ID   G6PI1_RALEJ             Reviewed;         545 AA.
AC   Q472C7;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 27.
DE   RecName: Full=Glucose-6-phosphate isomerase 1;
DE            Short=GPI 1;
DE            EC=5.3.1.9;
DE   AltName: Full=Phosphoglucose isomerase 1;
DE            Short=PGI 1;
DE   AltName: Full=Phosphohexose isomerase 1;
DE            Short=PHI 1;
GN   Name=pgi1; OrderedLocusNames=Reut_A1386;
OS   Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=264198;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M.,
RA   Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Ralstonia eutropha JMP134.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the GPI family.
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DR   EMBL; CP000090; AAZ60756.1; -; Genomic_DNA.
DR   RefSeq; YP_295600.1; -.
DR   GeneID; 3611179; -.
DR   GenomeReviews; CP000090_GR; Reut_A1386.
DR   KEGG; reu:Reut_A1386; -.
DR   NMPDR; fig|264198.3.peg.2140; -.
DR   HOGENOM; Q472C7; -.
DR   OMA; Q472C7; GPKIVSQ.
DR   BioCyc; REUT264198:REUT_A1386-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   HAMAP; MF_00473; -; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR   PANTHER; PTHR11469; G6P_Isomerase; 1.
DR   Pfam; PF00342; PGI; 1.
DR   PRINTS; PR00662; G6PISOMERASE.
DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1.
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase.
FT   CHAIN         1    545       Glucose-6-phosphate isomerase 1.
FT                                /FTId=PRO_0000230929.
FT   ACT_SITE    356    356       Proton donor (By similarity).
FT   ACT_SITE    387    387       By similarity.
FT   ACT_SITE    508    508       By similarity.
SQ   SEQUENCE   545 AA;  59755 MW;  E29376EAA5B69B83 CRC64;
     MPTNLHAWNA LQQHHDAIRD HQMADWFAEN GADRVRQFSL EAAGLYLDYS KNRITPQTMQ
     LLLQLADEAG VPARRDAMFA GEHINATEDR AALHVALRAT AGAGFKVDGV PVVPAIQNVL
     VRMRAFSEAV RSGAWTGTTG ERITDVVNIG IGGSDLGPKM VCRALSHLAH DDGHSGPRMH
     FVSNVDGTEL AEALERLDPR RTLMIVCSKT FTTLETMANA HSARQWYLDN GVAEDQLARH
     FVAVSTNVDA VRAFGIDPAN MFEFWDWIGG RFSLWSSVGL STALAVGFNA FADLLAGGRA
     MDEHFRTAPL ERNMPVVLGM LGIWYRNFFN LPTSCMAPYS TSLELFPAFL QQLEMESNGK
     TVQLNGRRVR THTSPVVWGT AGTNGQHAYF QMIHQGSQIV PVDFVAPLVP PRELPGHHAK
     LLANCFAQAE ALMRGRSAEE LRAAGMTDEL RIAHMVFEGN RPSNTLLMED LTPHVLGALI
     ALYEHRTFVQ GVVWNINSFD QWGVELGKIL ARPIESELNG AQAGSHDAST AALIARARGV
     LARNG
//