Q47IJ7 (DCD_DECAR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Daro_0577

Organism

Dechloromonas aromatica (strain RCB) [Complete proteome] [HAMAP]

Taxonomic identifier

159087 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Dechloromonas › Dechloromonas aromatica

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: UniProtKB-HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000009714

Sequences

	Sequence		Length	Mass (Da)
	Q47IJ7 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: CB0BDE8C0295E3FF	FASTA	188	21,158
	10 20 30 40 50 60 MTIKSDKWIR RMAAEHGMIE PFSPELVREA NGQKIVSYGT SSYGYDIRCA REFKVFTNIN 70 80 90 100 110 120 STVVDPKNFD PKSFVEIESD VCIIPPNSFA LARTMEYFRI PRSVLTVCLG KSTYARCGII 130 140 150 160 170 180 VNVTPFEPEW EGHVTLEFSN TTPLPAKIYA GEGCAQVLFF ESDEICETSY KDRGGKYQGQ EGVTLPKI

References

[1]

"Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation." Salinero K.K., Keller K., Feil W.S., Feil H., Trong S., Di Bartolo G., Lapidus A. BMC Genomics 10:351-351(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RCB.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000089 Genomic DNA. Translation: AAZ45334.1.
RefSeq	YP_283804.1. NC_007298.1.
3D structure databases
ProteinModelPortal	Q47IJ7.
ModBase	Search...
MobiDB	Search...
Protein-protein interaction databases
STRING	159087.Daro_0577.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAZ45334; AAZ45334; Daro_0577.
GeneID	3568803.
KEGG	dar:Daro_0577.
PATRIC	21599768. VBIDecAro89105_0584.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228600.
KO	K01494.
OMA	MEYFRIP.
OrthoDB	EOG67DPKR.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	DARO159087:GI5B-594-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_DECAR

Accession

Primary (citable) accession number: Q47IJ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	February 19, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program