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Protein

Taurine import ATP-binding protein TauB

Gene

tauB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system.UniRule annotation2 Publications

Catalytic activityi

ATP + H2O + taurine(Out) = ADP + phosphate + taurine(In).UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi34 – 41ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

  • cellular response to sulfur starvation Source: EcoCyc

Keywordsi

Molecular functionHydrolase
Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:TAUB-MONOMER
MetaCyc:TAUB-MONOMER

Protein family/group databases

TCDBi3.A.1.17.1 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Taurine import ATP-binding protein TauBUniRule annotation (EC:3.6.3.36UniRule annotation)
Gene namesi
Name:tauBUniRule annotation
Synonyms:ssiB, yaiQ
Ordered Locus Names:b0366, JW0358
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13299 tauB

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000930071 – 255Taurine import ATP-binding protein TauBAdd BLAST255

Proteomic databases

PaxDbiQ47538
PRIDEiQ47538

Expressioni

Inductioni

Regulated by CysB in response to sulfate starvation.1 Publication

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (TauB), two transmembrane proteins (TauC) and a solute-binding protein (TauA).UniRule annotation

Protein-protein interaction databases

BioGridi42610908 interactors.
IntActiQ47538 4 interactors.
STRINGi316385.ECDH10B_0322

Structurei

3D structure databases

ProteinModelPortaliQ47538
SMRiQ47538
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 229ABC transporterUniRule annotationAdd BLAST228

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. [View classification]UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IY8 Bacteria
COG4525 LUCA
InParanoidiQ47538
KOiK10831
OMAiMGRFPHV
PhylomeDBiQ47538

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR015859 ABC_transpr_TauD
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS51250 TAUB, 1 hit

Sequencei

Sequence statusi: Complete.

Q47538-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQISHLYAD YGGKPALEDI NLTLESGELL VVLGPSGCGK TTLLNLIAGF
60 70 80 90 100
VPYQHGSIQL AGKRIEGPGA ERGVVFQNEG LLPWRNVQDN VAFGLQLAGI
110 120 130 140 150
EKMQRLEIAH QMLKKVGLEG AEKRYIWQLS GGQRQRVGIA RALAANPQLL
160 170 180 190 200
LLDEPFGALD AFTRDQMQTL LLKLWQETGK QVLLITHDIE EAVFMATELV
210 220 230 240 250
LLSSGPGRVL ERLPLNFARR FVAGESSRSI KSDPQFIAMR EYVLSRVFEQ

REAFS
Length:255
Mass (Da):28,297
Last modified:November 1, 1996 - v1
Checksum:i12DDC6081CB7EA1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85613 Genomic DNA Translation: BAA12839.1
U73857 Genomic DNA Translation: AAB18089.1
U00096 Genomic DNA Translation: AAC73469.1
AP009048 Genomic DNA Translation: BAE76147.1
PIRiS78605 F64764
RefSeqiNP_414900.1, NC_000913.3
WP_000939375.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73469; AAC73469; b0366
BAE76147; BAE76147; BAE76147
GeneIDi945027
KEGGiecj:JW0358
eco:b0366
PATRICifig|1411691.4.peg.1913

Similar proteinsi

Entry informationi

Entry nameiTAUB_ECOLI
AccessioniPrimary (citable) accession number: Q47538
Secondary accession number(s): Q2MC59
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome