ID   MHPF_DECAR              Reviewed;         314 AA.
AC   Q47B12;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Acetaldehyde dehydrogenase;
DE            EC=1.2.1.10;
DE   AltName: Full=Acetaldehyde dehydrogenase [acetylating];
GN   Name=mhpF; OrderedLocusNames=Daro_3239;
OS   Dechloromonas aromatica (strain RCB).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Rhodocyclaceae; Dechloromonas.
OX   NCBI_TaxID=159087;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S., Kellar K.,
RA   Schmutz J., Larimer F., Land M., Ivanova N., Richardson P.;
RT   "Complete sequence of Dechloromonas aromatica RCB.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the terminal reaction in meta-cleavage
CC       pathways, that is, the transformation of acetaldehyde into acetyl
CC       coenzyme A (By similarity).
CC   -!- CATALYTIC ACTIVITY: Acetaldehyde + CoA + NAD(+) = acetyl-CoA +
CC       NADH.
CC   -!- PATHWAY: Aromatic compound metabolism; 3-phenylpropionic acid
CC       degradation.
CC   -!- SIMILARITY: Belongs to the acetaldehyde dehydrogenase family. MhpF
CC       subfamily.
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DR   EMBL; CP000089; AAZ47969.1; -; Genomic_DNA.
DR   RefSeq; YP_286439.1; -.
DR   SMR; Q47B12; 1-313.
DR   GeneID; 3566585; -.
DR   GenomeReviews; CP000089_GR; Daro_3239.
DR   KEGG; dar:Daro_3239; -.
DR   NMPDR; fig|159087.4.peg.3778; -.
DR   HOGENOM; Q47B12; -.
DR   OMA; Q47B12; KEIDIVF.
DR   BioCyc; DARO159087:DARO_3239-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0008774; F:acetaldehyde dehydrogenase (acetylating) ac...; IEA:HAMAP.
DR   GO; GO:0051287; F:NAD or NADH binding; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_01657; -; 1.
DR   InterPro; IPR003361; Acetaldehyde_dehydrogenase.
DR   InterPro; IPR015426; Acetylaldehyde_DH_C.
DR   InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR   PANTHER; PTHR21123; Acetylald_dh; 1.
DR   Pfam; PF09290; AcetDehyd-dimer; 1.
DR   Pfam; PF01118; Semialdhyde_dh; 1.
DR   PIRSF; PIRSF015689; Actaldh_dh_actl; 1.
DR   TIGRFAMs; TIGR03215; ac_ald_DH_ac; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism; Complete proteome; NAD;
KW   Oxidoreductase.
FT   CHAIN         1    314       Acetaldehyde dehydrogenase.
FT                                /FTId=PRO_0000337978.
SQ   SEQUENCE   314 AA;  33113 MW;  BA1845382DFE9832 CRC64;
     MNKKLKVAII GPGNIGTDLM IKIMRHGEHL EMGAMVGIDP QSDGLARAQR MGVATTHEGV
     EGLTRLPVFA DIDIVFDATS AGAHVRNDAF LRSLKPNIRM VDLTPAAIGP YCIPVVNGAA
     HDEALNVNMV TCGGQATIPM VAAVSRVAKV HYGEIIASIS SKSAGPGTRA NIDEFTETTS
     KAIEAVGGAA KGKAIIILNP AEPPLIMRDT VYCLSELVDE DEIAASVAQM AADVQKYVPG
     YRLKQKVQFD IIPASRPINI PGVGQRMSGL KTSVFLEVEG AAHYLPAYAG NLDIMTSAAK
     TTAERMAARI LSAA
//