Q47R20 (Q47R20_THEFY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydroorotate oxidase B, catalytic subunit EMBL AAZ55097.1
EC=1.3.3.1 EMBL AAZ55097.1

Gene names

Ordered Locus Names:

Tfu_1059

Organism

Thermobifida fusca (strain YX) [Complete proteome] [HAMAP]

Taxonomic identifier

269800 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor

Binds 1 FMN per subunit By similarity. SAAS SAAS012135

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis SAAS SAAS012135
Ligand	FMN SAAS SAAS012135 Flavoprotein SAAS SAAS012135
Molecular function	Oxidoreductase SAAS SAAS012135 EMBL AAZ55097.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro UMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	dihydroorotate oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	144	1	Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

	Sequence		Length	Mass (Da)
	Q47R20 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: CB4068B94D14B1EE	FASTA	330	33,629
	10 20 30 40 50 60 MPLDAETVAE TAAMIPDLRV RLGELELANP VVTAAGCAGA GRELARFFDI ARIGAVVTKS 70 80 90 100 110 120 VTVEPRAGWP APRIAETPSG VLSTVGLQGP GIDVFVQRDL PWLLSRGARA VVSVAGGSVD 130 140 150 160 170 180 EYVTLAQRLS EAPGVTAIEV NLSSPDLSRG GEHFTADPEA AAQVVAAVRE TARSDIPVFA 190 200 210 220 230 240 KLSPDVADLV ALAGKCVAAG ADGLALVNTV RGMVIDVDTM RPAVAGGMGG LSGPAIRPIA 250 260 270 280 290 300 VACVYQVHAA YPEVPIIGMG GIGTGRDALE FLLAGASAVA VGTALFHDPS ACMRVLRELE 310 320 330 RELIDRGVER VESLIGAAHH GMGGLGVAAG

References

[1]

"Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX." Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B., Kyrpides N. J. Bacteriol. 189:2477-2486(2007) [PubMed: 17209016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000088 Genomic DNA. Translation: AAZ55097.1.
RefSeq	YP_289120.1. NC_007333.1.
3D structure databases
ProteinModelPortal	Q47R20.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47R20.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3580051.
GenomeReviews	Gene locus Tfu_1059 in contig CP000088_GR.
KEGG	tfu:Tfu_1059.
NMPDR	fig|269800.4.peg.1267.
PATRIC	23902608. VBITheFus33945_1104.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0167.
HOGENOM	HBG472415.
OMA	VALRMVW.
PhylomeDB	Q47R20.
ProtClustDB	CLSK768551.
Enzyme and pathway databases
BioCyc	TFUS269800:TFU_1059-MONOMER.
Family and domain databases
HAMAP	MF_00224. DHO_dh_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR005720. Dihydroorotate_DH. IPR024920. Dihydroorotate_DH_1. IPR012135. Dihydroorotate_DH_1_2. IPR001295. Dihydroorotate_DH_CS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00226.
Pfam	PF01180. DHO_dh. 1 hit. [Graphical view]
PIRSF	PIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMs	TIGR01037. PyrD_sub1_fam. 1 hit.
PROSITE	PS00912. DHODEHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q47R20_THEFY

Accession

Primary (citable) accession number: Q47R20

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)