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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Dechloromonas aromatica (strain RCB)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei308 – 3081ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutaminyl-tRNA aminoacylation Source: InterPro
  2. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotation, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciDARO159087:GI5B-3522-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotationSAAS annotation (EC:6.1.1.18UniRule annotationSAAS annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:Daro_3447Imported
OrganismiDechloromonas aromatica (strain RCB)Imported
Taxonomic identifieri159087 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeDechloromonas
ProteomesiUP000000550 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi159087.Daro_3447.

Structurei

3D structure databases

ProteinModelPortaliQ47AF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi305 – 3095"KMSKS" regionUniRule annotation

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiEOG6DRPF7.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth.
InterProiIPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q47AF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPNQPANT PAPAANFIKN IVEADLAAGK HAQRHWAGHP GTAADHAAAP
60 70 80 90 100
LDPAKLRTRF PPEPNGYLHF GHAKSILLNF GLAEQYGGRC HLRFDDTNPE
110 120 130 140 150
KEDQEYVDSI VDAVKWLGCS WEKDGEANLY YASNYFDWML QCAEALIAAG
160 170 180 190 200
HAYVDSQNAE EMRANRGTLT QPGKNSPFRD RSVAENMDLF KRMQAGEFAD
210 220 230 240 250
GAHILRARID MAAPNINLRD PAIYRIRHAT HHNTGDKYCV YPMYTFAHPI
260 270 280 290 300
EDALENITHS ICTLEFEDQR PFYDWLLERL AEAGLLQRPL PQQIEFSRLN
310 320 330 340 350
LTYVVLSKRK LIQLVEEKHV TGWDDPRMPT LVGARRRGYS AEGFRLFADR
360 370 380 390 400
IGVSKNDSLI DYVLFEDAMR EVMNESDLRR IAVLDPVKLI IDNYPDGQVE
410 420 430 440 450
ECFAPNHPLH PELGQRSIPF SRELWIEGED FMEVPSKGFR RLFPGNMARL
460 470 480 490 500
RYGYVVECTG CDKDENGKVI AVHCNYLPET KSGTPGADSV KVKGNLHWVS
510 520 530 540 550
AAQSYQAEIR LYERLFKVPA PGARREGDAP DLERDFLDDM NTDSAKTITA
560 570 580 590 600
QLEPCLRDAK PEERFQFERH GYFVADRVDS KPGAPVFNRA VTLKDSWGKA

S
Length:601
Mass (Da):67,998
Last modified:September 13, 2005 - v1
Checksum:i178B8638DC75F8B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000089 Genomic DNA. Translation: AAZ48176.1.
RefSeqiYP_286646.1. NC_007298.1.

Genome annotation databases

EnsemblBacteriaiAAZ48176; AAZ48176; Daro_3447.
KEGGidar:Daro_3447.
PATRICi21605568. VBIDecAro89105_3427.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000089 Genomic DNA. Translation: AAZ48176.1.
RefSeqiYP_286646.1. NC_007298.1.

3D structure databases

ProteinModelPortaliQ47AF5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi159087.Daro_3447.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ48176; AAZ48176; Daro_3447.
KEGGidar:Daro_3447.
PATRICi21605568. VBIDecAro89105_3427.

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiEOG6DRPF7.

Enzyme and pathway databases

BioCyciDARO159087:GI5B-3522-MONOMER.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth.
InterProiIPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation."
    Salinero K.K., Keller K., Feil W.S., Feil H., Trong S., Di Bartolo G., Lapidus A.
    BMC Genomics 10:351-351(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RCBImported.

Entry informationi

Entry nameiQ47AF5_DECAR
AccessioniPrimary (citable) accession number: Q47AF5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: April 1, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.