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Q47GP8 (UBIG_DECAR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-demethylubiquinone-9 3-methyltransferase

EC=2.1.1.64
Alternative name(s):
2-polyprenyl-6-hydroxyphenyl methylase
EC=2.1.1.222
3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase
Short name=DHHB methyltransferase
Gene names
Name:ubiG
Ordered Locus Names:Daro_1227
OrganismDechloromonas aromatica (strain RCB) [Complete proteome] [HAMAP]
Taxonomic identifier159087 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeDechloromonas

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Non-specific O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway By similarity.

Catalytic activity

S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n. HAMAP MF_00472

S-adenosyl-L-methionine + 3-(all-trans-polyprenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-polyprenyl)phenol.

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_00472

Sequence similarities

Belongs to the methyltransferase superfamily. UbiG/COQ3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2322323-demethylubiquinone-9 3-methyltransferase HAMAP MF_00472
PRO_0000241708

Sequences

Sequence LengthMass (Da)Tools
Q47GP8 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: E8D09C6AE2B4C954

FASTA23225,806
        10         20         30         40         50         60 
MLNADQAELD KFGELAHRWW DPNSEFKPLH DINPLRIDWI DQAISLAGKR VLDVGCGGGL 

        70         80         90        100        110        120 
LSEGMAVRGA NVTGIDLSEK PLGVAKLHLL ETGQKVDYRK ISVEELAEQM PGEFDAVTCL 

       130        140        150        160        170        180 
EMLEHVPNPS SVITACARLV KPGGQVFLST LNRNPKSYLF AVIGAEYVLQ MLPKGTHDYA 

       190        200        210        220        230 
RFIKPSELAR WAKMANLEPE ELVGMSYNPL TKKYSLGKDT SVNYLMRTIR HV 

« Hide

References

[1]"Complete sequence of Dechloromonas aromatica RCB."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S., Kellar K., Schmutz J., Larimer F., Land M., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RCB.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000089 Genomic DNA. Translation: AAZ45983.1.
RefSeqYP_284453.1. NC_007298.1.

3D structure databases

ProteinModelPortalQ47GP8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ47GP8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3569411.
GenomeReviewsGene locus Daro_1227 in contig CP000089_GR.
KEGGdar:Daro_1227.
NMPDRfig|159087.4.peg.891.
PATRIC21601106. VBIDecAro89105_1228.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2227.
HOGENOMHBG738842.
OMADHAEIAK.
PhylomeDBQ47GP8.
ProtClustDBPRK05134.

Enzyme and pathway databases

BioCycDARO159087:DARO_1227-MONOMER.

Family and domain databases

HAMAPMF_00472. UbiG.
[Tree]
InterProIPR013216. Methyltransf_11.
IPR010233. UbiG_MeTrfase.
[Graphical view]
KOK00568.
PANTHERPTHR23134. PTHR23134. 1 hit.
PfamPF08241. Methyltransf_11. 1 hit.
[Graphical view]
TIGRFAMsTIGR01983. UbiG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUBIG_DECAR
AccessionPrimary (citable) accession number: Q47GP8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: September 13, 2005
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families