Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Taurine import ATP-binding protein TauB

Gene

tauB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system.UniRule annotation2 Publications

Catalytic activityi

ATP + H2O + taurine(Out) = ADP + phosphate + taurine(In).UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi34 – 41ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

  • cellular response to sulfur starvation Source: EcoCyc
  • taurine transport Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:TAUB-MONOMER.
ECOL316407:JW0358-MONOMER.
MetaCyc:TAUB-MONOMER.

Protein family/group databases

TCDBi3.A.1.17.1. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Taurine import ATP-binding protein TauBUniRule annotation (EC:3.6.3.36UniRule annotation)
Gene namesi
Name:tauBUniRule annotation
Synonyms:ssiB, yaiQ
Ordered Locus Names:b0366, JW0358
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13299. tauB.

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000930071 – 255Taurine import ATP-binding protein TauBAdd BLAST255

Proteomic databases

PaxDbiQ47538.
PRIDEiQ47538.

Expressioni

Inductioni

Regulated by CysB in response to sulfate starvation.1 Publication

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (TauB), two transmembrane proteins (TauC) and a solute-binding protein (TauA).UniRule annotation

Protein-protein interaction databases

BioGridi4261090. 8 interactors.
IntActiQ47538. 4 interactors.
STRINGi511145.b0366.

Structurei

3D structure databases

ProteinModelPortaliQ47538.
SMRiQ47538.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 229ABC transporterUniRule annotationAdd BLAST228

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. [View classification]UniRule annotation
Contains 1 ABC transporter domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IY8. Bacteria.
COG4525. LUCA.
InParanoidiQ47538.
KOiK10831.
OMAiNISKVFR.
PhylomeDBiQ47538.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015859. ABC_transpr_TauD.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51250. TAUB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q47538-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQISHLYAD YGGKPALEDI NLTLESGELL VVLGPSGCGK TTLLNLIAGF
60 70 80 90 100
VPYQHGSIQL AGKRIEGPGA ERGVVFQNEG LLPWRNVQDN VAFGLQLAGI
110 120 130 140 150
EKMQRLEIAH QMLKKVGLEG AEKRYIWQLS GGQRQRVGIA RALAANPQLL
160 170 180 190 200
LLDEPFGALD AFTRDQMQTL LLKLWQETGK QVLLITHDIE EAVFMATELV
210 220 230 240 250
LLSSGPGRVL ERLPLNFARR FVAGESSRSI KSDPQFIAMR EYVLSRVFEQ

REAFS
Length:255
Mass (Da):28,297
Last modified:November 1, 1996 - v1
Checksum:i12DDC6081CB7EA1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85613 Genomic DNA. Translation: BAA12839.1.
U73857 Genomic DNA. Translation: AAB18089.1.
U00096 Genomic DNA. Translation: AAC73469.1.
AP009048 Genomic DNA. Translation: BAE76147.1.
PIRiS78605. F64764.
RefSeqiNP_414900.1. NC_000913.3.
WP_000939375.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73469; AAC73469; b0366.
BAE76147; BAE76147; BAE76147.
GeneIDi945027.
KEGGiecj:JW0358.
eco:b0366.
PATRICi32115871. VBIEscCol129921_0377.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85613 Genomic DNA. Translation: BAA12839.1.
U73857 Genomic DNA. Translation: AAB18089.1.
U00096 Genomic DNA. Translation: AAC73469.1.
AP009048 Genomic DNA. Translation: BAE76147.1.
PIRiS78605. F64764.
RefSeqiNP_414900.1. NC_000913.3.
WP_000939375.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ47538.
SMRiQ47538.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261090. 8 interactors.
IntActiQ47538. 4 interactors.
STRINGi511145.b0366.

Protein family/group databases

TCDBi3.A.1.17.1. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiQ47538.
PRIDEiQ47538.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73469; AAC73469; b0366.
BAE76147; BAE76147; BAE76147.
GeneIDi945027.
KEGGiecj:JW0358.
eco:b0366.
PATRICi32115871. VBIEscCol129921_0377.

Organism-specific databases

EchoBASEiEB3084.
EcoGeneiEG13299. tauB.

Phylogenomic databases

eggNOGiENOG4108IY8. Bacteria.
COG4525. LUCA.
InParanoidiQ47538.
KOiK10831.
OMAiNISKVFR.
PhylomeDBiQ47538.

Enzyme and pathway databases

BioCyciEcoCyc:TAUB-MONOMER.
ECOL316407:JW0358-MONOMER.
MetaCyc:TAUB-MONOMER.

Miscellaneous databases

PROiQ47538.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015859. ABC_transpr_TauD.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51250. TAUB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTAUB_ECOLI
AccessioniPrimary (citable) accession number: Q47538
Secondary accession number(s): Q2MC59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.