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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei210 – 2101UniRule annotation
Active sitei656 – 6561UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciCPIN264198:GIW3-703-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Reut_A0699Imported
OrganismiCupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))Imported
Taxonomic identifieri264198 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000002697 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi264198.Reut_A0699.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q474V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQHAARPGR RSANREAPSQ ASGQSDANGA STRKTASKTP GIKPISKANL
60 70 80 90 100
MVVPANGALN ASPARRSATD KDVPLREDIR FLGRLLGECL REQEGDATFE
110 120 130 140 150
VVETIRQTAV RFRRENDRAA GTELDRLLKR LSRDQTNQVV RAFSYFSHLA
160 170 180 190 200
NIAEDQHHNR RRRIHALAGS PPQDGSLQHA LEKIDAAGVT GKQLRKFLDE
210 220 230 240 250
ALIVPVLTAH PTEVQRKSIL DAEREIARLL AERDLPMTAR ERDRNTAQLR
260 270 280 290 300
AKVTTLWQTR MLRDSRLTVA DEIDNALSYY RTTFLHGIPQ LMSELEEDIA
310 320 330 340 350
AIFPASRKTK GAAAEAAPLA PFMQMGSWIG GDRDGNPNVT AETLDHAATQ
360 370 380 390 400
QSRMILGWYL DEVHALGAEL SMSTLMVDAS PELLALAEAS PDHSAHRADE
410 420 430 440 450
PYRRALIGIY ARLAATSKML TGQGAPRHPV ADAEPYSSAE AFAADVQIVI
460 470 480 490 500
DSLRAHHGRA LTSTRIDALV RAIAVFGFHL ASVDMRQVSD VHEAVVAELF
510 520 530 540 550
AAAGVEKDYA ALPESRKLEL LLAELRQPRL LTLPYHEYSE QTRNELAILA
560 570 580 590 600
TARELRARYG QRVARNYIIS HTETLSDLVE VMLLQKEAGM LKGTLGSKTD
610 620 630 640 650
PARMELMVIP LFETIEDLQN AAGIMQSLLD LPGFDSVIEH HGVEQEVMLG
660 670 680 690 700
YSDSNKDGGF LTSNWELYKA ELALVQLFEQ RKVKLRLFHG RGGTVGRGGG
710 720 730 740 750
PTYQAILSQP PGTVNGQIRL TEQGEIINSK FANAEIGRRN LETVIAATLE
760 770 780 790 800
ASLLPQQNAP KELSTFEGIM QQLSDRAFGA YRNLVYETPG FKDYFFATTP
810 820 830 840 850
ITEIADLNLG SRPASRKLMD KKNRRIEDLR AIPWGFSWGQ CRLLLPGWYG
860 870 880 890 900
FGSAVKSLLD TAPDEKARKA AVATLRKMVK TWPFFSTLLS NMDMVLAKTD
910 920 930 940 950
LAVASRYAQL CDDAALRKNV FARISKEWHL TCEMLALVTG HQERLADNPL
960 970 980 990 1000
LARSIKNRFA YLDPLNHLQV ELLKRYRSGK DGDDIRVRRG IHLTINGVAA

GLRNTG
Length:1,006
Mass (Da):111,454
Last modified:September 13, 2005 - v1
Checksum:i05BBB9A799B99D20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000090 Genomic DNA. Translation: AAZ60081.1.
RefSeqiWP_011296886.1. NC_007347.1.
YP_294925.1. NC_007347.1.

Genome annotation databases

EnsemblBacteriaiAAZ60081; AAZ60081; Reut_A0699.
KEGGireu:Reut_A0699.
PATRICi20226859. VBIRalEut24049_1305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000090 Genomic DNA. Translation: AAZ60081.1.
RefSeqiWP_011296886.1. NC_007347.1.
YP_294925.1. NC_007347.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264198.Reut_A0699.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ60081; AAZ60081; Reut_A0699.
KEGGireu:Reut_A0699.
PATRICi20226859. VBIRalEut24049_1305.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciCPIN264198:GIW3-703-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Ralstonia eutropha JMP134."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JMP134 / LMG 1197Imported.

Entry informationi

Entry nameiQ474V2_CUPPJ
AccessioniPrimary (citable) accession number: Q474V2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 27, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.