dcd

Functionⁱ

Catalytic activityⁱ

dCTP + H₂O = dUTP + NH₃.UniRule annotation

Pathwayⁱ: dUMP biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes dUMP from dCTP (dUTP route).UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:

dCTP deaminase (dcd)
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dut)

This subpathway is part of the pathway dUMP biosynthesis, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes dUMP from dCTP (dUTP route), the pathway dUMP biosynthesis and in Pyrimidine metabolism.

GO - Molecular functionⁱ

dCTP deaminase activity Source: UniProtKB-EC

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

dUMP biosynthetic process Source: UniProtKB-UniPathway
dUTP biosynthetic process Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Hydrolase
Biological process	Nucleotide metabolism

Enzyme and pathway databases

BioCycⁱ	DARO159087:G1G4R-595-MONOMER.
UniPathwayⁱ	UPA00610; UER00665.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: dCTP deaminaseUniRule annotation (EC:3.5.4.13UniRule annotation) Alternative name(s): Deoxycytidine triphosphate deaminaseUniRule annotation
Gene namesⁱ	Name:dcdUniRule annotation Ordered Locus Names:Daro_0577
Organismⁱ	Dechloromonas aromatica (strain RCB)
Taxonomic identifierⁱ	159087 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Azonexaceae › Dechloromonas › Dechloromonas aromatica
Proteomesⁱ	UP000000550 Componentⁱ: Chromosome

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_1000009714	1 – 188	dCTP deaminaseAdd BLAST		188

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	159087.Daro_0577.

STRINGⁱ

159087.Daro_0577.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q47IJ7.
SMRⁱ	Q47IJ7.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the dCTP deaminase family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105DHP. Bacteria. COG0717. LUCA.
HOGENOMⁱ	HOG000228600.
KEGG Orthology (KO) More...KOⁱ	K01494.
OMAⁱ	GQLCLFR.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H02A6.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd07557. trimeric_dUTPase. 1 hit.
Gene3Dⁱ	2.70.40.10. 1 hit.
HAMAPⁱ	MF_00146. dCTP_deaminase. 1 hit.
InterProⁱ	View protein in InterPro IPR011962. dCTP_deaminase. IPR029054. dUTPase-like. IPR036157. dUTPase-like_sf. IPR033704. dUTPase_trimeric.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00692. dUTPase. 1 hit.
SUPFAMⁱ	SSF51283. SSF51283. 1 hit.
TIGRFAMsⁱ	TIGR02274. dCTP_deam. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q47IJ7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTIKSDKWIR RMAAEHGMIE PFSPELVREA NGQKIVSYGT SSYGYDIRCA 
        60         70         80         90        100
REFKVFTNIN STVVDPKNFD PKSFVEIESD VCIIPPNSFA LARTMEYFRI 
       110        120        130        140        150
PRSVLTVCLG KSTYARCGII VNVTPFEPEW EGHVTLEFSN TTPLPAKIYA 
       160        170        180 
GEGCAQVLFF ESDEICETSY KDRGGKYQGQ EGVTLPKI

Length:188

Mass (Da):21,158

Last modified:September 13, 2005 - v1

Checksum:ⁱCB0BDE8C0295E3FF

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000089 Genomic DNA. Translation: AAZ45334.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011286343.1. NC_007298.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAZ45334; AAZ45334; Daro_0577.
KEGGⁱ	dar:Daro_0577.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q47IJ7	A0A1Q3VQE3 C6XCR4 A0A0K0SUX4 A0A0Q6BLR0 A0A1G8IFQ5 A0A1G8ZIE4 UPI00036A9370 UPI00036BC709 UPI00048CC5FD UPI0008241B8F +8	Candidatus Accumulibacter sp. 66-26 Methylovorus glucosetrophus (strain SIP3-4) Methylophilus sp. TWE2 Methylophilus sp. Leaf416 Propionivibrio dicarboxylicus Methylophilus rhizosphaerae Methylophilus methylotrophus (Bacterium W3A1) Methylophilus Methylophilus sp. 5 Methylophilales bacterium LSUCC0135 And more	188	UniRef90_Q47IJ7	Cluster: dCTP deaminase	19

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q47IJ7	Q9ZE77 D5AVZ2 G4KLZ0 A0A1Q2SSM2 UPI0002FC0407 Q68XU3 A0A1C3EYJ4 A0A249E1E3 Q4UNF3 A0A0F3MU02 +599	Rickettsia prowazekii (strain Madrid E) Rickettsia prowazekii (strain Rp22) Rickettsia japonica (strain ATCC VR-1363 / YH) Rickettsia japonica Rickettsia typhi (strain ATCC VR-144 / Wilmington) Rickettsia sp. wb Rickettsia sp. MEAM1 (Bemisia tabaci) Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) Rickettsia felis str. Pedreira Rickettsia asembonensis And more	188	UniRef50_Q9ZE77	Cluster: dCTP deaminase	610

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000089 Genomic DNA. Translation: AAZ45334.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011286343.1. NC_007298.1.

3D structure databases

ProteinModelPortalⁱ	Q47IJ7.
SMRⁱ	Q47IJ7.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	159087.Daro_0577.

STRINGⁱ

159087.Daro_0577.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAZ45334; AAZ45334; Daro_0577.
KEGGⁱ	dar:Daro_0577.

Phylogenomic databases

eggNOGⁱ	ENOG4105DHP. Bacteria. COG0717. LUCA.
HOGENOMⁱ	HOG000228600.
KEGG Orthology (KO) More...KOⁱ	K01494.
OMAⁱ	GQLCLFR.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H02A6.

Enzyme and pathway databases

UniPathwayⁱ	UPA00610; UER00665.
BioCycⁱ	DARO159087:G1G4R-595-MONOMER.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd07557. trimeric_dUTPase. 1 hit.
Gene3Dⁱ	2.70.40.10. 1 hit.
HAMAPⁱ	MF_00146. dCTP_deaminase. 1 hit.
InterProⁱ	View protein in InterPro IPR011962. dCTP_deaminase. IPR029054. dUTPase-like. IPR036157. dUTPase-like_sf. IPR033704. dUTPase_trimeric.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00692. dUTPase. 1 hit.
SUPFAMⁱ	SSF51283. SSF51283. 1 hit.
TIGRFAMsⁱ	TIGR02274. dCTP_deam. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	DCD_DECAR
Accessionⁱ	Q47IJ7Primary (citable) accession number: Q47IJ7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
	Last sequence update:	September 13, 2005
	Last modified:	February 28, 2018
	This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB - Q47IJ7 (DCD_DECAR)

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dCTP deaminase

Select a section on the left to see content.

Functionⁱ

Catalytic activityⁱ

Pathwayⁱ: dUMP biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

PTM / Processingⁱ

Molecule processing

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q47IJ7 (DCD_DECAR)

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dCTP deaminase

dcd

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: dUMP biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

Pathwayⁱ: dUMP biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ