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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Dechloromonas aromatica (strain RCB)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei95L-glutamineUniRule annotation1
Binding sitei244L-glutamineUniRule annotation1
Binding sitei263ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi63 – 65ATPUniRule annotation3
Nucleotide bindingi298 – 299ATPUniRule annotation2
Nucleotide bindingi306 – 308ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationSAAS annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:Daro_3447Imported
OrganismiDechloromonas aromatica (strain RCB)Imported
Taxonomic identifieri159087 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesAzonexaceaeDechloromonas
Proteomesi
  • UP000000550 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi159087.Daro_3447.

Structurei

3D structure databases

ProteinModelPortaliQ47AF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 371tRNA-synt_1cInterPro annotationAdd BLAST317
Domaini379 – 576tRNA-synt_1c_CInterPro annotationAdd BLAST198

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi305 – 309"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_N.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q47AF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPNQPANT PAPAANFIKN IVEADLAAGK HAQRHWAGHP GTAADHAAAP
60 70 80 90 100
LDPAKLRTRF PPEPNGYLHF GHAKSILLNF GLAEQYGGRC HLRFDDTNPE
110 120 130 140 150
KEDQEYVDSI VDAVKWLGCS WEKDGEANLY YASNYFDWML QCAEALIAAG
160 170 180 190 200
HAYVDSQNAE EMRANRGTLT QPGKNSPFRD RSVAENMDLF KRMQAGEFAD
210 220 230 240 250
GAHILRARID MAAPNINLRD PAIYRIRHAT HHNTGDKYCV YPMYTFAHPI
260 270 280 290 300
EDALENITHS ICTLEFEDQR PFYDWLLERL AEAGLLQRPL PQQIEFSRLN
310 320 330 340 350
LTYVVLSKRK LIQLVEEKHV TGWDDPRMPT LVGARRRGYS AEGFRLFADR
360 370 380 390 400
IGVSKNDSLI DYVLFEDAMR EVMNESDLRR IAVLDPVKLI IDNYPDGQVE
410 420 430 440 450
ECFAPNHPLH PELGQRSIPF SRELWIEGED FMEVPSKGFR RLFPGNMARL
460 470 480 490 500
RYGYVVECTG CDKDENGKVI AVHCNYLPET KSGTPGADSV KVKGNLHWVS
510 520 530 540 550
AAQSYQAEIR LYERLFKVPA PGARREGDAP DLERDFLDDM NTDSAKTITA
560 570 580 590 600
QLEPCLRDAK PEERFQFERH GYFVADRVDS KPGAPVFNRA VTLKDSWGKA

S
Length:601
Mass (Da):67,998
Last modified:September 13, 2005 - v1
Checksum:i178B8638DC75F8B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000089 Genomic DNA. Translation: AAZ48176.1.
RefSeqiWP_011289172.1. NC_007298.1.

Genome annotation databases

EnsemblBacteriaiAAZ48176; AAZ48176; Daro_3447.
KEGGidar:Daro_3447.

Similar proteinsi

Entry informationi

Entry nameiQ47AF5_DECAR
AccessioniPrimary (citable) accession number: Q47AF5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: November 22, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported