Reviewed, UniProtKB/Swiss-Prot Q479T3 (HEM6_DECAR)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3

Gene names

Name:	hemF
Ordered Locus Names:	Daro_3669

Organism

Dechloromonas aromatica (strain RCB) [Complete proteome] [HAMAP]

Taxonomic identifier

159087 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Rhodocyclales › Rhodocyclaceae › Dechloromonas

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O. HAMAP MF_00333
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1. HAMAP MF_00333
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 298	298	Coproporphyrinogen III oxidase, aerobic HAMAP MF_00333		PRO_1000019467

Sequences

	Sequence		Length	Mass (Da)
	Q479T3-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: BB21B8689491EB94	FASTA	298	34,231
	10 20 30 40 50 60 MDTTRLKDFF TGLQSRIVAE LEAFDGQPFR TDSWVRPEGG GGISRLIEEG DFFERGGVNF 70 80 90 100 110 120 SHVTGKSLPA SATAVRPQLA GRSWEAMGVS LVLHPRNPYC PTAHMNVRCF VASKEGEEDV 130 140 150 160 170 180 WWFGGGMDMT PYYGQREDVV HFHQTCKDAL APFGDEVYPK YKHWCDEYFF LKHRNEPRGV 190 200 210 220 230 240 GGVFFDDLNE GGFERCFELT QAVGNAFTKA YLPVLAKRRE MPYDERERDF QAYRRGRYVE 250 260 270 280 290 FNLVWDRGTL FGLQSGGRTE SILMSLPPIV KWRYDWQPEA GSPEAELYEV FLKPQDWA

References

[1]

"Complete sequence of Dechloromonas aromatica RCB." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S., Kellar K., Schmutz J., Larimer F., Land M., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000089 Genomic DNA. Translation: AAZ48398.1.
RefSeq	YP_286868.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3566781.
GenomeReviews	Gene locus Daro_3669 in contig CP000089_GR.
KEGG	dar:Daro_3669.
NMPDR	fig|159087.4.peg.3191.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q479T3.
Enzyme and pathway databases
BioCyc	DARO159087:DARO_3669-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_DECAR

Accession

Primary (citable) accession number: Q479T3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	November 4, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)