Q47EU6 (MSRB_DECAR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB
EC=1.8.4.12

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Ordered Locus Names:	Daro_1889

Organism

Dechloromonas aromatica (strain RCB) [Complete proteome] [HAMAP]

Taxonomic identifier

159087 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Dechloromonas

Protein attributes

Sequence length	132 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity.
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 132	132	Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400		PRO_1000068268
Sites
	Active site	119	1	Nucleophile By similarity
	Metal binding	47	1	Zinc By similarity
	Metal binding	50	1	Zinc By similarity
	Metal binding	96	1	Zinc By similarity
	Metal binding	99	1	Zinc By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q47EU6 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: CDCC06237E57F113	FASTA	132	14,991
	10 20 30 40 50 60 MPKIEKTDAE WRAQLDENEY RVTRQKGTER AFTGKYWDTH DDGTYRCICC GAPLFRSETK 70 80 90 100 110 120 FDSGCGWPSF HTPNDEKLID EHVDQSFGMI RTEVTCHDCG AHLGHVFDDG PAPTGLRYCI 130 NSASLKLEKD GK

References

[1]

"Complete sequence of Dechloromonas aromatica RCB." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S., Kellar K., Schmutz J., Larimer F., Land M., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RCB.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000089 Genomic DNA. Translation: AAZ46635.1.
RefSeq	YP_285105.1. NC_007298.1.
3D structure databases
ProteinModelPortal	Q47EU6.
SMR	Q47EU6. Positions 3-129.
ModBase	Search...
Protein-protein interaction databases
STRING	Q47EU6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3569604.
GenomeReviews	Gene locus Daro_1889 in contig CP000089_GR.
KEGG	dar:Daro_1889.
NMPDR	fig|159087.4.peg.1900.
PATRIC	21602434. VBIDecAro89105_1878.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0229.
HOGENOM	HBG715255.
OMA	APLFRSD.
PhylomeDB	Q47EU6.
Enzyme and pathway databases
BioCyc	DARO159087:DARO_1889-MONOMER.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_DECAR

Accession

Primary (citable) accession number: Q47EU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program