Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Hydrolase YafV

Gene

yafV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei42Proton acceptorPROSITE-ProRule annotation1
Active sitei107Proton donorPROSITE-ProRule annotation1
Active sitei141NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciEcoCyc:G6103-MONOMER.
ECOL316407:JW5019-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrolase YafV (EC:3.5.-.-)
Gene namesi
Name:yafV
Ordered Locus Names:b0219, JW5019
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13334. yafV.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002132571 – 256Hydrolase YafVAdd BLAST256

Proteomic databases

PaxDbiQ47679.
PRIDEiQ47679.

Interactioni

Protein-protein interaction databases

BioGridi4261824. 6 interactors.
DIPiDIP-11225N.
STRINGi511145.b0219.

Structurei

3D structure databases

ProteinModelPortaliQ47679.
SMRiQ47679.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 256CN hydrolasePROSITE-ProRule annotationAdd BLAST253

Sequence similaritiesi

Contains 1 CN hydrolase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105CZ7. Bacteria.
COG0388. LUCA.
HOGENOMiHOG000222700.
InParanoidiQ47679.
OMAiYKAGNER.
PhylomeDBiQ47679.

Family and domain databases

Gene3Di3.60.110.10. 1 hit.
InterProiIPR003010. C-N_Hydrolase.
IPR001110. UPF0012_CS.
[Graphical view]
PfamiPF00795. CN_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56317. SSF56317. 1 hit.
PROSITEiPS50263. CN_HYDROLASE. 1 hit.
PS01227. UPF0012. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q47679-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGLKITLLQ QPLVWMDGPA NLRHFDRQLE GITGRDVIVL PEMFTSGFAM
60 70 80 90 100
EAAASSLAQD DVVNWMTAKA QQCNALIAGS VALQTESGSV NRFLLVEPGG
110 120 130 140 150
TVHFYDKRHL FRMADEHLHY KAGNARVIVE WRGWRILPLV CYDLRFPVWS
160 170 180 190 200
RNLNDYDLAL YVANWPAPRS LHWQALLTAR AIENQAYVAG CNRVGSDGNG
210 220 230 240 250
CHYRGDSRVI NPQGEIIATA DAHQATRIDA ELSMAALREY REKFPAWQDA

DEFRLW
Length:256
Mass (Da):28,925
Last modified:November 1, 1996 - v1
Checksum:i7C2381648065660C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70214 Genomic DNA. Translation: AAB08641.1.
U00096 Genomic DNA. Translation: AAC73323.1.
AP009048 Genomic DNA. Translation: BAA77889.2.
PIRiD64746.
RefSeqiNP_414754.1. NC_000913.3.
WP_001118036.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73323; AAC73323; b0219.
BAA77889; BAA77889; BAA77889.
GeneIDi946585.
KEGGiecj:JW5019.
eco:b0219.
PATRICi32115553. VBIEscCol129921_0221.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70214 Genomic DNA. Translation: AAB08641.1.
U00096 Genomic DNA. Translation: AAC73323.1.
AP009048 Genomic DNA. Translation: BAA77889.2.
PIRiD64746.
RefSeqiNP_414754.1. NC_000913.3.
WP_001118036.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ47679.
SMRiQ47679.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261824. 6 interactors.
DIPiDIP-11225N.
STRINGi511145.b0219.

Proteomic databases

PaxDbiQ47679.
PRIDEiQ47679.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73323; AAC73323; b0219.
BAA77889; BAA77889; BAA77889.
GeneIDi946585.
KEGGiecj:JW5019.
eco:b0219.
PATRICi32115553. VBIEscCol129921_0221.

Organism-specific databases

EchoBASEiEB3118.
EcoGeneiEG13334. yafV.

Phylogenomic databases

eggNOGiENOG4105CZ7. Bacteria.
COG0388. LUCA.
HOGENOMiHOG000222700.
InParanoidiQ47679.
OMAiYKAGNER.
PhylomeDBiQ47679.

Enzyme and pathway databases

BioCyciEcoCyc:G6103-MONOMER.
ECOL316407:JW5019-MONOMER.

Miscellaneous databases

PROiQ47679.

Family and domain databases

Gene3Di3.60.110.10. 1 hit.
InterProiIPR003010. C-N_Hydrolase.
IPR001110. UPF0012_CS.
[Graphical view]
PfamiPF00795. CN_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56317. SSF56317. 1 hit.
PROSITEiPS50263. CN_HYDROLASE. 1 hit.
PS01227. UPF0012. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYAFV_ECOLI
AccessioniPrimary (citable) accession number: Q47679
Secondary accession number(s): Q9R2E1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.