Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q47K62 (Q47K62_DECAR) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Glutathione synthetase HAMAP-Rule MF_00162

EC=6.3.2.3 HAMAP-Rule MF_00162
Alternative name(s):
GSH synthetase HAMAP-Rule MF_00162
Glutathione synthase HAMAP-Rule MF_00162
Gene names
Name:gshB HAMAP-Rule MF_00162
Ordered Locus Names:Daro_0010 EMBL AAZ44769.1
OrganismDechloromonas aromatica (strain RCB) [Complete proteome] [HAMAP] EMBL AAZ44769.1
Taxonomic identifier159087 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeDechloromonas

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione. HAMAP-Rule MF_00162

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. HAMAP-Rule MF_00162

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2. HAMAP-Rule MF_00162

Sequence similarities

Belongs to the prokaryotic GSH synthase family. HAMAP-Rule MF_00162

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00162

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain148 – 333186ATP-grasp By similarity HAMAP-Rule MF_00162
Nucleotide binding174 – 23057ATP By similarity HAMAP-Rule MF_00162

Sites

Metal binding3041Magnesium or manganese By similarity HAMAP-Rule MF_00162
Metal binding3061Magnesium or manganese By similarity HAMAP-Rule MF_00162

Sequences

Sequence LengthMass (Da)Tools
Q47K62 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 9452134D7DE364B4

FASTA33937,643
        10         20         30         40         50         60 
MAQQLHFEKH LLGGSSQSLK LAFVLDPLDH LKAWKDSSVA MMRAAEKHGH EVFAIDAATL 

        70         80         90        100        110        120 
GWRKPDDAHA GGISGEALHL HLRPDDHDWY RETGREWMPL TAFDAVIMRK DPPFDFEYLT 

       130        140        150        160        170        180 
ATWLLERAEA DGVRVFNRPR ALRDHSEKLA IMEFAHFAPA TAISRDMAQI HHFIDEQRDV 

       190        200        210        220        230        240 
ILKPLDGMGG SQIFRVHRND PNRNVIVETL THEGARTIMA QRYVPEISQG DKRILLIAGK 

       250        260        270        280        290        300 
PVPWCLARIP KAGETRGNLA VGGTGVAQEL SARDLEIAET LGPILFKRGL MLVGIDVIGN 

       310        320        330 
FLTEINVTSP TCMVEIRQQS GFDAAGAFIT AIEHACGLS 

« Hide

References

[1]"Complete sequence of Dechloromonas aromatica RCB."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S., Kellar K., Schmutz J., Larimer F., Land M., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RCB.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000089 Genomic DNA. Translation: AAZ44769.1.
RefSeqYP_283239.1. NC_007298.1.

3D structure databases

ProteinModelPortalQ47K62.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING159087.Daro_0010.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ44769; AAZ44769; Daro_0010.
GeneID3570034.
KEGGdar:Daro_0010.
PATRIC21598588. VBIDecAro89105_0010.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0189.
HOGENOMHOG000265022.
KOK01920.
OMADWKIARA.
OrthoDBEOG6WMHWB.

Enzyme and pathway databases

BioCycDARO159087:GI5B-10-MONOMER.
UniPathwayUPA00142; UER00210.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00162. GSH_S.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR006284. Glut_synth_pro.
IPR004218. GSHS_ATP-bd.
IPR004215. GSHS_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PfamPF02955. GSH-S_ATP. 1 hit.
PF02951. GSH-S_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01380. glut_syn. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ47K62_DECAR
AccessionPrimary (citable) accession number: Q47K62
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)