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Protein

Glucanase

Gene

Tfu_0620

Organism
Thermobifida fusca (strain YX)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi180CalciumCombined sources1
Active sitei264UniRule annotation1
Active sitei312Proton donorUniRule annotation1
Metal bindingi457Calcium; via carbonyl oxygenCombined sources1
Active sitei535NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotationImported, Hydrolase
Biological processCarbohydrate metabolism, Cellulose degradationUniRule annotation, Polysaccharide degradation
LigandCalciumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyciTFUS269800:GI42-632-MONOMER.

Protein family/group databases

CAZyiCBM2. Carbohydrate-Binding Module Family 2.
GH6. Glycoside Hydrolase Family 6.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucanaseUniRule annotation (EC:3.2.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:Tfu_0620Imported
OrganismiThermobifida fusca (strain YX)Imported
Taxonomic identifieri269800 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptosporangialesNocardiopsaceaeThermobifida
Proteomesi
  • UP000000434 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33UniRule annotationAdd BLAST33
ChainiPRO_500514327534 – 596GlucanaseUniRule annotationAdd BLAST563

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi265 ↔ 330Combined sources
Disulfide bondi503 ↔ 553Combined sources

Interactioni

Protein-protein interaction databases

STRINGi269800.Tfu_0620.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4AVNX-ray2.00A177-596[»]
4AVOX-ray1.80A177-596[»]
ProteinModelPortaliQ47SA9.
SMRiQ47SA9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 142CBM2InterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the glycosyl hydrolase family 6.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG41065HY. Bacteria.
COG5297. LUCA.
HOGENOMiHOG000178851.
KOiK19668.
OMAiKCANAQS.
OrthoDBiPOG091H09LC.

Family and domain databases

Gene3Di3.20.20.40. 1 hit.
InterProiView protein in InterPro
IPR016288. Beta_cellobiohydrolase.
IPR036434. Beta_cellobiohydrolase_sf.
IPR008965. Carb-bd_dom_sf.
IPR001919. CBD2.
IPR001524. Glyco_hydro_6_CS.
IPR006311. TAT_signal.
PANTHERiPTHR34876. PTHR34876. 1 hit.
PfamiView protein in Pfam
PF00553. CBM_2. 1 hit.
PF01341. Glyco_hydro_6. 1 hit.
PIRSFiPIRSF001100. Beta_cellobiohydrolase. 1 hit.
PRINTSiPR00733. GLHYDRLASE6.
SMARTiView protein in SMART
SM00637. CBD_II. 1 hit.
SUPFAMiSSF49384. SSF49384. 1 hit.
SSF51989. SSF51989. 1 hit.
PROSITEiView protein in PROSITE
PS51173. CBM2. 1 hit.
PS00655. GLYCOSYL_HYDROL_F6_1. 1 hit.
PS51318. TAT. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q47SA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKVRATNRR SWMRRGLAAA SGLALGASMV AFAAPANAAG CSVDYTVNSW
60 70 80 90 100
GTGFTANVTI TNLGSAINGW TLEWDFPGNQ QVTNLWNGTY TQSGQHVSVS
110 120 130 140 150
NAPYNASIPA NGTVEFGFNG SYSGSNDIPS SFKLNGVTCD GSDDPDPEPS
160 170 180 190 200
PSPSPSPSPT DPDEPGGPTN PPTNPGEKVD NPFEGAKLYV NPVWSAKAAA
210 220 230 240 250
EPGGSAVANE STAVWLDRIG AIEGNDSPTT GSMGLRDHLE EAVRQSGGDP
260 270 280 290 300
LTIQVVIYNL PGRDCAALAS NGELGPDELD RYKSEYIDPI ADIMWDFADY
310 320 330 340 350
ENLRIVAIIE IDSLPNLVTN VGGNGGTELC AYMKQNGGYV NGVGYALRKL
360 370 380 390 400
GEIPNVYNYI DAAHHGWIGW DSNFGPSVDI FYEAANASGS TVDYVHGFIS
410 420 430 440 450
NTANYSATVE PYLDVNGTVN GQLIRQSKWV DWNQYVDELS FVQDLRQALI
460 470 480 490 500
AKGFRSDIGM LIDTSRNGWG GPNRPTGPSS STDLNTYVDE SRIDRRIHPG
510 520 530 540 550
NWCNQAGAGL GERPTVNPAP GVDAYVWVKP PGESDGASEE IPNDEGKGFD
560 570 580 590
RMCDPTYQGN ARNGNNPSGA LPNAPISGHW FSAQFRELLA NAYPPL
Length:596
Mass (Da):63,548
Last modified:September 13, 2005 - v1
Checksum:iB0FA5277FE7721E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000088 Genomic DNA. Translation: AAZ54658.1.
RefSeqiWP_011291067.1. NC_007333.1.

Genome annotation databases

EnsemblBacteriaiAAZ54658; AAZ54658; Tfu_0620.
KEGGitfu:Tfu_0620.

Similar proteinsi

Entry informationi

Entry nameiQ47SA9_THEFY
AccessioniPrimary (citable) accession number: Q47SA9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: November 22, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported