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Q472C7

- G6PI1_CUPPJ

UniProt

Q472C7 - G6PI1_CUPPJ

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Protein
Glucose-6-phosphate isomerase 1
Gene
pgi1, Reut_A1386
Organism
Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donor By similarity
Active sitei387 – 3871 By similarity
Active sitei508 – 5081 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCPIN264198:GIW3-1403-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase 1 (EC:5.3.1.9)
Short name:
GPI 1
Alternative name(s):
Phosphoglucose isomerase 1
Short name:
PGI 1
Phosphohexose isomerase 1
Short name:
PHI 1
Gene namesi
Name:pgi1
Ordered Locus Names:Reut_A1386
OrganismiCupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Taxonomic identifieri264198 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000002697: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 545545Glucose-6-phosphate isomerase 1UniRule annotation
PRO_0000230929Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264198.Reut_A1386.

Structurei

3D structure databases

ProteinModelPortaliQ472C7.
SMRiQ472C7. Positions 3-539.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q472C7-1 [UniParc]FASTAAdd to Basket

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MPTNLHAWNA LQQHHDAIRD HQMADWFAEN GADRVRQFSL EAAGLYLDYS    50
KNRITPQTMQ LLLQLADEAG VPARRDAMFA GEHINATEDR AALHVALRAT 100
AGAGFKVDGV PVVPAIQNVL VRMRAFSEAV RSGAWTGTTG ERITDVVNIG 150
IGGSDLGPKM VCRALSHLAH DDGHSGPRMH FVSNVDGTEL AEALERLDPR 200
RTLMIVCSKT FTTLETMANA HSARQWYLDN GVAEDQLARH FVAVSTNVDA 250
VRAFGIDPAN MFEFWDWIGG RFSLWSSVGL STALAVGFNA FADLLAGGRA 300
MDEHFRTAPL ERNMPVVLGM LGIWYRNFFN LPTSCMAPYS TSLELFPAFL 350
QQLEMESNGK TVQLNGRRVR THTSPVVWGT AGTNGQHAYF QMIHQGSQIV 400
PVDFVAPLVP PRELPGHHAK LLANCFAQAE ALMRGRSAEE LRAAGMTDEL 450
RIAHMVFEGN RPSNTLLMED LTPHVLGALI ALYEHRTFVQ GVVWNINSFD 500
QWGVELGKIL ARPIESELNG AQAGSHDAST AALIARARGV LARNG 545
Length:545
Mass (Da):59,755
Last modified:September 13, 2005 - v1
Checksum:iE29376EAA5B69B83
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000090 Genomic DNA. Translation: AAZ60756.1.
RefSeqiYP_295600.1. NC_007347.1.

Genome annotation databases

EnsemblBacteriaiAAZ60756; AAZ60756; Reut_A1386.
GeneIDi3611179.
KEGGireu:Reut_A1386.
PATRICi20228289. VBIRalEut24049_2007.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000090 Genomic DNA. Translation: AAZ60756.1 .
RefSeqi YP_295600.1. NC_007347.1.

3D structure databases

ProteinModelPortali Q472C7.
SMRi Q472C7. Positions 3-539.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 264198.Reut_A1386.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ60756 ; AAZ60756 ; Reut_A1386 .
GeneIDi 3611179.
KEGGi reu:Reut_A1386.
PATRICi 20228289. VBIRalEut24049_2007.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci CPIN264198:GIW3-1403-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Ralstonia eutropha JMP134."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JMP134 / LMG 1197.

Entry informationi

Entry nameiG6PI1_CUPPJ
AccessioniPrimary (citable) accession number: Q472C7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: September 13, 2005
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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