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Q477G9

- Q477G9_CUPPJ

UniProt

Q477G9 - Q477G9_CUPPJ

Protein

Tyrosine recombinase XerC

Gene

xerC

Organism
Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei158 – 1581UniRule annotation
    Active sitei193 – 1931UniRule annotation
    Active sitei267 – 2671UniRule annotation
    Active sitei270 – 2701UniRule annotation
    Active sitei293 – 2931UniRule annotation
    Active sitei302 – 3021O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. tyrosine-based site-specific recombinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. chromosome segregation Source: UniProtKB-HAMAP
    4. transposition, DNA-mediated Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotationSAAS annotation, Chromosome partitionUniRule annotationSAAS annotation, DNA integrationUniRule annotationSAAS annotation, DNA recombinationUniRule annotationSAAS annotation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCPIN264198:GIW3-82-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tyrosine recombinase XerCUniRule annotation
    Gene namesi
    Name:xerCUniRule annotation
    Ordered Locus Names:Reut_A0082Imported
    OrganismiCupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))Imported
    Taxonomic identifieri264198 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
    ProteomesiUP000002697: Chromosome 1

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi264198.Reut_A0082.

    Structurei

    3D structure databases

    ProteinModelPortaliQ477G9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the 'phage' integrase family. XerC subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG4973.
    HOGENOMiHOG000045294.
    KOiK03733.
    OMAiHVRVEKR.
    OrthoDBiEOG6PZXFP.

    Family and domain databases

    Gene3Di1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPiMF_01808. Recomb_XerC.
    InterProiIPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR011931. Recomb_XerC.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view]
    PfamiPF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56349. SSF56349. 1 hit.
    TIGRFAMsiTIGR02224. recomb_XerC. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q477G9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPAEPTNGVT NDPIVQRYLA WLEGSRKLAG HTISSYRRDL TVLQAHAAKH    50
    APGIALLALQ TRHIRAFAAR MHGEGLAGTS IARTLSAWRG FYLWAAQHGL 100
    GVQANPVDGV RAPRSGHRLP KALSVEHAVA LVSHPAGTDA AALRDQAVWE 150
    LFYSSGLRLA ELVQLDVRYE RLDGYESAGW LDLSGAELTV TGKGSRRRTV 200
    PVGSKAMEAL RAWLGVREQL LRPGAAPEDA SALFLGARGH RLSMRVVQMR 250
    LKQQAIRAGV PADVHPHMLR HSFATHMLQS SGDLRAVQEL LGHASIATTQ 300
    IYTSLDFQHL AKVYDKAHPR AGRAAPSKDG SDDDETSGD 339
    Length:339
    Mass (Da):36,755
    Last modified:September 13, 2005 - v1
    Checksum:i6E508B89327AD4FE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000090 Genomic DNA. Translation: AAZ59464.1.
    RefSeqiYP_294308.1. NC_007347.1.

    Genome annotation databases

    EnsemblBacteriaiAAZ59464; AAZ59464; Reut_A0082.
    GeneIDi3611148.
    KEGGireu:Reut_A0082.
    PATRICi20225595. VBIRalEut24049_0676.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000090 Genomic DNA. Translation: AAZ59464.1 .
    RefSeqi YP_294308.1. NC_007347.1.

    3D structure databases

    ProteinModelPortali Q477G9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 264198.Reut_A0082.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAZ59464 ; AAZ59464 ; Reut_A0082 .
    GeneIDi 3611148.
    KEGGi reu:Reut_A0082.
    PATRICi 20225595. VBIRalEut24049_0676.

    Phylogenomic databases

    eggNOGi COG4973.
    HOGENOMi HOG000045294.
    KOi K03733.
    OMAi HVRVEKR.
    OrthoDBi EOG6PZXFP.

    Enzyme and pathway databases

    BioCyci CPIN264198:GIW3-82-MONOMER.

    Family and domain databases

    Gene3Di 1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPi MF_01808. Recomb_XerC.
    InterProi IPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR011931. Recomb_XerC.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view ]
    Pfami PF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56349. SSF56349. 1 hit.
    TIGRFAMsi TIGR02224. recomb_XerC. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Ralstonia eutropha JMP134."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
      Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JMP134 / LMG 1197Imported.

    Entry informationi

    Entry nameiQ477G9_CUPPJ
    AccessioniPrimary (citable) accession number: Q477G9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 13, 2005
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3