Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptide transport periplasmic protein SapA

Gene

sapA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Peptide transport, Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:SAPA-MONOMER.
ECOL316407:JW1287-MONOMER.

Protein family/group databases

TCDBi3.A.1.5.42. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide transport periplasmic protein SapA
Gene namesi
Name:sapA
Ordered Locus Names:b1294, JW1287
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG20254. sapA.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 547526Peptide transport periplasmic protein SapAPRO_0000031801Add
BLAST

Proteomic databases

PaxDbiQ47622.
PRIDEiQ47622.

Interactioni

Protein-protein interaction databases

BioGridi4261257. 251 interactions.
DIPiDIP-10822N.
IntActiQ47622. 5 interactions.
MINTiMINT-1292044.
STRINGi511145.b1294.

Structurei

3D structure databases

ProteinModelPortaliQ47622.
SMRiQ47622. Positions 35-539.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108HIY. Bacteria.
COG4166. LUCA.
HOGENOMiHOG000164955.
InParanoidiQ47622.
KOiK19226.
OMAiFDISHRG.
PhylomeDBiQ47622.

Family and domain databases

InterProiIPR030678. Peptide/Ni-bd.
IPR023765. SBP_5_CS.
IPR000914. SBP_5_dom.
[Graphical view]
PfamiPF00496. SBP_bac_5. 1 hit.
[Graphical view]
PIRSFiPIRSF002741. MppA. 1 hit.
PROSITEiPS01040. SBP_BACTERIAL_5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q47622-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQVLSSLLV IAGLVSGQAI AAPESPPHAD IRDSGFVYCV SGQVNTFNPS
60 70 80 90 100
KASSGLIVDT LAAQFYDRLL DVDPYTYRLM PELAESWEVL DNGATYRFHL
110 120 130 140 150
RRDVPFQKTD WFTPTRKMNA DDVVFTFQRI FDRNNPWHNV NGSNFPYFDS
160 170 180 190 200
LQFADNVKSV RKLDNHTVEF RLAQPDASFL WHLATHYASV MSAEYARKLE
210 220 230 240 250
KEDRQEQLDR QPVGTGPYQL SEYRAGQFIR LQRHDDFWRG KPLMPQVVVD
260 270 280 290 300
LGSGGTGRLS KLLTGECDVL AWPAASQLSI LRDDPRLRLT LRPGMNVAYL
310 320 330 340 350
AFNTAKPPLN NPAVRHALAL AINNQRLMQS IYYGTAETAA SILPRASWAY
360 370 380 390 400
DNEAKITEYN PAKSREQLKS LGLENLTLKL WVPTRSQAWN PSPLKTAELI
410 420 430 440 450
QADMAQVGVK VVIVPVEGRF QEARLMDMSH DLTLSGWATD SNDPDSFFRP
460 470 480 490 500
LLSCAAIHSQ TNLAHWCDPK FDSVLRKALS SQQLAARIEA YDEAQSILAQ
510 520 530 540
ELPILPLASS LRLQAYRYDI KGLVLSPFGN ASFAGVYREK QDEVKKP
Length:547
Mass (Da):61,565
Last modified:November 1, 1996 - v1
Checksum:iEB552BB3B8E102BF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti34 – 352SG → RV (PubMed:9097039).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97282 Genomic DNA. Translation: CAA65937.1.
U00096 Genomic DNA. Translation: AAC74376.1.
AP009048 Genomic DNA. Translation: BAA14855.2.
PIRiA64878.
RefSeqiNP_415810.1. NC_000913.3.
WP_001250216.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74376; AAC74376; b1294.
BAA14855; BAA14855; BAA14855.
GeneIDi945873.
KEGGiecj:JW1287.
eco:b1294.
PATRICi32117858. VBIEscCol129921_1349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97282 Genomic DNA. Translation: CAA65937.1.
U00096 Genomic DNA. Translation: AAC74376.1.
AP009048 Genomic DNA. Translation: BAA14855.2.
PIRiA64878.
RefSeqiNP_415810.1. NC_000913.3.
WP_001250216.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ47622.
SMRiQ47622. Positions 35-539.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261257. 251 interactions.
DIPiDIP-10822N.
IntActiQ47622. 5 interactions.
MINTiMINT-1292044.
STRINGi511145.b1294.

Protein family/group databases

TCDBi3.A.1.5.42. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiQ47622.
PRIDEiQ47622.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74376; AAC74376; b1294.
BAA14855; BAA14855; BAA14855.
GeneIDi945873.
KEGGiecj:JW1287.
eco:b1294.
PATRICi32117858. VBIEscCol129921_1349.

Organism-specific databases

EchoBASEiEB4155.
EcoGeneiEG20254. sapA.

Phylogenomic databases

eggNOGiENOG4108HIY. Bacteria.
COG4166. LUCA.
HOGENOMiHOG000164955.
InParanoidiQ47622.
KOiK19226.
OMAiFDISHRG.
PhylomeDBiQ47622.

Enzyme and pathway databases

BioCyciEcoCyc:SAPA-MONOMER.
ECOL316407:JW1287-MONOMER.

Miscellaneous databases

PROiQ47622.

Family and domain databases

InterProiIPR030678. Peptide/Ni-bd.
IPR023765. SBP_5_CS.
IPR000914. SBP_5_dom.
[Graphical view]
PfamiPF00496. SBP_bac_5. 1 hit.
[Graphical view]
PIRSFiPIRSF002741. MppA. 1 hit.
PROSITEiPS01040. SBP_BACTERIAL_5. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSAPA_ECOLI
AccessioniPrimary (citable) accession number: Q47622
Secondary accession number(s): P77358
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.