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Q478S1 (APAH_DECAR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

EC=3.6.1.41
Alternative name(s):
Ap4A hydrolase
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase
Diadenosine tetraphosphatase
Gene names
Name:apaH
Ordered Locus Names:Daro_3932
OrganismDechloromonas aromatica (strain RCB) [Complete proteome] [HAMAP]
Taxonomic identifier159087 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesRhodocyclaceaeDechloromonas

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP By similarity. HAMAP MF_00199

Catalytic activity

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP. HAMAP MF_00199

Sequence similarities

Belongs to the Ap4A hydrolase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionbis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Bis(5'-nucleosyl)-tetraphosphatase, symmetrical HAMAP MF_00199
PRO_1000012056

Sequences

Sequence LengthMass (Da)Tools
Q478S1 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 22367D1346D055C2

FASTA27630,613
        10         20         30         40         50         60 
MATYAIGDIQ GCYDSLQRLL ERCAFDPASD RLWLVGDLVN RGPKSLATLR LIKSLGPAAL 

        70         80         90        100        110        120 
TVLGNHDLYL LMVAEGGAKF RGKDDTLQEI LDAPDCAELL DWLRHQPICH TEGEYCLVHA 

       130        140        150        160        170        180 
GLLPQWTASR ARELAREVEI TLQGPDFREF ILNLWGSEPA GWSDNLSGWA RLRVIVNAMT 

       190        200        210        220        230        240 
RMRFCTLDGV MEFKVKGKLS NAPAGHIPWF DLPDRKSAKS VLVTGHWSAL GLKVTPNLLA 

       250        260        270 
LDSGCLWGGH LTAVRLEDRQ VFQVDCSPTE ALPLKR 

« Hide

References

[1]"Complete sequence of Dechloromonas aromatica RCB."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Di Bartolo G., Trong S., Kellar K., Schmutz J., Larimer F., Land M., Ivanova N., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RCB.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000089 Genomic DNA. Translation: AAZ48660.1.
RefSeqYP_287130.1. NC_007298.1.

3D structure databases

ProteinModelPortalQ478S1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ478S1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3567663.
GenomeReviewsGene locus Daro_3932 in contig CP000089_GR.
KEGGdar:Daro_3932.
NMPDRfig|159087.4.peg.3019.
PATRIC21606558. VBIDecAro89105_3919.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0639.
HOGENOMHBG724457.
OMALVFGHWA.
PhylomeDBQ478S1.
ProtClustDBPRK00166.

Enzyme and pathway databases

BioCycDARO159087:DARO_3932-MONOMER.

Family and domain databases

HAMAPMF_00199. ApaH.
[Tree]
InterProIPR004617. ApaH.
IPR004843. Metallo_PEstase_dom.
[Graphical view]
KOK01525.
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFPIRSF000903. B5n-ttraPtase_sm. 1 hit.
TIGRFAMsTIGR00668. ApaH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPAH_DECAR
AccessionPrimary (citable) accession number: Q478S1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families