Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase 1

Gene

pgi1

Organism
Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donorUniRule annotation
Active sitei387 – 3871UniRule annotation
Active sitei508 – 5081UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCPIN264198:GIW3-1403-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase 1UniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPI 1UniRule annotation
Alternative name(s):
Phosphoglucose isomerase 1UniRule annotation
Short name:
PGI 1UniRule annotation
Phosphohexose isomerase 1UniRule annotation
Short name:
PHI 1UniRule annotation
Gene namesi
Name:pgi1UniRule annotation
Ordered Locus Names:Reut_A1386
OrganismiCupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Taxonomic identifieri264198 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000002697 Componenti: Chromosome 1

Subcellular locationi

  1. Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 545545Glucose-6-phosphate isomerase 1PRO_0000230929Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264198.Reut_A1386.

Structurei

3D structure databases

ProteinModelPortaliQ472C7.
SMRiQ472C7. Positions 3-539.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q472C7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTNLHAWNA LQQHHDAIRD HQMADWFAEN GADRVRQFSL EAAGLYLDYS
60 70 80 90 100
KNRITPQTMQ LLLQLADEAG VPARRDAMFA GEHINATEDR AALHVALRAT
110 120 130 140 150
AGAGFKVDGV PVVPAIQNVL VRMRAFSEAV RSGAWTGTTG ERITDVVNIG
160 170 180 190 200
IGGSDLGPKM VCRALSHLAH DDGHSGPRMH FVSNVDGTEL AEALERLDPR
210 220 230 240 250
RTLMIVCSKT FTTLETMANA HSARQWYLDN GVAEDQLARH FVAVSTNVDA
260 270 280 290 300
VRAFGIDPAN MFEFWDWIGG RFSLWSSVGL STALAVGFNA FADLLAGGRA
310 320 330 340 350
MDEHFRTAPL ERNMPVVLGM LGIWYRNFFN LPTSCMAPYS TSLELFPAFL
360 370 380 390 400
QQLEMESNGK TVQLNGRRVR THTSPVVWGT AGTNGQHAYF QMIHQGSQIV
410 420 430 440 450
PVDFVAPLVP PRELPGHHAK LLANCFAQAE ALMRGRSAEE LRAAGMTDEL
460 470 480 490 500
RIAHMVFEGN RPSNTLLMED LTPHVLGALI ALYEHRTFVQ GVVWNINSFD
510 520 530 540
QWGVELGKIL ARPIESELNG AQAGSHDAST AALIARARGV LARNG
Length:545
Mass (Da):59,755
Last modified:September 13, 2005 - v1
Checksum:iE29376EAA5B69B83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000090 Genomic DNA. Translation: AAZ60756.1.
RefSeqiWP_011297555.1. NC_007347.1.
YP_295600.1. NC_007347.1.

Genome annotation databases

EnsemblBacteriaiAAZ60756; AAZ60756; Reut_A1386.
KEGGireu:Reut_A1386.
PATRICi20228289. VBIRalEut24049_2007.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000090 Genomic DNA. Translation: AAZ60756.1.
RefSeqiWP_011297555.1. NC_007347.1.
YP_295600.1. NC_007347.1.

3D structure databases

ProteinModelPortaliQ472C7.
SMRiQ472C7. Positions 3-539.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264198.Reut_A1386.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ60756; AAZ60756; Reut_A1386.
KEGGireu:Reut_A1386.
PATRICi20228289. VBIRalEut24049_2007.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciCPIN264198:GIW3-1403-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Ralstonia eutropha JMP134."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JMP134 / LMG 1197.

Entry informationi

Entry nameiG6PI1_CUPPJ
AccessioniPrimary (citable) accession number: Q472C7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: September 13, 2005
Last modified: April 29, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.