Q47SG3 (Q47SG3_THEFY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-oxoglutarate dehydrogenase E1 component EMBL AAZ54604.1
EC=1.2.4.2 EMBL AAZ54604.1

Gene names

Ordered Locus Names:

Tfu_0566

Organism

Thermobifida fusca (strain YX) [Complete proteome] [HAMAP]

Taxonomic identifier

269800 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	1214 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Molecular function	Oxidoreductase EMBL AAZ54604.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: EC thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q47SG3 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: DB52AC41D6A70A6B	FASTA	1,214	134,408
	10 20 30 40 50 60 MSSEASQPLT DFGPNEWLVD ELHRKYLADP NSVDKAWWNF FADYKSGTAA DGSTSPAKST 70 80 90 100 110 120 VAGNGAGGAV RAAASKAAAR PATATTPDGS DDALAVSQER LRGASARTAA NMESSLTLPT 130 140 150 160 170 180 ATSVRAVPVK LLFDNRIVIN NHLRRARGGK VSFTHLIGYA MVKALESVPV MNYSYTEIDG 190 200 210 220 230 240 KPAVAKPKHV NFGLAIDLAK PDGSRQLVVP NIKAADTMNF KEFWSACEEL VRKARSNKLT 250 260 270 280 290 300 VADFQGTTIT LTNPGGIGTV HSVPRLMPGQ GTILGVGAME YPAEFQGASP ATLNELAVSK 310 320 330 340 350 360 VMTLTSTYDH RIIQGAESGE FLRRIHQLLL GEDGFYDEIF ESLRIPYEPV RWVQDISVNR 370 380 390 400 410 420 DNQLDKATRV QELIHAYRVR GHLMADTDPL EYKQRRHPDL DVLEHGLTLW DLDREFPTGG 430 440 450 460 470 480 FGGKPVMKLR EILGILRDSY CRTVGIEYMH IQSPEEREWI QARVEREPEK LSREEQLHIL 490 500 510 520 530 540 KLLNSAEAFE TFLQTKYVGQ KRFSLEGGES LIPLLDGVIT KAARAQLDEV VIGMAHRGRL 550 560 570 580 590 600 NVLANICGKS YAQIFGEFEG NLDPRSAHGS GDVKYHLGTE GTFTTITGEK IAISLAANPS 610 620 630 640 650 660 HLETVNPVAE GIVRAKQDIL NKGATGFTVL PILIHGDAAF AGQGVVAETL NLSQLRGYRT 670 680 690 700 710 720 GGTIHIIVNN QVGFTTSPKD SRSSVYATDV ARMVQAPIFH VNGDDPEAVV RVARLAFAYR 730 740 750 760 770 780 QEFNKDVVID LVCYRRRGHN EADNPSFTQP LMYDIIDAKR STRKLYTEAL IGRGDITLEE 790 800 810 820 830 840 AEEALRDYQE QLERAFAETR EAAKKPIEPG SVIKPEVFTE APIDHSATPT AVSEEVIKRV 850 860 870 880 890 900 AETQVTFPEG FTVHPRLLPQ LQRRVRMVEE NAIDWAMAET LAFGSLLIDG HPVRLVGQDS 910 920 930 940 950 960 RRGTFGQRHA VLVDRKTGEE YTPLKVFDRG TAKFHVHDSL LSEYAALGFE YGYSLERPDA 970 980 990 1000 1010 1020 LVAWEAQFGD FVNGAQTVID EYISSGEQKW GQKSSVTLLL PHGYEGQGPD HSSARIERFL 1030 1040 1050 1060 1070 1080 QLCAQENMTV TIPTTPANYF HLLRWQVKSP YRRPLIVFTP KSMLRHKAAV SAVSEFTSGS 1090 1100 1110 1120 1130 1140 FRPLIPDTSG IAPEDVRRVI LCAGKIYYEL DAARKRTGDQ HTAIIRVERL YPLPIDEIRQ 1150 1160 1170 1180 1190 1200 QLRSFPNAGE VLWVQEEPAN MGPWPFVALV FAEQLDRPFT RISRSASSSP ATGSAKRHEV 1210 EQQALVNTVF PPTE

References

[1]

"Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX." Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B., Kyrpides N. J. Bacteriol. 189:2477-2486(2007) [PubMed: 17209016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000088 Genomic DNA. Translation: AAZ54604.1.
RefSeq	YP_288627.1. NC_007333.1.
3D structure databases
ProteinModelPortal	Q47SG3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47SG3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3581264.
GenomeReviews	Gene locus Tfu_0566 in contig CP000088_GR.
KEGG	tfu:Tfu_0566.
NMPDR	fig|269800.4.peg.562.
PATRIC	23901562. VBITheFus33945_0586.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0567.
HOGENOM	HBG289950.
OMA	EGDEPAF.
PhylomeDB	Q47SG3.
ProtClustDB	PRK12270.
Enzyme and pathway databases
BioCyc	TFUS269800:TFU_0566-MONOMER.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
KO	K00164.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q47SG3_THEFY

Accession

Primary (citable) accession number: Q47SG3

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)