	fig|167879.3.peg.4731.
PATRIC	21472551. VBIColPsy94388_4448.
TIGR	CPS_4874.
Phylogenomic databases
eggNOG	COG2225.
HOGENOM	HBG350005.
OMA	IQIDAND.
ProtClustDB	PRK02999.
Family and domain databases
HAMAP	MF_00641. Malate_synth_G. [Tree]
InterPro	IPR011076. Malate_synth-like. IPR023310. Malate_synth_G_beta_sub_dom. IPR001465. Malate_synthase. IPR006253. Malate_synthG. [Graphical view]
Gene3D	G3DSA:2.170.170.11. Malate_synth_G_beta_sub_dom. 2 hits.
KO	K01638.
PANTHER	PTHR21631:SF1. Malate_synthase. 1 hit.
Pfam	PF01274. Malate_synthase. 1 hit. [Graphical view]
SUPFAM	SSF51645. Malat_synth_like. 1 hit.
TIGRFAMs	TIGR01345. Malate_syn_G. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q47UK9_COLP3

Accession

Primary (citable) accession number: Q47UK9

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)