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Reviewed, UniProtKB/Swiss-Prot Q47679 (YAFV_ECOLI)

Last modified November 24, 2009. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    UPF0012 hydrolase yafV
    EC=3.5.-.-
Gene names
Name: yafV
Ordered Locus Names: b0219, JW5019
OrganismEscherichia coli (strain K12) [Complete proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the UPF0012 family.

Contains 1 CN hydrolase domain.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processnitrogen compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256UPF0012 hydrolase yafV
PRO_0000213257

Regions

Domain4 – 256253CN hydrolase

Sites

Active site421Proton acceptor Potential
Active site1071 By similarity
Active site1411Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q47679-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 7C2381648065660C

FASTA25628,925
        10         20         30         40         50         60 
MPGLKITLLQ QPLVWMDGPA NLRHFDRQLE GITGRDVIVL PEMFTSGFAM EAAASSLAQD 

        70         80         90        100        110        120 
DVVNWMTAKA QQCNALIAGS VALQTESGSV NRFLLVEPGG TVHFYDKRHL FRMADEHLHY 

       130        140        150        160        170        180 
KAGNARVIVE WRGWRILPLV CYDLRFPVWS RNLNDYDLAL YVANWPAPRS LHWQALLTAR 

       190        200        210        220        230        240 
AIENQAYVAG CNRVGSDGNG CHYRGDSRVI NPQGEIIATA DAHQATRIDA ELSMAALREY 

       250 
REKFPAWQDA DEFRLW 

« Hide

References

[1]"Systematic sequencing of the Escherichia coli genome: analysis of the 4.0 - 6.0 min (189,987 - 281,416bp) region."
Takemoto K., Mori H., Murayama N., Kataoka K., Yano M., Itoh T., Yamamoto Y., Inokuchi H., Miki T., Hatada E., Fukuda R., Ichihara S., Mizuno T., Makino K., Nakata A., Yura T., Sampei G., Mizobuchi K.
Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"Sequence of minutes 4-25 of Escherichia coli."
Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases

U70214 Genomic DNA. Translation: AAB08641.1.
U00096 Genomic DNA. Translation: AAC73323.1.
AP009048 Genomic DNA. Translation: BAA77889.2.
PIRD64746.
RefSeqAP_000874.1.
NP_414754.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ47679.

Genome annotation databases

GeneID946585.
GenomeReviewsGene locus JW5019 in contig AP009048_GR.
Gene locus b0219 in contig U00096_GR.
KEGGecj:JW5019.
eco:b0219.

Organism-specific databases

EchoBASEEB3118.
EcoGeneEG13334. yafV.
CMRSearch...

Phylogenomic databases

HOGENOMQ47679.
OMAWHDREAN

Enzyme and pathway databases

BioCycEcoCyc:G6103-MON.
ECOL168927:B0219-MON.

Gene expression databases

GenevestigatorQ47679.

Family and domain databases

InterProIPR003010. Ntlse/CNhydtse.
IPR001110. UPF0012_CS.
[Graphical view]
Gene3DG3DSA:3.60.110.10. Ntlse/CNhydtse. 1 hit.
PfamPF00795. CN_hydrolase. 1 hit.
[Graphical view]
PROSITEPS50263. CN_HYDROLASE. 1 hit.
PS01227. UPF0012. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYAFV_ECOLI
AccessionPrimary (citable) accession number: Q47679
Secondary accession number(s): Q9R2E1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 24, 2009
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents