Q47L91 (Q47L91_THEFY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Ordered Locus Names:

Tfu_2748

Organism

Thermobifida fusca (strain YX) [Complete proteome] [HAMAP]

Taxonomic identifier

269800 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	350 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370 SAAS SAAS004733
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371 SAAS SAAS004733
Subcellular location	Cytoplasm By similarity SAAS SAAS004733.
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS004733
Cellular component	Cytoplasm SAAS SAAS004733
Ligand	ATP-binding SAAS SAAS004733 Nucleotide-binding
Molecular function	Ligase RuleBase RU004370 SAAS SAAS004733 EMBL AAZ56781.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q47L91 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 9B1838F28FA743EE	FASTA	350	36,158
	10 20 30 40 50 60 MSERAPTAYA AAGVDIAAGE RAVELMKRHV ARTHRPELVP DASGFAGLFR LDLSKYTAPV 70 80 90 100 110 120 LATSTDGVGT KVMLAQALDR HDTIGIDLVA MVVDDLVVSG AEPLFLTDYI ACGSVVPERI 130 140 150 160 170 180 AEIVSGIAEG CCQAGCTLIG GETAEHPGAM GPDEYDLAGA GTGIVEADAI LGPDRVRVGD 190 200 210 220 230 240 VVIAMASSGP HSNGYSLIRR IVADAQLDLH ANVPELGGPL GEVLLTPTRI YAKDCLALAA 250 260 270 280 290 300 DMEVHAFAHI TGGGLAANLA RSLPATADAV VDRASWAPPA VFGFLARHGQ VSQEDMEATF 310 320 330 340 350 NMGVGMVAIV AEDAAERALE LLAERGVPAW VLGSVIPGSG KVVMTGEYRS

References

[1]

"Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX." Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B., Kyrpides N. J. Bacteriol. 189:2477-2486(2007) [PubMed: 17209016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000088 Genomic DNA. Translation: AAZ56781.1.
RefSeq	YP_290804.1. NC_007333.1.
3D structure databases
ProteinModelPortal	Q47L91.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47L91.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3579226.
GenomeReviews	Gene locus Tfu_2748 in contig CP000088_GR.
KEGG	tfu:Tfu_2748.
NMPDR	fig|269800.4.peg.2884.
PATRIC	23906248. VBITheFus33945_2930.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0150.
HOGENOM	HBG531222.
OMA	PENIPRV.
PhylomeDB	Q47L91.
ProtClustDB	PRK05385.
Enzyme and pathway databases
BioCyc	TFUS269800:TFU_2748-MONOMER.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q47L91_THEFY

Accession

Primary (citable) accession number: Q47L91

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)