Q47SE3 (Q47SE3_THEFY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphorylase RuleBase RU000587
EC=2.4.1.1 RuleBase RU000587

Gene names

Ordered Locus Names:

Tfu_0586

Organism

Thermobifida fusca (strain YX) [Complete proteome] [HAMAP]

Taxonomic identifier

269800 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	873 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity. RuleBase RU000587
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. RuleBase RU000587
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000587
Sequence similarities	Belongs to the glycogen phosphorylase family. RuleBase RU004179

Ontologies

Keywords
Biological process	Carbohydrate metabolism RuleBase RU000587
Molecular function	Glycosyltransferase RuleBase RU000587 EMBL AAZ54624.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q47SE3 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: A3F6F648CDFD1106	FASTA	873	97,172
	10 20 30 40 50 60 MKAIRRFTVR TVLPDELAAL CTLAANLRWT WHAPTRAVFA AVEPRLWEAV GRDPIRLLGE 70 80 90 100 110 120 VTPERLRELA ADAEFRARLD AAAADLDRYL TAPLWYQQLT DSSDTPPPAA IAYFSAEYGL 130 140 150 160 170 180 DATLPQYSGG LGILAGDHLK SASDLGIPVI GVGLLYRHGY FSQTLSPDGW QLERYPEIDP 190 200 210 220 230 240 HCLPMTRLED RGTPVRITVD LPENRTLTAH VWIVRVGRVP LLLLDTYHDD NDLDLRGVTD 250 260 270 280 290 300 RLYGGGTEQR LRQELLLGIG GLRAVRAYCL RTGYPEPEVF HMNEGHAGFL GLERLREYIE 310 320 330 340 350 360 TAGLDFDQAL EATRSGTVFT THTPVPAGID RFPKELVERH FSGPVALPGL PVERVMALGA 370 380 390 400 410 420 ETYPGGDPNV FNMAVMGMRL AQRVNGVSAL HGAVSREMFG GLWPGFDVDE VPITSITNGV 430 440 450 460 470 480 HAATWMAEEA WDAAQAMGLG LEELETPAGW QRLVERDAEE LWRMRRALRE RLIIEARKRL 490 500 510 520 530 540 RASWRQRGAT DAELAWIDEA LDPEVLTVGF ARRVPSYKRL TLMLRDPERL TALLRHPERP 550 560 570 580 590 600 IQIIIAGKAH PADEGGKRLI QEMVRFSDDP RVRDRIVFLP DYDMALAALL VQGCDVWLNN 610 620 630 640 650 660 PLRPLEACGT SGMKSALNGG LNLSIRDGWW DEWFDGSNGW AIPTADGVDD PDRRDDIEAA 670 680 690 700 710 720 ALYELFEEQV APLFYERDDH GLPRRWLETV KHTMVSLGPK VQATRMVREY VDQLYQPAAL 730 740 750 760 770 780 AMRRLAADNY RGARELAAWK QRVQHAWPGV RIEHVETSMN GDTPQVGGEL EVRATLVLGG 790 800 810 820 830 840 LDPDDVCVEV VLGLVNDDDE LINPTTTELV PLPASDVVYP LVRFGGTVPL DRAGTCGYTV 850 860 870 RIRPRHRLLT HPAEAGMAVV AEPTMGIGTL VPH

References

[1]

"Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX." Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B., Kyrpides N. J. Bacteriol. 189:2477-2486(2007) [PubMed: 17209016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000088 Genomic DNA. Translation: AAZ54624.1.
RefSeq	YP_288647.1. NC_007333.1.
3D structure databases
ProteinModelPortal	Q47SE3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47SE3.
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3580160.
GenomeReviews	Gene locus Tfu_0586 in contig CP000088_GR.
KEGG	tfu:Tfu_0586.
NMPDR	fig|269800.4.peg.582.
PATRIC	23901604. VBITheFus33945_0607.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0058.
HOGENOM	HBG302557.
OMA	LRWSWHP.
PhylomeDB	Q47SE3.
Enzyme and pathway databases
BioCyc	TFUS269800:TFU_0586-MONOMER.
Family and domain databases
InterPro	IPR011834. Agluc_phsphrylas. IPR000811. Glyco_trans_35. IPR024517. Glycogen_phosphorylase_DUF3417. [Graphical view]
KO	K00688.
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF11897. DUF3417. 1 hit. PF00343. Phosphorylase. 2 hits. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02094. More_P_ylases. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q47SE3_THEFY

Accession

Primary (citable) accession number: Q47SE3

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)