ID   APAH_DECAR              Reviewed;         276 AA.
AC   Q478S1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase, symmetrical;
DE            EC=3.6.1.41;
DE   AltName: Full=Diadenosine tetraphosphatase;
DE   AltName: Full=Ap4A hydrolase;
DE   AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase;
GN   Name=apaH; OrderedLocusNames=Daro_3932;
OS   Dechloromonas aromatica (strain RCB).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Rhodocyclales;
OC   Rhodocyclaceae; Dechloromonas.
OX   NCBI_TaxID=159087;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S., Kellar K.,
RA   Schmutz J., Larimer F., Land M., Ivanova N., Richardson P.;
RT   "Complete sequence of Dechloromonas aromatica RCB.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to
CC       yield ADP (By similarity).
CC   -!- CATALYTIC ACTIVITY: P(1),P(4)-bis(5'-adenosyl) tetraphosphate +
CC       H(2)O = 2 ADP.
CC   -!- SIMILARITY: Belongs to the Ap4A hydrolase family.
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DR   EMBL; CP000089; AAZ48660.1; -; Genomic_DNA.
DR   RefSeq; YP_287130.1; -.
DR   GeneID; 3567663; -.
DR   GenomeReviews; CP000089_GR; Daro_3932.
DR   KEGG; dar:Daro_3932; -.
DR   NMPDR; fig|159087.4.peg.3019; -.
DR   HOGENOM; Q478S1; -.
DR   OMA; Q478S1; LVFGHWA.
DR   BioCyc; DARO159087:DARO_3932-MON; -.
DR   GO; GO:0008803; F:bis(5'-nucleosyl)-tetraphosphatase (symmetr...; IEA:HAMAP.
DR   HAMAP; MF_00199; -; 1.
DR   InterPro; IPR004617; ApaH.
DR   InterPro; IPR004843; M-pesterase.
DR   InterPro; IPR006186; T_phtase_apaH.
DR   PANTHER; PTHR11668; T_phtase_apaH; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   PIRSF; PIRSF000903; B5n-ttraPtase_sm; 1.
DR   TIGRFAMs; TIGR00668; apaH; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    276       Bis(5'-nucleosyl)-tetraphosphatase,
FT                                symmetrical.
FT                                /FTId=PRO_1000012056.
SQ   SEQUENCE   276 AA;  30613 MW;  22367D1346D055C2 CRC64;
     MATYAIGDIQ GCYDSLQRLL ERCAFDPASD RLWLVGDLVN RGPKSLATLR LIKSLGPAAL
     TVLGNHDLYL LMVAEGGAKF RGKDDTLQEI LDAPDCAELL DWLRHQPICH TEGEYCLVHA
     GLLPQWTASR ARELAREVEI TLQGPDFREF ILNLWGSEPA GWSDNLSGWA RLRVIVNAMT
     RMRFCTLDGV MEFKVKGKLS NAPAGHIPWF DLPDRKSAKS VLVTGHWSAL GLKVTPNLLA
     LDSGCLWGGH LTAVRLEDRQ VFQVDCSPTE ALPLKR
//