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Protein

Taurine-binding periplasmic protein

Gene

tauA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of a binding-protein-dependent transport system for taurine.

GO - Biological processi

  • cellular response to sulfate starvation Source: EcoCyc
  • taurine transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:TAUA-MONOMER.
ECOL316407:JW0357-MONOMER.
MetaCyc:TAUA-MONOMER.
RETL1328306-WGS:GSTH-6616-MONOMER.

Protein family/group databases

TCDBi3.A.1.17.1. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Taurine-binding periplasmic protein
Alternative name(s):
Sulfate starvation-induced protein 1
Short name:
SSI1
Gene namesi
Name:tauA
Synonyms:ssiA, yaiR
Ordered Locus Names:b0365, JW0357
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13300. tauA.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Add
BLAST
Chaini23 – 320298Taurine-binding periplasmic proteinPRO_0000031865Add
BLAST

Proteomic databases

EPDiQ47537.
PaxDbiQ47537.
PRIDEiQ47537.

Expressioni

Inductioni

Repressed by sulfate or cysteine.

Interactioni

Protein-protein interaction databases

BioGridi4261088. 12 interactions.
IntActiQ47537. 1 interaction.
STRINGi511145.b0365.

Structurei

3D structure databases

ProteinModelPortaliQ47537.
SMRiQ47537. Positions 20-304.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4106FTQ. Bacteria.
COG4521. LUCA.
HOGENOMiHOG000265079.
InParanoidiQ47537.
KOiK15551.
OMAiGANVDWR.
OrthoDBiEOG6CZQHJ.
PhylomeDBiQ47537.

Family and domain databases

InterProiIPR007210. ABC_Gly_betaine_transp_sub-bd.
IPR010068. Peri-bd_TauA.
IPR001638. Solute-binding_3/MltF_N.
[Graphical view]
PfamiPF04069. OpuAC. 1 hit.
[Graphical view]
SMARTiSM00062. PBPb. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01729. taurine_ABC_bnd. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q47537-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAISSRNTLL AALAFIAFQA QAVNVTVAYQ TSAEPAKVAQ ADNTFAKESG
60 70 80 90 100
ATVDWRKFDS GASIVRALAS GDVQIGNLGS SPLAVAASQQ VPIEVFLLAS
110 120 130 140 150
KLGNSEALVV KKTISKPEDL IGKRIAVPFI STTHYSLLAA LKHWGIKPGQ
160 170 180 190 200
VEIVNLQPPA IIAAWQRGDI DGAYVWAPAV NALEKDGKVL TDSEQVGQWG
210 220 230 240 250
APTLDVWVVR KDFAEKHPEV VKAFAKSAID AQQPYIANPD VWLKQPENIS
260 270 280 290 300
KLARLSGVPE GDVPGLVKGN TYLTPQQQTA ELTGPVNKAI IDTAQFLKEQ
310 320
GKVPAVANDY SQYVTSRFVQ
Length:320
Mass (Da):34,266
Last modified:November 1, 1996 - v1
Checksum:iB07D54A1D2B5BE55
GO

Sequence cautioni

The sequence AAB18088.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti62 – 632AS → SA AA sequence (PubMed:8774726).Curated
Sequence conflicti66 – 661R → K AA sequence (PubMed:8774726).Curated
Sequence conflicti312 – 3121Q → P AA sequence (PubMed:8774726).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85613 Genomic DNA. Translation: BAA12838.1.
U73857 Genomic DNA. Translation: AAB18088.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73468.2.
AP009048 Genomic DNA. Translation: BAE76146.1.
PIRiS78604.
RefSeqiNP_414899.2. NC_000913.3.
WP_001018417.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73468; AAC73468; b0365.
BAE76146; BAE76146; BAE76146.
GeneIDi945030.
KEGGiecj:JW0357.
eco:b0365.
PATRICi32115869. VBIEscCol129921_0376.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85613 Genomic DNA. Translation: BAA12838.1.
U73857 Genomic DNA. Translation: AAB18088.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73468.2.
AP009048 Genomic DNA. Translation: BAE76146.1.
PIRiS78604.
RefSeqiNP_414899.2. NC_000913.3.
WP_001018417.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ47537.
SMRiQ47537. Positions 20-304.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261088. 12 interactions.
IntActiQ47537. 1 interaction.
STRINGi511145.b0365.

Protein family/group databases

TCDBi3.A.1.17.1. the atp-binding cassette (abc) superfamily.

Proteomic databases

EPDiQ47537.
PaxDbiQ47537.
PRIDEiQ47537.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73468; AAC73468; b0365.
BAE76146; BAE76146; BAE76146.
GeneIDi945030.
KEGGiecj:JW0357.
eco:b0365.
PATRICi32115869. VBIEscCol129921_0376.

Organism-specific databases

EchoBASEiEB3085.
EcoGeneiEG13300. tauA.

Phylogenomic databases

eggNOGiENOG4106FTQ. Bacteria.
COG4521. LUCA.
HOGENOMiHOG000265079.
InParanoidiQ47537.
KOiK15551.
OMAiGANVDWR.
OrthoDBiEOG6CZQHJ.
PhylomeDBiQ47537.

Enzyme and pathway databases

BioCyciEcoCyc:TAUA-MONOMER.
ECOL316407:JW0357-MONOMER.
MetaCyc:TAUA-MONOMER.
RETL1328306-WGS:GSTH-6616-MONOMER.

Miscellaneous databases

PROiQ47537.

Family and domain databases

InterProiIPR007210. ABC_Gly_betaine_transp_sub-bd.
IPR010068. Peri-bd_TauA.
IPR001638. Solute-binding_3/MltF_N.
[Graphical view]
PfamiPF04069. OpuAC. 1 hit.
[Graphical view]
SMARTiSM00062. PBPb. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01729. taurine_ABC_bnd. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source."
    van der Ploeg J.R., Weiss M.A., Saller E., Nashimoto H., Saito N., Kertesz M.A., Leisinger T.
    J. Bacteriol. 178:5438-5446(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Analysis of global responses by protein and peptide fingerprinting of proteins isolated by two-dimensional gel electrophoresis. Application to the sulfate-starvation response of Escherichia coli."
    Quadroni M., Staudenmann W., Kertesz M.A., James P.
    Eur. J. Biochem. 239:773-781(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PARTIAL PROTEIN SEQUENCE.
    Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.

Entry informationi

Entry nameiTAUA_ECOLI
AccessioniPrimary (citable) accession number: Q47537
Secondary accession number(s): P77630, Q2MC60
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 122 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.