Reviewed, UniProtKB/Swiss-Prot Q475Y4 (PHS1_RALEJ)

Names and origin

Protein names

Recommended name:
    Putative pterin-4-alpha-carbinolamine dehydratase 1
      Short name=PHS 1
    EC=4.2.1.96
Alternative name(s):
    4-alpha-hydroxy-tetrahydropterin dehydratase 1
    Pterin carbinolamine dehydratase 1
      Short name=PCD 1

Gene names

Ordered Locus Names:

Reut_A0417

Organism

Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) [Complete proteome] [HAMAP]

Taxonomic identifier

264198 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	116 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 116	116	Putative pterin-4-alpha-carbinolamine dehydratase 1 HAMAP MF_00434		PRO_0000231469

Sequences

	Sequence		Length	Mass (Da)
	Q475Y4-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 39F5F9632A781174	FASTA	116	12,714
	10 20 30 40 50 60 MSEKLESQTC TPCRGGIPPL ERAEAEALLV ETPGWTLADD AGRLERSFTF RNFAQALEFV 70 80 90 100 110 SGVGRLAEEQ GHHPEISFGW GHATVSWRTK KIKGLHRNDF VMAAKTSELA AGMTQG

References

[1]

"Complete sequence of chromosome 1 of Ralstonia eutropha JMP134." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000090 Genomic DNA. Translation: AAZ59799.1.
RefSeq	YP_294643.1.
3D structure databases
SMR	Q475Y4. Positions 17-113.
ModBase	Search...
Genome annotation databases
GeneID	3609524.
GenomeReviews	Gene locus Reut_A0417 in contig CP000090_GR.
KEGG	reu:Reut_A0417.
NMPDR	fig|264198.3.peg.929.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG705804.
OMA	ILTEWGK.
Enzyme and pathway databases
BioCyc	REUT264198:REUT_A0417-MONOMER.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHS1_RALEJ

Accession

Primary (citable) accession number: Q475Y4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	September 13, 2005
Last modified:	January 19, 2010
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)