Q47NP7 (Q47NP7_THEFY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
EC=1.8.4.8 HAMAP MF_00063

Alternative name(s):
3'-phosphoadenylylsulfate reductase HAMAP MF_00063
PAPS reductase, thioredoxin dependent HAMAP MF_00063
PAPS sulfotransferase HAMAP MF_00063
PAdoPS reductase HAMAP MF_00063

Gene names

Name:	cysH HAMAP MF_00063
Ordered Locus Names:	Tfu_1889

Organism

Thermobifida fusca (strain YX) [Complete proteome] [HAMAP]

Taxonomic identifier

269800 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Reduction of activated sulfate into sulfite By similarity. HAMAP MF_00063 SAAS SAAS002500
Catalytic activity	Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063 SAAS SAAS002500
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063 SAAS SAAS002500
Subcellular location	Cytoplasm By similarity HAMAP MF_00063 SAAS SAAS002500.
Sequence similarities	Belongs to the PAPS reductase family. CysH subfamily. HAMAP MF_00063

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00063 SAAS SAAS002500
Molecular function	Oxidoreductase HAMAP MF_00063 SAAS SAAS002500 EMBL AAZ55922.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphoadenylyl-sulfate reductase (thioredoxin) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q47NP7 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 88C801DE06287BB1	FASTA	260	28,509
	10 20 30 40 50 60 MRPSLPPLLR RAPRRGVPPF HYDADRGGAA LNITADGAAF AAEAAARLEE ASATEIIQWA 70 80 90 100 110 120 ADTFGDRLCL TASMADAVMV DLVSKVVPGI DVIFLDTGYH FPETLGTRDA VAQTYPINLI 130 140 150 160 170 180 TVTPSRTVAE QDRDLGPRLY ARNPDLCCYL RKVEPLQRAL QSYDAWLTGL RRDEAVTRRT 190 200 210 220 230 240 VGVVQWDARK KKIKVNPIAR WTQEQVDSYI AEHGVLVNPL QDDGYPSIGC APCTQRVPEG 250 260 ADPRSGRWAG TGKVECGLHS

References

[1]

"Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX." Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B., Kyrpides N. J. Bacteriol. 189:2477-2486(2007) [PubMed: 17209016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000088 Genomic DNA. Translation: AAZ55922.1.
RefSeq	YP_289945.1. NC_007333.1.
3D structure databases
ProteinModelPortal	Q47NP7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47NP7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3579472.
GenomeReviews	Gene locus Tfu_1889 in contig CP000088_GR.
KEGG	tfu:Tfu_1889.
NMPDR	fig|269800.4.peg.2170.
PATRIC	23904394. VBITheFus33945_2031.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	FEETLAY.
PhylomeDB	Q47NP7.
ProtClustDB	PRK02090.
Enzyme and pathway databases
BioCyc	TFUS269800:TFU_1889-MONOMER.
Family and domain databases
HAMAP	MF_00063. CysH. [Tree]
InterPro	IPR004511. PAPS/APS_Rdtase. IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K00390.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMs	TIGR00434. CysH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q47NP7_THEFY

Accession

Primary (citable) accession number: Q47NP7

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)