ID   TR2M_PANAY              Reviewed;         562 AA.
AC   Q47861;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   20-JAN-2009, entry version 39.
DE   RecName: Full=Tryptophan 2-monooxygenase;
DE            EC=1.13.12.3;
GN   Name=iaaM;
OS   Pantoea agglomerans pv. gypsophilae (Erwinia herbicola).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Pantoea.
OX   NCBI_TaxID=48984;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PD713;
RA   Gafni Y., Manulis S., Kunik T., Lichter A.L., Barash I.B., Ophir Y.;
RT   "Characterization of the auxin synthesis genes of Erwinia herbicola
RT   pv. gypsophilae.";
RL   Isr. J. Plant Sci. 45:279-284(1997).
CC   -!- CATALYTIC ACTIVITY: L-tryptophan + O(2) = (indol-3-yl)acetamide +
CC       CO(2) + H(2)O.
CC   -!- PATHWAY: Plant hormone metabolism; auxin biosynthesis.
CC   -!- SIMILARITY: Belongs to the tryptophan 2-monooxygenase family.
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DR   EMBL; L33867; AAC17187.1; -; Genomic_DNA.
DR   BRENDA; 1.13.12.3; 298829.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0050361; F:tryptophan 2-monooxygenase activity; IEA:EC.
DR   GO; GO:0009851; P:auxin biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000759; Adrndx_reductase.
DR   InterPro; IPR002937; Amino_oxidase.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   PRINTS; PR00419; ADXRDTASE.
PE   3: Inferred from homology;
KW   Auxin biosynthesis; Monooxygenase; Oxidoreductase.
FT   CHAIN         1    562       Tryptophan 2-monooxygenase.
FT                                /FTId=PRO_0000065589.
SQ   SEQUENCE   562 AA;  62513 MW;  621E7AA389DDF886 CRC64;
     MKPHSVFADS LWPSIDLLYD YAPFLQQSMV DGHIGFFPTG ITPPRVAIIG AGISGLIAAT
     ELLRAGVRDI TLFEARDRLG GRAWSQLFDP HYYPRLIAEM GAMRFPPSAT GLFHYLNRFS
     IQTSASFPDP GIVDTELHYR GVRHLWPAGE QPPALFTRVH NGWRALLYEG CLLDGVSLVG
     PLQITAMLKS ERFDEAAEAW QIWLNVFRDC SFYSAMVTIF TGTNPPGGIA WERRDDFELF
     GALGIGSGGF LPVYQAGFTE ILRMVINGYE DDQRLIIGGI STLAEQLARQ EIRGTTPGRH
     VRFSKVNRIS KDNGKISLAT DVKPVDAFDR VIVTSNNRAM QMVHGLSADE TFLNQDVCRA
     VRETHLTGSS KLFMLTRDKF WLKNKLPLTI QSDGLVRGVY VLDYESDNPE GRGVVLLSYT
     WEDDAHKLLA ITDKKQRGQH LVDELSAIHP EFARYLVPAG ADYERYVLHH DWLTDPCSAG
     AFKLNYPGED VYSQRLFFQF KTANHPEQDS GLLLAGCGCS FTGGWVEGAV QTAVNSACAV
     IRSTGGTLYG NPLDSVHSIY DY
//