Reviewed, UniProtKB/Swiss-Prot Q47861 (TR2M_PANAY)

Names and origin

Protein names

Recommended name:
    Tryptophan 2-monooxygenase
    EC=1.13.12.3

Gene names

Name:

iaaM

Organism

Pantoea agglomerans pv. gypsophilae (Erwinia herbicola)

Taxonomic identifier

48984 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pantoea

Protein attributes

Sequence length	562 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-tryptophan + O2 = (indol-3-yl)acetamide + CO2 + H2O.
Pathway	Plant hormone metabolism; auxin biosynthesis.
Sequence similarities	Belongs to the tryptophan 2-monooxygenase family.

Ontologies

Keywords
Biological process	Auxin biosynthesis
Molecular function	Monooxygenase Oxidoreductase
Gene Ontology (GO)
Biological process	auxin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	tryptophan 2-monooxygenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 562	562	Tryptophan 2-monooxygenase		PRO_0000065589

Sequences

	Sequence		Length	Mass (Da)
	Q47861-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 621E7AA389DDF886	FASTA	562	62,513
	10 20 30 40 50 60 MKPHSVFADS LWPSIDLLYD YAPFLQQSMV DGHIGFFPTG ITPPRVAIIG AGISGLIAAT 70 80 90 100 110 120 ELLRAGVRDI TLFEARDRLG GRAWSQLFDP HYYPRLIAEM GAMRFPPSAT GLFHYLNRFS 130 140 150 160 170 180 IQTSASFPDP GIVDTELHYR GVRHLWPAGE QPPALFTRVH NGWRALLYEG CLLDGVSLVG 190 200 210 220 230 240 PLQITAMLKS ERFDEAAEAW QIWLNVFRDC SFYSAMVTIF TGTNPPGGIA WERRDDFELF 250 260 270 280 290 300 GALGIGSGGF LPVYQAGFTE ILRMVINGYE DDQRLIIGGI STLAEQLARQ EIRGTTPGRH 310 320 330 340 350 360 VRFSKVNRIS KDNGKISLAT DVKPVDAFDR VIVTSNNRAM QMVHGLSADE TFLNQDVCRA 370 380 390 400 410 420 VRETHLTGSS KLFMLTRDKF WLKNKLPLTI QSDGLVRGVY VLDYESDNPE GRGVVLLSYT 430 440 450 460 470 480 WEDDAHKLLA ITDKKQRGQH LVDELSAIHP EFARYLVPAG ADYERYVLHH DWLTDPCSAG 490 500 510 520 530 540 AFKLNYPGED VYSQRLFFQF KTANHPEQDS GLLLAGCGCS FTGGWVEGAV QTAVNSACAV 550 560 IRSTGGTLYG NPLDSVHSIY DY

References

[1]	"Characterization of the auxin synthesis genes of Erwinia herbicola pv. gypsophilae." Gafni Y., Manulis S., Kunik T., Lichter A.L., Barash I.B., Ophir Y. Isr. J. Plant Sci. 45:279-284(1997) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: PD713.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L33867 Genomic DNA. Translation: AAC17187.1.
3D structure databases
SMR	Q47861. Positions 30-547.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.13.12.3. 298829.
Family and domain databases
InterPro	IPR000759. Adrndx_reductase. IPR002937. Amino_oxidase. [Graphical view]
Pfam	PF01593. Amino_oxidase. 1 hit. [Graphical view]
PRINTS	PR00419. ADXRDTASE.
ProtoNet	Search...

Entry information

Entry name

TR2M_PANAY

Accession

Primary (citable) accession number: Q47861

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	January 19, 2010
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)