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Q479X4 (F16A2_DECAR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1 2
Short name=FBPase class 1 2
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2
Gene names
Name:fbp2
Ordered Locus Names:Daro_3628
OrganismDechloromonas aromatica (strain RCB) [Complete proteome] [HAMAP]
Taxonomic identifier159087 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Dechloromonas

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm Potential HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 357357Fructose-1,6-bisphosphatase class 1 2 HAMAP MF_01855
PRO_0000364535

Regions

Region115 – 1184Substrate binding By similarity

Sites

Metal binding901Magnesium 1 By similarity
Metal binding1121Magnesium 1 By similarity
Metal binding1121Magnesium 2 By similarity
Metal binding1141Magnesium 1; via carbonyl oxygen By similarity
Metal binding1151Magnesium 2 By similarity
Metal binding2781Magnesium 2 By similarity
Binding site2061Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q479X4 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: FF8DF124A1FDD963

FASTA35739,185
        10         20         30         40         50         60 
MQFGRTTLSK FVIENTRASH GELGALLIDV AAAVKTISAM VAKGALAGHH GALDSTNVQG 

        70         80         90        100        110        120 
EVQKKLDVLT NDAILRHCEW GGQLAGMASE EMDDPYPIPA EYPRGRYLLV FDPLDGSSNS 

       130        140        150        160        170        180 
DVNVSVGTIF SIFSRRAAGD AELGDYLRPG SEQVAAGYAI YGPSTMMVLT LGNGTHGFTL 

       190        200        210        220        230        240 
DRESGNFILT HANIRVPEDT REFAINTSNE RFWEPPVQRY VSECKAGKSG VRGEDFNTRW 

       250        260        270        280        290        300 
IASMVAEVHR ILIRGGIFMY PKDSKDPSKP GRLRLLYEAN PMAMLIEQAG GAASTGRQRI 

       310        320        330        340        350 
LDVVPDSLHQ RAPVILGSKN EVERLARYHH EYDTGADRPF VSPLFSERSL FRDESRA

« Hide

References

[1]"Complete sequence of Dechloromonas aromatica RCB."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S., Kellar K., Schmutz J., Larimer F., Land M., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RCB.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000089 Genomic DNA. Translation: AAZ48357.1.
RefSeqYP_286827.1. NC_007298.1.

3D structure databases

HSSPHSSP built from PDB template 1LEV based on UniProtKB P00636.
ProteinModelPortalQ479X4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ479X4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3567994.
GenomeReviewsGene locus Daro_3628 in contig CP000089_GR.
KEGGdar:Daro_3628.
NMPDRfig|159087.4.peg.3078.
PATRIC21605938. VBIDecAro89105_3611.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0158.
HOGENOMHBG731261.
OMAVMVYTTG.
PhylomeDBQ479X4.
ProtClustDBPRK09293.

Enzyme and pathway databases

BioCycDARO159087:DARO_3628-MONOMER.

Family and domain databases

HAMAPMF_01855. FBPase_class1.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF16A2_DECAR
AccessionPrimary (citable) accession number: Q479X4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: September 13, 2005
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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