Proteinase inhibitor I4, serpin - Thermobifida fusca (strain YX)

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Q47NK3 (Q47NK3_THEFY) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Proteinase inhibitor I4, serpin EMBL AAZ55966.1

Gene names

Ordered Locus Names:

Tfu_1933

Organism

Thermobifida fusca (strain YX) [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1SNG PDB 1MTP Complete proteome
Gene Ontology (GO)
Molecular function	serine-type endopeptidase inhibitor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q47NK3 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: A459F19B2E109207
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366

39,488

        10         20         30         40         50         60 
MSGGFLRDDH LEFALHLHRR LAEAVPDGEV IWSPYSVACA LGVLAAGARA TTRTELTTLL 

        70         80         90        100        110        120 
GTDPAPLLAA LDRAVADSPD LASRTVLWVS ADVPVRSSFR ATVHDRPDSD VRTADFRTNP 

       130        140        150        160        170        180 
EGVRATVNAD IADATRGMIR ELLPQGAVTP DLRAILTNAL WARARWTTPF EAHLTREGTF 

       190        200        210        220        230        240 
RTPRGPKRVP FMHRTGTMPY ATARGWGMVT LHAHDELAVD VLLPPGTNAA AVPTAPLLTA 

       250        260        270        280        290        300 
LHRRSASTSV ELALPRFELT QPHQLVEVLA EAGVRTLFTA SADLSGISTV PLYVDTVIHQ 

       310        320        330        340        350        360 
ARLRVDERGA EGAAATAAMM LLAGAMPPRR TIRFSVDRPF HIVVRRRGAI LFLGSIADPH 


DPGPAQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX." Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B., Kyrpides N. J. Bacteriol. 189:2477-2486(2007) [PubMed: 17209016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition." Fulton K.F., Buckle A.M., Cabrita L.D., Irving J.A., Butcher R.E., Smith I., Reeve S., Lesk A.M., Bottomley S.P., Rossjohn J., Whisstock J.C. J. Biol. Chem. 280:8435-8442(2005) [PubMed: 15590653] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.76 ANGSTROMS).
[3]	"The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment." Irving J.A., Cabrita L.D., Rossjohn J., Pike R.N., Bottomley S.P., Whisstock J.C. Structure 11:387-397(2003) [PubMed: 12679017] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 1-323 AND 324-366.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000088 Genomic DNA. Translation: AAZ55966.1.

RefSeq

YP_289989.1. NC_007333.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1MTP	X-ray	1.50	A	1-323	[»]
			B	324-366	[»]
1SNG	X-ray	1.76	A	1-366	[»]

ProteinModelPortal

SMR

Q47NK3. Positions 1-365.

ModBase

Protein-protein interaction databases

STRING

Protein family/group databases

MEROPS

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

GeneID

GenomeReviews

Gene locus Tfu_1933 in contig CP000088_GR.

KEGG

NMPDR

fig|269800.4.peg.2295.

PATRIC

23904484. VBITheFus33945_2076.

Organism-specific databases

CMR

Phylogenomic databases

eggNOG

HOGENOM

OMA

PhylomeDB

ProtClustDB

Enzyme and pathway databases

BioCyc

TFUS269800:TFU_1933-MONOMER.

Family and domain databases

InterPro

IPR000215. Protease_inhib_I4_serpin.
IPR023796. Sepin_dom.
[Graphical view]

PANTHER

PTHR11461. Prot_inh_serpin. 1 hit.

Pfam

PF00079. Serpin. 1 hit.
[Graphical view]

SMART

SM00093. SERPIN. 1 hit.
[Graphical view]

SUPFAM

SSF56574. Prot_inh_serpin. 1 hit.

ProtoNet

Entry information

Entry name

Q47NK3_THEFY

Accession

Primary (citable) accession number: Q47NK3

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info