Q47KH1 (PATR_THEFY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Ordered Locus Names:	Tfu_3018

Organism

Thermobifida fusca (strain YX) [Complete proteome] [HAMAP]

Taxonomic identifier

269800 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptosporangineae › Nocardiopsaceae › Thermobifida

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: InterPro histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 359	359	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_0000153522
Amino acid modifications
	Modified residue	223	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q47KH1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 9B07005CB3F997CE	FASTA	359	38,920
	10 20 30 40 50 60 MSERKPPYLR SALDSIPPYR PGRKVVGPDG RSAKLSSNES PFGPLPSVRQ AIADAAADLN 70 80 90 100 110 120 RYPDPAAAEL TAALARRFHV PEEHVALGAG SVGLLQQLLE ATAEPGAEVV YAWRSFEAYP 130 140 150 160 170 180 LLTGLAGATP IHVPLREETH DLEALAAAVT DRTRMVFVCN PNNPTGTAVR ETELAEFLDT 190 200 210 220 230 240 VPEHVLVVLD EAYREYVQDP RVPDGVQLYR DRPNVAVLRT FSKAYGLAAL RVGFLIGHPQ 250 260 270 280 290 300 VVDAVRKTLV PFAVNHLAQA AAVASLAAEQ ELLERVAVTV KERERVRAAL LADGWTVPET 310 320 330 340 350 EANFVWLRLG EDTLDFAAAC EQAGIAVRPF AGEGVRVSIG LPDDNDAFLT VARTYPKRN

References

[1]

"Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX." Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M., DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A., Richardson P., Wilson D.B., Kyrpides N. J. Bacteriol. 189:2477-2486(2007) [PubMed: 17209016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YX.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000088 Genomic DNA. Translation: AAZ57051.1.
RefSeq	YP_291074.1. NC_007333.1.
3D structure databases
ProteinModelPortal	Q47KH1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47KH1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3579258.
GenomeReviews	Gene locus Tfu_3018 in contig CP000088_GR.
KEGG	tfu:Tfu_3018.
NMPDR	fig|269800.4.peg.3011.
PATRIC	23906810. VBITheFus33945_3211.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0079.
HOGENOM	HBG646350.
OMA	NNTKIVW.
PhylomeDB	Q47KH1.
ProtClustDB	PRK03321.
Enzyme and pathway databases
BioCyc	TFUS269800:TFU_3018-MONOMER.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001176. ACC_synthase. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTS	PR00753. ACCSYNTHASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_THEFY

Accession

Primary (citable) accession number: Q47KH1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program