Q47RB8 (Q47RB8_THEFY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Ordered Locus Names:

Tfu_0961

Organism

Thermobifida fusca (strain YX) [Complete proteome] [HAMAP]

Taxonomic identifier

269800 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	373 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183 EMBL AAZ54999.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q47RB8 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 4874462515577D87	FASTA	373	38,771
	10 20 30 40 50 60 MRVGVPREIK DHEYRVAITP AGVQELVRHG HDVLIERDAG VGSAISNAEY AAAGARIIDS 70 80 90 100 110 120 ADEVWGAADL VLKVKEPVPE EYHRLRPGQV LFAYLHLAAS RDCTEALLKH GVTAIAYETV 130 140 150 160 170 180 QLPDGSLPLL APMSEIAGRL APQVGATALQ RSNGGRGVLL GGVPGVGPAK VMVLGAGVSG 190 200 210 220 230 240 MNAAQVAAGM GAEVTLLDID IAKLRRADAV FQGRVRTLAS TAYEIERTAL ESDLIIGAVL 250 260 270 280 290 300 IPGAKAPTLI SSDLVAQMKP GTVLVDIAVD QGGCFADSRP TTHSDPTYPV HNTVFYCVSN 310 320 330 340 350 360 MPGAVPTTAT QALTKDTLRY ALALANKGWR DALADDPALA AGLNTFAGEL TNEAVAQAHG 370 MAARTVTEVV AAG

References

[1]

"Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX." Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B., Kyrpides N. J. Bacteriol. 189:2477-2486(2007) [PubMed: 17209016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000088 Genomic DNA. Translation: AAZ54999.1.
RefSeq	YP_289022.1. NC_007333.1.
3D structure databases
ProteinModelPortal	Q47RB8.
SMR	Q47RB8. Positions 1-371.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47RB8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3579163.
GenomeReviews	Gene locus Tfu_0961 in contig CP000088_GR.
KEGG	tfu:Tfu_0961.
NMPDR	fig|269800.4.peg.1053.
PATRIC	23902402. VBITheFus33945_1001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0686.
HOGENOM	HBG289735.
OMA	VAHGHEV.
PhylomeDB	Q47RB8.
ProtClustDB	CLSK2769093.
Enzyme and pathway databases
BioCyc	TFUS269800:TFU_0961-MONOMER.
Family and domain databases
InterPro	IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q47RB8_THEFY

Accession

Primary (citable) accession number: Q47RB8

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)