Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Catalase-peroxidase

Gene

katG

Organism
Dechloromonas aromatica (strain RCB)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei93Transition state stabilizerUniRule annotation1
Active sitei97Proton acceptorUniRule annotation1
Metal bindingi265Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciDARO159087:G1G4R-3959-MONOMER

Protein family/group databases

PeroxiBasei2367 DarCP01_RCB

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
Ordered Locus Names:Daro_3836
OrganismiDechloromonas aromatica (strain RCB)
Taxonomic identifieri159087 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesAzonexaceaeDechloromonas
Proteomesi
  • UP000000550 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003547661 – 736Catalase-peroxidaseAdd BLAST736

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki96 ↔ 224Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-250)UniRule annotation
Cross-linki224 ↔ 250Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-96)UniRule annotation

Post-translational modificationi

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Proteomic databases

PRIDEiQ479B7

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi159087.Daro_3836

Structurei

3D structure databases

ProteinModelPortaliQ479B7
SMRiQ479B7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1X Bacteria
COG0376 LUCA
HOGENOMiHOG000218110
KOiK03782
OMAiPEEDIYW
OrthoDBiPOG091H05R1

Family and domain databases

HAMAPiMF_01961 Catal_peroxid, 1 hit
InterProiView protein in InterPro
IPR000763 Catalase_peroxidase
IPR010255 Haem_peroxidase
IPR002016 Haem_peroxidase_pln/fun/bac
IPR019794 Peroxidases_AS
PANTHERiPTHR30555 PTHR30555, 1 hit
PfamiView protein in Pfam
PF00141 peroxidase, 2 hits
PRINTSiPR00460 BPEROXIDASE
PR00458 PEROXIDASE
SUPFAMiSSF48113 SSF48113, 2 hits
TIGRFAMsiTIGR00198 cat_per_HPI, 1 hit
PROSITEiView protein in PROSITE
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit

Sequencei

Sequence statusi: Complete.

Q479B7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNEQKCPFS GTHGARTTVG TQSNRDWWPK VLNLNILHQH APAANPMDAD
60 70 80 90 100
FDYSETFKTL DFGALKQDLY ALMTTSQDWW PADWGHYGGL FIRMAWHSAG
110 120 130 140 150
TYRTGDGRGG AGTGNQRFAP INSWPDNGNL DKARRLLWPI KQKYGNKISW
160 170 180 190 200
ADLMILAGNC ALESMGFKTF GFGGGRVDIW QPEEDIYWGA EREWLATSDK
210 220 230 240 250
PNSRYSGERN LDNPLAAVQM GLIYVNPEGP DGNPDPVASG RDIRETFARM
260 270 280 290 300
AMNDEETVAL TAGGHTFGKA HGAGDPALVG PEPEAAPIEE QGLGWINKFG
310 320 330 340 350
SGKGIHATTS GIEGAWKPNP TKWDNGYFDM LFGYEWELTR SPAGAKQWVA
360 370 380 390 400
KDCKPEHLIP DAHDPSKKHP PMMTTADLAM RFDPIYGPIS RRFHQDPAAF
410 420 430 440 450
ADAFARAWFK LTHRDLGPKA RYLGPEVPAE DLVWQDPIPA VDHPLIEVTD
460 470 480 490 500
VASLKAKLLA SGLSTAELVS TAWASASTFR GSDKRGGANG ARIRLAPQKD
510 520 530 540 550
WAANQPAQLA KVLGVLEGIQ QAFNSAQTGG KKVSLADLIV LGGCAAVEAA
560 570 580 590 600
AKAAGFAVAV PFTPGRTDAS QEQTDAESIA VLEPEADGFR NYQKKTYSVS
610 620 630 640 650
AEEMLVDKAQ LLTLSAPEMT VLVGGLRVLG GNVGGSSDGV FTTTPGTLSN
660 670 680 690 700
DFFVNLLDMG TVWKPAAESA GRYEGRDRQT GVAKWTASRV DLIFGSNSQL
710 720 730
RALAEVYAQN DAQEKFVRDF IAAWSKVMEL DRFDLK
Length:736
Mass (Da):80,014
Last modified:September 13, 2005 - v1
Checksum:i7D3C0F3432884025
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000089 Genomic DNA Translation: AAZ48564.1
RefSeqiWP_011289559.1, NC_007298.1

Genome annotation databases

EnsemblBacteriaiAAZ48564; AAZ48564; Daro_3836
KEGGidar:Daro_3836

Similar proteinsi

Entry informationi

Entry nameiKATG_DECAR
AccessioniPrimary (citable) accession number: Q479B7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: September 13, 2005
Last modified: February 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health